Cell culture
GFL 1002 Water Bath
Jouan CR3i Centrifuge
ThermoScientificHeracell 150i Incubator
WTB Binder 37 0C CO2 Free Incubator
HeidolphTitramax 1000 Shaker
Olympus CH40 Microscope
OlympusInverted Microscope
ThermoHerasafeLaminar Flow Cabinet
CliftonCycloneVortex
Flow Cytometry
BD FACS Aria-2 Flow Cytometer
Beckman CoulterCytoflex Flow Cytometry Device
RibbyStuartMixerVortex
BoschCooler +4 0C Refrigerator
BD Probetec Sonicator
Microarray System
Affymetrix Gene ChipScanner
Affymetrix Gene ChipFluidics Station 450
Affymetrix Gene ChipHybridizationOven 645
Cooling Systems
+4 0C Cold Room
ThermoElectron Corporation Herafreeze -80 0C Freezer
Bosch -20 0C Freezer
Bosch No Frost System+4 0C Refrigerator
Thermolyne Locator-8 Liquid Nitrogen Tank
MVE Cryosystem 4000 Liquid Nitrogen Tank
Microscopes
Olympus BX51 Fluorescent Microscope
Olympus BX50 Microscope
Shakers
Biosan Mini RockerRotator Shaker
IKA KS 260 Basic Shaker
Biosan MR-1 Mini Rocker Shaker
Scales
Denver Instruments Precision Balance
Shimadzu AW20 Precision Balance
Centrifuges
Eppendorf Mini Spin Centrifuge
Eppendorf 5417R Centrifuge
HerausBiofugeFresco Centrifuge
Hettich EBA-III Centrifuge
Jouan MR22i Centrifuge
ThermoMegafuge 40R Centrifuge
Water Baths
GFL Heater Water Bath
Grant OLS 200 Water Bath
MemmertShaker Water Bath
Kotterman Water Bath
PCR Sistemleri
CorbettResearchRotorgene 6000 Real-Time 5 PlexThermalCycler
ThermoScientific Arktik ThermalCycler
Biorad CFX Connect Real-Time System
NanoDrop ND-1000 Spektrofotometre
Yatay Elektroforez Tankları
LKB Bromma 2301 Macrodrive-1 Güç Kaynağı
Wealtec Elite 300 Plus Güç Kaynağı
Imperial Mikrodalga Fırın
Western Blotting Sistemleri
Biorad Mini ProteanTetra Cell Western Blotting Sistemi
ThermoScientificOwlTM Dual Gel Western Blotting Sistemi
ThermoScientific Pierce FastSemidryBlotlama Cihazı
InvitrogeniBlotBlotlama Cihazı
ThermoScientific EC 300 XL Güç Kaynağı
AmershamBiosciencesElectrophoresis Güç Kaynağı
IKA RH Basic-2 Hotplate Manyetik Karıştırıcı
WTW Series InoLab 720 pH Metre
Techne DB-2D Kuru Blok Isıtıcı
Kodak Gel Logic 1500 Jel Görüntüleme Sistemi
ELISA System
MultiWash Plus Micro-Plate Washer
MolecularDevicesSpectramax Plus Spectrophotometer
Experimental Animals Infrastructure
TechniplastHepa Isolator Animal Cabinet with Filtration System
Ehret Isolator Animal Cabinet
Desis THB Precision Balance
DanLaf VFB 1206 Laminar Flow Cabinet
Arçelik -20 0C Deep Freezer
IsoLabVortex
Homogenizers
BioblockScientificPolytron Tissue Homogenizer
Mini BeadBeater Homogenizer
İncubators
HerausIncubator
WTB Binder VD-53 37 0C CO2 Free Vacuum Incubator
Other
Jouan Vacuum Concentrator System
ScientificIndustries Inc. MultipurposeRotator
ThermoBriteStatspinHybridization Bath
WTB Binder Dry Air Sterilizer
MilliporeRIOs-DI 3UV Distilled Water Device
Faculty Members
Prof. Dr. A.Lale Doğan
Prof.Dr. Güneş Esendağlı
Doç.Dr. Füsun Özmen
Doç.Dr. Hande Canpınar
Doç.Dr. Gürcan Günaydın
Dr. Öğr. Üyesi Begüm Kocatürk
Graduate Students
Ahmet Erim Pamuk
Göksu Sarıoğlu
Zühre Kaya
Başak Dalkıran
Gözde Bilir
Ceren Narin
Anıl Işık
İlknur Gündüz
Hatice Toprak Doğramacı
Gaye Pişiren
Nazire Pınar Acar Özen
PhD Students
Emre Gedik
Rüveyda Ayasun
Sarp Uzun
Ece Tavukçuoğlu
Burcu Karadal
Senanur Arbağ
Sefa Özdemir
Turçin Sarıdoğan
Başak Sayınalp
Selda Karaaslan
Merve Özcan
Elif Çakan
Mubaida Parveen
Hamdullah Yanık
Cemre Kalaycı
Şafak Ceren Uslu
Çiğdem Elif Çelik
Feyza Özbay
Melek Günindi Korkut
Ayşe Ece Gülen
Ranya Erdal
Muhammed Doğukan Aksu
Sakine Ulusoy
1. The Role of Eukaryotic Elongation Factor2 Kinase eEF2K Activation in Breast Cancer Cells with HER2 Expression ( BAB Project, coordinator Prof. Dr. A.Lale Doğan)
2. Investigation of the Radiosensitizer Role of Metformin Added to Simultaneous Radiotherapy with Cisplatin in Cervical Squamous Cell Cancer Cell Lines (BAB Project, assistant researcher Assoc.Dr. Gürcan Günaydın)
3. Investigation of the Effect of AMPK Modulation on Cell Proliferation in Uveal Melanoma Cell Lines (BAB Project, co-researcher Assoc. Dr. Gürcan Günaydın)
4. Evaluation of serum leptin, adiponectin, resistin, TNF-a, IL-1, IL-6, IL-7, IL-10 levels in patients with newly diagnosed metastatic colorectal cancer using biological agents in the treatment (BAB Project, co-researcher Assoc. Gurcan Good Morning)
5. Investigation of Biomarkers related to Angiogenesis in Laryngeal Cancer (BAB Project, associate researcher Assoc. Dr. Gürcan Günaydın)
6. Expression and Regulation of APOBEC / AID Family Members in Diffuse Large B-Cell Lymphomas (DLBCL) (BAB Project, associate researcher Associate Professor Gürcan Günaydın)
7. Evaluation of estrogen, progesterone and androgen receptors and aromatase enzyme expression in fresh tissue and paraffin block samples of normal adrenal gland and adrenocortical carcinoma by real time PCR and western blot and obtaining cell culture from fresh cancerous tissues (BAB Project, assistant researcher Assoc. Gurcan Good Morning)
8. Comparison of Endothelial OXLDL Receptor Amounts in Internal Mammarian Artery Artery and Saphenous Vein Grafts Used in Coronary Bypass Surgery (BAB Project, co-researcher Assoc. Dr. Hande Canpınar)
9. Investigation of oxidative stress caused by cariogenic bacteria in dental pulp cell (BAB Project, assistant researcher Assoc. Dr. Hande Canpınar)
10. Evaluation of Possible Apoptotic Antioxidant and Genotoxic Effects of Pitavastatin in Human Cervical Cancer Cell Line BAB Project, assistant researcher Assoc. Hande Canpinar)
11. Investigation of the Phenotypic and Functional Effects of Idarubicin and Cytarabine Agents Used in the Treatment of AML on NK Cells (BAB Project, coordinator Associate Prof. Dr. Füsun Özmen)
12. The Relationship Between MUC1 MUC4 MUC16 Molecules and Treg Cells and Epithelial Mesenchymal Transition (EMT) in Pancreatic Cancer (BAB Project, Executive Associate Professor Dr. Füsun Özmen)
13. “Examination of T Cell Activation and Memory Responses within the Scope of a Randomized, Double-Blind, Placebo-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of Inactivated SARS-CoV-2 Vaccine (Vero Cell)”, TÜSEBSStrategic Research and DevelopmentProjects Support no.Program,Project 9401(coordinator), December 2020 – Prof. Dr. Gunes Esendagli
14. “Synthesis and Characterization of New Hexahydroquinoline Derivatives, Investigation of Inhibitory Effects and Anticancer Activities on the Transforming Growth Factor Beta TGF, In Silico Detection of Interactions with Molecular Targets”, TSA-2020-18838 Hacettepe University Scientific Research Projects Coordination Unit –Comprehensive Research Project, October 2020– Prof. Dr. Gunes Esendagli
15. “Molecular - functional analysis and evaluation of neutrophil subpopulations in colorectal cancer as biomarkers”, TSA-2020-18770, Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Research Project (coordinator), August 2020– Prof. Dr. Gunes Esendagli
16. “Development of Nanocarrier System Containing Immunotherapeutic Targeted to the Tumor Microenvironment for the Treatment of Non-Small Cell Lung Cancer and Evaluation in Vitro/In Vivo” 119R055TÜBİTAK-1001 – Health Sciences Research Group (consultant), December 2019– Prof. Dr. Gunes Esendagli
17. “Investigation of the Effect of Microtubule Inhibitors on the Levels of Hazard-related Molecular Patterns in Cancer Cells”TYL-2020-18737, Hacettepe University Scientific Research Projects Coordination Unit – Master Thesis Project (director), June 2020– Prof.Dr. Dr. Gunes Esendagli
18. “The Effect of Surgical Field Fluids on Neutrophil Differentiation and Functions” TDK-2019-18328 Hacettepe University Scientific Research Projects Coordination Unit – PhD Project (coordinator), November 2019– Prof.Dr. Dr. Gunes Esendagli
19. “Testing treatment resistance in breast cancer in three-dimensional spheroid cell co-cultures and developing an inferential mathematical model” TÇP-2019-18245Hacettepe University Scientific Research Projects Coordination Unit – Invited Project (assistant researcher), October 2019– Prof. Dr. Gunes Esendagli
20. “Development and In Vitro/In Vivo Evaluation of Orally Applied Nanoparticular Drug Delivery System for Local Treatment of Colorectal Cancers” Project no.8956 Erciyes University Scientific Research Projects Coordination Unit – Priority Area Research Project (assistant researcher), October 2018 – Prof. Dr. Gunes Esendagli
21. “Investigation of Genetic and Immunological Determinants of Treatment Response in Cancer Patients Planned to Receive Immune Checkpoint Blockage Therapy” TSA-2019-18199 Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Project (assistant researcher), December 2019 – Prof. Dr. Gunes Esendagli
22. “Evaluation of the Protective Effect of Chlorocogic Acid Derived Mannich Base Compound against UV-Induced Melanoma” THD-2019-18035 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (assistant researcher), May 2019 – Prof. Dr. Gunes Esendagli
23. “Synthesis of Protein-Caged Nanoparticles with Synergistic Anti-Cancer Effect of Photothermal and Endoperoxide Therapies and In-Vivo Investigation of Effects against Melanoma Skin Cancer” 217Z027 TÜBİTAK – Basic Sciences Research Group (consultant), May 2018– Prof. Dr. Gunes Esendagli
24. “Active Targeting of Irinotecan and STAT3 Inhibitor Loaded PLGA-PEG Nanoparticles to Small Cell Lung Cancer and In Vivo-In Vitro Evaluation” 217S449 TÜBİTAK-1001 – Health Sciences Research Group (consultant), October 2018 – Prof. Dr. Gunes Esendagli
25. “In Vitro- In Vivo Evaluation of the Efficacy and Safety of Immunochemotherapeutic Nanoplexes in the Treatment of Colon Cancer” 217S610 TÜBİTAK-1001 – Health Sciences Research Group (assistant researcher), October 2018 - Prof. Dr. Gunes Esendagli
26. “Nano-Immunotherapy: Intracellular Targeting of Cancer Cells and Tumor-Associated Macrophages (2-INTRATARGET)” 217S068 European Research Area (ERANET) project (associate researcher), April 2018 – Prof. Dr. Gunes Esendagli
27. “Examination of thymopoiesis and germinal center cellular components in Myasthenia Gravis-related thymectomy materials and peripheral blood” TSA-2017-15499 Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Project (assistant researcher), December 2017 - Prof. Dr. Gunes Esendagli
28. “Investigation of the antitumoral activity of paclitaxel-loaded cyclodextrin nanoparticles” TSA-2017-14496 Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Project (assistant researcher), August 2017 - Prof. Dr. Gunes Esendagli
29. “Investigation of the effect of leptin on spermatogonial stem cell cryopreservation” THD-2017-13430 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (assistant researcher), June 2017 – June 2018. Prof.Dr. Dr. Gunes Esendagli
30. “Comparative Analysis of Spleen and Peripheral Blood Myeloid-Derived Suppressor Cells in Gastric and Pancreatic Cancer” 216S264 TÜBİTAK-1002 – Health Sciences Research Group (coordinator), September 2017 – September 2018. Prof.Dr. Dr. Gunes Esendagli
31. “Rational Design and Development of Radionuclide-Labeled Molecules Targeting the Tumor Micro-Environment with High Selectivity for Use in Pet Imaging Systems” 116E644TÜBİTAK-1003 – Electrical, Electronics and Informatics Research Group(director), March 2018 – Prof. Dr. Gunes Esendagli
32. “Preparation of Bevacizumab Loaded Nanoparticulate Drug Delivery Systems Targeted to the Brain and In Vitro-In Vivo Evaluation of Their Efficiency” 216S704TÜBİTAK-1003 – Health Sciences Research Group (assistant researcher), March 2018 – Prof. Dr. Gunes Esendagli
33. “In vivo Effects of Usnic Acid Secondary Metabolite on Mammary Carcinoma Formed by 4T1 Cells in Mice” THD-2017-10712 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (assistant researcher), February 2017 – November 2017 Prof.Dr. Dr. Gunes Esendagli
34. “Effect of acute myeloid leukemia cells expressing PDL2 costimulator molecule on helper T cell activation” TSA-2017-12739 Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Project (manager), January 2017 – May 2018 Prof.Dr. Dr. Gunes Esendagli
35. “Formulation and Determination of the Efficacy of Active Targeted Nanoscale Theranostic Combined Drug Delivery Systems for Non-Small Cell Lung Cancer” TSA-2017-12852 Hacettepe University Scientific Research Projects Coordination Unit – Comprehensive Project (assistant researcher), February 2017 – Prof. Dr. Gunes Esendagli
36. “Nanopharmaceuticals Design and In vitro Evaluation of Nano-Scale Drug Delivery Systems for Active Targeting in Breast Cancer Treatment” THD-2017-11642 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (assistant researcher), January 2017 – May 2018 Prof.Dr. Dr. Gunes Esendagli
37. “Immunological effects of liver resection in liver metastasis of breast cancer” THD-2017-12708 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (assistant researcher), February 2017 – February 2018 Prof. Dr. Gunes Esendagli
38. “Investigation of B7 family costimulatory molecules in B lymphoma cells and their effects on T cell activation and fatigue” THD-2016-12954 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (director), December 2016 – December 2017 Prof.Dr. Dr. Gunes Esendagli
39. “Investigation of B7 family costimulatory molecules in small cell lung cancer cells and their effects on T cell activation and fatigue” 315S034 TÜBİTAK-3001 – Health Sciences Research Group (consultant), April 2016 – November 2017 Prof.Dr. Dr. Gunes Esendagli
40. “Evaluation of Transcript Variants of Myeloid-Originated Suppressor Cell Surface Molecules as Specific and Novel Biomarkers” 115S636 TÜBİTAK – Health Sciences Research Group and European Cooperation in Science and Technology (COST) Project, BM1404 “European Investigators of European Investigators- Celloidal Exploratory” coordinator), September 2015 – September 2018. Prof. Dr. Gunes Esendagli
41. “Effects of aspirin on tumor immunology in splenectomized mice” Bezmialem Vakıf University Scientific Research Unit – Support Project (assistant researcher), April 2016- April 2017 Prof. Dr. Gunes Esendagli
42. “Effect of inducible costimulatory ligand (ICOS-LG) expressing on T lymphocytactivation and fatigue of acute myeloid leukemia (AML) cells” THD-2015-6720 Hacettepe University Scientific Research Projects Coordination Unit – Support Project (director), June 2015 – April 2016 Prof.Dr. Dr. Gunes Esendagli
1. Bruger AM, Dorhoi A, Esendagli G, Barczyk-Kahlert K, van der Bruggen P,Lipoldova M, Perecko T, Santibanez J, Saraiva M, Van Ginderachter JA, Brandau S.How to measure the immunosuppressive activity of MDSC: assays, problems andpotential solutions. Cancer Immunol Immunother. 2019 Apr;68(4):631-644. doi:10.1007/s00262-018-2170-8. Epub 2018 May 21. PMID: 29785656.
2. Kursunel MA, Esendagli G. The untold story of IFN-γ in cancer biology.Cytokine Growth Factor Rev. 2016 Oct;31:73-81. doi:10.1016/j.cytogfr.2016.07.005. Epub 2016 Aug 1. Erratum in: Cytokine GrowthFactor Rev. 2017 Jun;35:97. PMID: 27502919.
3. Yoyen-Ermis D, Tunali G, Tavukcuoglu E, Horzum U, Ozkazanc D, Sutlu T,Buyukasik Y, Esendagli G. Myeloid maturation potentiates STAT3-mediated atypicalIFN-γ signaling and upregulation of PD-1 ligands in AML and MDS. Sci Rep. 2019Aug 12;9(1):11697. doi: 10.1038/s41598-019-48256-4. PMID: 31406210; PMCID:
4. Winklmeier S, Schlüter M, Spadaro M, Thaler FS, Vural A, Gerhards R, MacriniC, Mader S, Kurne A, Inan B, Karabudak R, Özbay FG, Esendagli G, Hohlfeld R,Kümpfel T, Meinl E. Identification of circulating MOG-specific B cells inpatients with MOG antibodies. Neurol Neuroimmunol Neuroinflamm. 2019 Oct14;6(6):625. doi: 10.1212/NXI.0000000000000625. Erratum in: Neurol NeuroimmunolNeuroinflamm. 2019 Nov 15;7(1): PMID: 31611268; PMCID: PMC6857907.
5. Bruger AM, Vanhaver C, Bruderek K, Amodio G, Tavukçuoğlu E, Esendagli G,Gregori S, Brandau S, van der Bruggen P. Protocol to assess the suppression ofT-cell proliferation by human MDSC. Methods Enzymol. 2020;632:155-192. doi:10.1016/bs.mie.2019.05.046. Epub 2019 Jul 8. PMID: 32000895.
6. Yoyen-Ermis D, Ozturk-Atar K, Kursunel MA, Aydin C, Ozkazanc D, Gurbuz MU,Uner A, Tulu M, Calis S, Esendagli G. Tumor-Induced Myeloid Cells Are Reduced byGemcitabine-Loaded PAMAM Dendrimers Decorated with Anti-Flt1 Antibody. MolPharm. 2018 Apr 2;15(4):1526-1533. doi: 10.1021/acs.molpharmaceut.7b01075. Epub2018 Mar 6. PMID: 29481086.
7. Tokgöz MA, Atik OŞ, Esendağlı G, Öğüt B, Bozkurt HH. Is it possible that the pathogenesis of osteoarthritis could start with subchondral trabecular bone loss like osteoporosis? Eklem Hastalik Cerrahisi. 2018 Dec;29(3):152-8. doi:10.5606/ehc.2018.007. PMID: 30376799.
8. Cassetta L, Bruderek K, Skrzeczynska-Moncznik J, Osiecka O, Hu X, Rundgren IM, Lin A, Santegoets K, Horzum U, Godinho-Santos A, Zelinskyy G, Garcia-TellezT, Bjelica S, Taciak B, Kittang AO, Höing B, Lang S, Dixon M, Müller V, UtikalJS, Karakoç D, Yilmaz KB, Górka E, Bodnar L, Anastasiou OE, Bourgeois C, BaduraR, Kapinska-Mrowiecka M, Gotic M, Ter Laan M, Kers-Rebel E, Król M, SantibañezJF, Müller-Trutwin M, Dittmer U, de Sousa AE, Esendağlı G, Adema G, Loré K,Ersvær E, Umansky V, Pollard JW, Cichy J, Brandau S. Differential expansion ofcirculating human MDSC subsets in patients with cancer, infection andinflammation. J Immunother Cancer. 2020 Sep;8(2):e001223. doi:10.1136/jitc-2020-001223. PMID: 32907925; PMCID: PMC7481096.
9. Yoyen-Ermis D, Tunali G, Tavukcuoglu E, Horzum U, Ozkazanc D, Sutlu T,Buyukasik Y, Esendagli G. Myeloid maturation potentiates STAT3-mediated atypicalIFN-γ signaling and upregulation of PD-1 ligands in AML and MDS. Sci Rep. 2019Aug 12;9(1):11697. doi: 10.1038/s41598-019-48256-4. PMID: 31406210; PMCID:PMC6691003.
10. Winklmeier S, Schlüter M, Spadaro M, Thaler FS, Vural A, Gerhards R, MacriniC, Mader S, Kurne A, Inan B, Karabudak R, Özbay FG, Esendagli G, Hohlfeld R,Kümpfel T, Meinl E. Identification of circulating MOG-specific B cells inpatients with MOG antibodies. Neurol Neuroimmunol Neuroinflamm. 2019 Oct14;6(6):625. doi: 10.1212/NXI.0000000000000625. Erratum in: Neurol NeuroimmunolNeuroinflamm. 2019 Nov 15;7(1): PMID: 31611268; PMCID: PMC6857907.
11. Bruger AM, Vanhaver C, Bruderek K, Amodio G, Tavukçuoğlu E, Esendagli G,Gregori S, Brandau S, van der Bruggen P. Protocol to assess the suppression ofT-cell proliferation by human MDSC. Methods Enzymol. 2020;632:155-192. doi:10.1016/bs.mie.2019.05.046. Epub 2019 Jul 8. PMID: 32000895.
12. Gurses KM, Yalcin MU, Kocyigit D, Canpinar H, Evranos B, Yorgun H, Sahiner ML, Kaya EB, Ozer N, Tokgozoglu L, Oto MA, Guc D, Aytemir K. . Effects of Persistent Atrial Fibrillation on Serum 15. Galectin-3 Levels. Am J Cardiol. Am J Cardiol. 2015 Mar 1;115(5):647-51
13. Yalcin MU, Gurses KM, Kocyigit D, Canpinar H, Canpolat U, Evranos B, Yorgun H, Sahiner ML, Kaya EB, Hazirolan T, Tokgozoglu L, Oto MA, Ozer N, Guc D, Aytemir K. The Association of Serum Galectin-3 Levels with Atrial Electrical and Structural Remodeling.J Cardiovasc Electrophysiol. 2015 Feb 14.
14 . Gurses KM, Kocyigit D, Yalcin MU, Canpinar H, Oto MA, Ozer N, Tokgozoglu L, Guc D, Aytemir K. Enhanced Platelet Toll-like Receptor 2 and 4 Expression in Acute Coronary Syndrome and Stable Angina Pectoris. Am J Cardiol. 2015 Dec 1;116(11):1666-71
15. Gurses KM, Kocyigit D, Yalcin UM , Canpinar H, Yorgun H, Sahiner ML , Baris E, Oto MA, Ozer N, Guc D, Aytemir K.Monocyte Toll- Like Receptor Expression in Patients with Atrial Fibrillation. Am J Cardiol. Am J Cardiol. 2016. DOI:10.1016/j.amjcard.2016.02.014
16.. Halacli B, Unver N, Oskay Halacli S, Canpinar H, Ortac Ersoy E, Ocal S, Guc D, Buyukasik, Y, Topeli A. Investigation of Hemophagocytic Lymphohistiocytosis in Severe Sepsis Patients. Journal of Critical Care 2016, doi: 10.1016/j.jcrc.2016.04.034
17. Kılıç Süloğlu A, SelmanoğluG, , Yılmaz Ş, Canpınar H. Comparison of Phototoxic Effects of Hypericin Mediated Photodynamic Therapy 1 in HT-29 and Caco-2 Colon Cancer Cells. Turkish Journal Of Biology 40: 1202-1218 2016 DOI: 10.3906/biy-1510-43
18.. Kocyigit D, Gurses KM,Yalcin UM, Canpinar H, Canpolat U,Evranos B, Yorgun H, ozer N, Guc D, Aytemir K. Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation Journal of Clinical Laboratory Analysis, March 2017,DOI: 10.1002/jcla.22120
19. Gurses KM. ,Kocyigit D, Yalcin MU, Canpinar H, Evranos B, Canpolat U,Yorgun, H Sahiner L, Guc D, Aytemir K.Platelet Toll-like receptor and its ligand HMGB-1 expression is increased inthe left atrium of atrial fibrillation patients. Cytokine 103 (2018) 50–56
20. Güçlü D , Kuzu B, Tozlu İ, Taşpınar F, Canpınar H, Taşpınar M, Menges N. Synthesis of Novel Imidazopyridines and Their Biological Evaluation as PotentAnticancer Agents: A Promising Candidate for Glioblastoma Bioorganic & Medicinal Chemistry Letters, 2018 15;28(15):2647-2651
21. Greco D, Kocyigit D, Adorni M.P , Marchi C , Ronda N, Bernini F, Gurses KM , Canpinar H, Guc D, Oguz SH, Gurlek , Strazzella A,Simonelli S, Tokgozoglu L, F. Zimetti F. Vitamin D replacement ameliorates serum lipoprotein functions, adipokine profile and subclinical atherosclerosis in pre-menopausal women. Nutrition, Metabolism & Cardiovascular Diseases (2018) 28, 822-829
22.Ozcan M , Esendagli G, Musdal , Canpinar H,Bacanlı M, Anlar HG, Esendağlı‐Yılmaz G, Beyramzadeh M,Aksoy Y.Dualactions of the antioxidant chlorophyllin, a glutathione transferase P1‐1 i nhibitor, in tumorigenesis and tumor progression. J Cell Biochem. 2018;1-11.
23. Gürses KM, Yalçın MU, Koçyiğit D, Beşler MS, Canpınar H, Evranos B, Yorgun H, Şahiner ML, Kaya EB, Özer N, Guc D, Aytemir K, Tokgözoğlu L. The association between serum angiogenin and osteopontin levels and coronary collateral circulation in patients with chronic total occlusion. Anatol J Cardiol 2019; 22: 77-84
24.Gok Yavuz B, Gunaydin G, Gedik ME, Kosemehmetoglu K, Karakoc D, Ozgur F, GucD. Cancer associated fibroblasts sculpt tumour microenvironment by recruitingmonocytes and inducing immunosuppressive TAMs. Sci Rep. 2019Feb 28;9(1):3172. doi: 10.1038/s41598-019-39553-z. PMID: 30816272;
25. Turan IS, Gunaydin G, Ayan S, Akkaya EU. Molecular demultiplexer as aterminator automaton. Nat Commun. 2018 Feb 23;9(1):805. doi:10.1038/s41467-018-03259-z. PMID: 29476048;
26. Karaman O, Almammadov T, Emre Gedik M, Gunaydin G, Kolemen S, Gunbas G.Mitochondria-Targeting Selenophene-Modified BODIPY-Based Photosensitizers forthe Treatment of Hypoxic Cancer Cells. ChemMedChem. 2019 Nov20;14(22):1879-1886. doi: 10.1002/cmdc.201900380. Epub 2019 Nov 5.
27. Gok Yavuz B, Gunaydin G, Kosemehmetoglu K, Karakoc D, Ozgur F, Guc D. The effects of cancer-associated fibroblasts obtained from atypical ductalhyperplasia on anti-tumor immune responses. Breast J. 2018 Nov;24(6):1099-1101.doi: 10.1111/tbj.13139. Epub 2018 Sep 27. PMID: 30264475.
28.. Dolen Y, Gunaydin G, Esendagli G, Guc D. Granulocytic subset of myeloid derived suppressor cells in rats with mammary carcinoma. Cell Immunol. 2015May;295(1):29-35. doi: 10.1016/j.cellimm.2015.02.005. Epub 2015 Feb 18.
29.. Ayan S, Gunaydin G, Yesilgul-Mehmetcik N, Gedik ME, Seven O, Akkaya EU. Proof-of-principle for two-stage photodynamic therapy: hypoxia triggered release of singlet oxygen. Chem Commun (Camb). 2020 Nov 26;56(94):14793-14796. doi:10.1039/d0cc06031c. PMID: 33196713.
30.. Turan IS, Yildiz D, Turksoy A, Gunaydin G, Akkaya EU. A Bifunctional Photosensitizer for Enhanced Fractional Photodynamic Therapy: Singlet OxygenGeneration in the Presence and Absence of Light. Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2875-8. doi: 10.1002/anie.201511345. Epub 2016 Jan 22
31. Gunaydin G, Kesikli SA, Guc D. Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novelMDSC subset. Oncoimmunology. 2015 May 27;4(9):e1034918. doi:10.1080/2162402X.2015.1034918. PMID: 26405600; PMCID: PMC4570137.
32. Ozmen F, Şahin TT, Ozmen MM. Current adjuvant therapeutic approaches forpancreatic cancer. Adv Ther. 2015 Jan;32(1):42-56. doi:10.1007/s12325-015-0177-5. Epub 2015 Jan 17. PMID: 25595483.
33 Esendagli D, Ozmen F, Koksal D, Onder S, Emri S. Association of class IIhuman leukocyte antigen (HLA) alleles with pulmonary sarcoidosis. SarcoidosisVasc Diffuse Lung Dis. 2018;35(2):143-149. doi: 10.36141/svdld.v35i2.6455. Epub2018 Apr 28. PMID: 32476894; PMCID: PMC7170083.
34 Ozmen F. Response letter regarding the interpretation of gene expressiondata. World J Gastroenterol. 2013 Mar 14;19(10):1669-70. doi:10.3748/wjg.v19.i10.1669. PMID: 23539643; PMCID: PMC3602488.
35. Ozmen MM, Ozmen F, Zulfikaroglu B. Lymph nodes in gastric cancer. J SurgOncol. 2008 Nov 1;98(6):476-81. doi: 10.1002/jso.21134. PMID: 18720367.
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