Medical Microbiology Department Virology Laboratory

About

After Hacettepe University was founded in 1967, Virology Research Laboratory established by Prof. Dr. Şemsettin Ustaçelebi. Between 2008-2018 the director of the Virology Laboratory was Prof. Dr. Dürdal Us. Since 2018 the laboratory is conducted by  Prof. Dr. Ahmet Pınar. Our laboratory, which also provides Medical Virology subspecialty training, conducts scientific research on vector-borne viruses, rodent-borne viruses, viruses that cause neurological diseases and respiratory tract viruses. Studies focus on molecular and serological diagnosis, vector/reservoir-host interaction, epidemiology and ecology of pathogens, identification of new viruses and molecular evolution. The Virology part of the Medical Microbiology Specialization Training is also provided in our laboratory.

Research Infrastructure

    • Class II Biosafety Cabinet (2 Units)
    • Inverted Microscope (1 Unit)
    • Thermal Cycle Device (2 Units)
    • Microcentrifuge (2 Units)
    • Vortex (2 Units)
    • Heat Block (1 Unit)
    • Refrigerator +4 (4 Units)
    • Deep Freezer -20 (2 Units)
    • Deep Freezer -80 (1 Unit)
    • Computer (2 Units)

Researchers

•    Prof. Ahmet Pınar, M.D. Ph.D
•    Prof. Koray Ergünay, M.D. Ph.D
•    Assist Prof. Ceylan Polat, Ph.D.

Projects

1- GEIS Research Project Award “Identification and incrimination of mosquito and sand fly vectors of viral diseases and pathogens present in refugee zones of the Turkish and Jordanian borders with Syria” Alten B, Günay F, Ergünay K., et al . 2015 - Internationally supported scientific research project other than EU Framework Program/NIH/NSF/ERC scientific research projects.

2- Evaluation of seasonal distribution of Orthohantaviruses by rodent monitorization. Polat C, Erdin M, Kalkan O, Irmak S, Öktem MA, et al. 2015 TUBİTAK 1001 Project.

3- Lymphocytic choriomeningitidis virus: Host diversity and phylogeographic diffusion. Polat C, Öktem MA, Erdin M, Sironen T, et al. 2015

4-  Screening and Genotyping of Chronic Hepatitis C Acute Hepatitis Hematopoietic Stem Cell Transplantation Kidney Transplantation Hepatitis E Virus in High Risk Patient Groups, Balaban HY, Alp A., Hasçelik AG, Pürnak T, Ergünay K, Dağ O., et al ., Project Supported by Higher Education Institutions, 2019

5- Determination of Human Parechovirus Prevalence in Newborn and Pediatric Patients. Özdemir A, Aliyev F, Polat C, Çelik HT, Özsürekçi Y, Ergünay K, Pınar A. 2021 HÜBAP Career Support Project

6- Molecular Epidemiological Analysis of HIV-1 Infection in Anatolia and Examination of the Antiretroviral Drug Resistance Profile. Özdemir A, Uzun M, Polat C, Sönmezer MÇ, Demir T, İnkaya AÇ, Ergünay K, Ünal S, Pınar A. 2021 Gilead Ideas That Come to Life Project

7- RNA virome in Hyalomma scupense and Rhipicephalus bursa species. Özdemir A, Polat C, Ergünay K, Pınar A, Erdin M, Sironen T, et al. 2021.

8- EU Horizon CLIMOS Project 2021 Kasap ÖE, Oğuz G, Polat C, Alten B, Ergünay K

9- Investigation of Ganciclovir resistance in Cytomegalovirus strains detected in patients with primary and secondary immunodeficiency by genotypic methods. Fırtına A, Polat C, Alp A, İnkaya AÇ, Özsürekçi Y, Pınar A. 2022 HÜBAP Quick Support Project.

10- Genomic Characterization of Mosquito-Borne Flaviviruses Circulating in Turkey. Sewade WT, Kasap ÖE, Polat C, Alten B. 2022 Overseas Turks and Related Communities Doctoral Thesis Project.

Completed Projects

• Evaluation of the Relationship Between Intestinal Microbiota and Metabolic Parameters in Patients Undergoing Bariatric Surgery, BÜYÜKTUNCER DEMİREL Z. (Executive), ERGÜNAY K., DOĞRUMAN AL F., TURHAN T., YILDIZ BD, YOZGAT A., et al., Higher Education Institutions Supported Project , 2019 – 2020
• Vector Induced Viral Infections in Guillain-Barre Patients, ERGÜNAY K. (Coordinator), ERDEM ÖZDAMAR S., KURT C. E., Higher Education Institutions Supported Project, 2017 – 2020
• The Role of Intestinal Microbiota in the Pathogenesis of Various Diseases, AKYÖN YILMAZ Y. (Executive), BOZDAĞ G., ERDOĞDU C., YILDIZ O. B., DURSUN E., ERGÜNAY K., et al., Higher Education Institutions Supported Project, 2017 - 2020
• Hard Tick (Acari: Ixodidae) Fauna in Turkey, Geographical Distribution and Vectorial Roles Points, HEKİMOĞLU O. (Executive), ERGÜNAY K., Higher Education Institutions Supported Project, 2017 - 2019
• Evaluation and current findings of mosquito-borne Flaviviruses in Anatolia and Thrace in the last 10 years, ERGÜNAY K. (Executive), Higher Education Institutions Supported Project, 2017 – 2017
• Detection of Chikungunya virus in field-borne mosquitoes for the first time in addition to West Nile and mosquito Flaviviruses in the Mediterranean, Aegean and Thrace regions of Turkey, ERGÜNAY K. (Executive), Higher Education Institutions Supported Project, 2016 – 2016

Publications

1- Karadag-Oncel E, Gonc N, Altay O, Cengiz AB, Ozon A, Pinar A, Ceyhan M, Alikasifoglu A, Akyon Y, Kandemir N, Ozsurekci Y, Kara A. Prevalence of nasal carriage of methicillin-resistant Staphylococcus aureus in children with diabetes mellitus: Trends between 2005 and 2013. Am J Infect Control. 2015 Sep 1;43(9):1015-7. doi: 10.1016/j.ajic.2015.04.206. Epub 2015 Jun 3.

 

2-  Aydın NN, Ergünay K, Karagül A, Pınar A, Us D. Investigation of the Hepatitis E Virus Seroprevalence in Cases Admitted to Hacettepe University Medical Faculty Hospital Mikrobiyol Bul. 2015 Oct;49(4):554-64. doi: 10.5578/mb.9881

 

3- Kayman T, Polat C, Ergör G, Abacıoğlu H. Characterization of HCV genotype 4d infections in Kayseri, Turkey. Turk J Med Sci 2015; 45: 547-52.


4- Ergunay K, Tkachev S, Kozlova I, Ruzek D. A Review of Methods for Detecting Tick-Borne Encephalitis Virus Infection in Tick, Animal, and Human Specimens. Vector-Borne and Zoonotic Diseases. 2016; 16(1):4-12.


5- Polat C, Karatas A, Sözen M, Matur F, Abacioglu H, Oktem MA. Optimization of ELISA and Immunoblot Methods for the Detection of IgG Antibodies Against Old World Hantaviruses in Wild Rodents. Mikrobiyol Bul 2016; 50(2): 245-55.


6- Dincer E, Karapinar Z, Oktem M, Ozbaba M, Ozkul A, Ergunay K. Canine infections and partial S segment sequence analysis of Toscana virus in Turkey. Vector-Borne and Zoonotic Diseases. 2016; 16(9):611-8.


7- Ergunay K, Ayhan N, Charrel RN. Novel and emergent sandfly-borne phleboviruses in Asia Minor: a systematic review. Reviews In Medical Virology. 2017;27(2): doi: 10.1002/rmv.1898


8- Demir ZC, Bastug A, Bodur H, Ergunay K, Ozkul A. MicroRNA expression profiles in patients with acute Crimean Congo hemorrhagic fever reveal possible adjustments to cellular pathways. Journal of Medical Virology. 2017; 89(3):417-22.


9- Ergünay K, Litzba N, Brinkmann A, Günay F, Kar S, Öter K, Örsten S, Sarıkaya Y, Alten B, Nitsche A, Linton YM. Isolation and genomic characterization of Culex theileri flaviviruses in field-collected mosquitoes from Turkey. Infection, Genetics and Evolution. 2016; 46:138-47.


10- Ayhan N, Baklouti A, Prudhomme J, Walder G, Amaro F, Alten B, Moutailler S, Ergunay K, Charrel RN, Huemer H. Practical Guidelines for Studies on Sandfly-Borne Phleboviruses: Part I: Important Points to Consider Ante Field Work. Vector-Borne and Zoonotic Diseases. 2017;17(1):73-80.


11- Huemer H, Prudhomme J, Amaro F, Baklouti A, Walder G, Alten B, Moutailler S, Ergunay K, Charrel RN, Ayhan N. Practical Guidelines for Studies on Sandfly-Borne Phleboviruses: Part II: Important Points to Consider for Fieldwork and Subsequent Virological Screening. Vector-Borne and Zoonotic Diseases. 2017;17(1):81-90.


12- Altay Koçak A, Öcal M, Polat M, Kanık Yüksek S, Aktaş Tapısız A, Tezer H, Özkul A, Ergünay K, Bozdayı G, Ahmed K. Multicenter investigation of bufavirus in the etiology of viral central nervous system infections of adults and children. Mikrobiyoloji Bülteni. 2017; 51(2):191-4.


13- Tüney İ, Altay A, Ergünay K, Önder SÇ, Usubütün A, Salman MC, Bozdayi G, Karabulut E, Badur OS, Yüce K, Pinar A. HPV types and E6/E7 mRNA expression in cervical samples from Turkish women with abnormal cytology in Ankara, Turkey. Turkish Journal of Medical Sciences. 2017; 47(1):194-200.


14- Ergünay K, Litzba N, Brinkmann A, Günay F, Sarıkaya Y, Kar S, Örsten S, Öter K, Domingo C, Erisoz Kasap Ö, Özkul A, Mitchell L, Nitsche A, Alten B, Linton YM. Co-circulation of West Nile virus and distinct insect-specific flaviviruses in Turkey. Parasites and Vectors. 2017; 10(1):149.


15- Ergünay K, Brinkmann A, Litzba N, Günay F, Kar S, Öter K, Örsten S, Sarıkaya Y, Alten B, Nitsche A, Linton YM. A novel rhabdovirus, related to Merida virus, in field-collected mosquitoes from Anatolia and Thrace. Archives of Virology. 2017; 162(7):1903-11.


16- Dinçer E, Brinkmann A, Hekimoğlu O, Hacıoğlu S, Földes K, Karapınar Z, Polat PF, Oğuz B, Orunç Kılınç Ö, Hagedorn P, Özer N, Özkul A, Nitsche A, Ergünay K. Generic amplification and next generation sequencing reveal Crimean-Congo hemorrhagic fever virus AP92-like strain and distinct tick phleboviruses in Anatolia, Turkey. Parasites and Vectors. 2017;10(1):335


17- Hacioglu S, Dincer E, Tayer Isler C, Karapinar Z, Ataseven VS, Ozkul A, Ergunay K. A snapshot avian surveillance reveals West Nile virus and evidence of wild birds participating in Toscana virus circulation. Vector-Borne and Zoonotic Diseases. 2017; 17(10):698-708


18- Öncü C, Brinkmann A, Günay F, Kar S, Öter K, Sarıkaya Y, Nitsche A, Linton YM, Alten B, Ergünay K. West Nile virus, Anopheles flavivirus, a novel flavivirus as well as Merida-like rhabdovirus Turkey in field-collected mosquitoes from Thrace and Anatolia. Infect Genet Evol. 2018; 57:36-45.


19- Brinkmann A, Ergünay K, Radonić A, Kocak Tufan Z, Domingo C, Nitsche A. Development and preliminary evaluation of a multiplexed amplification and next generation sequencing method for viral hemorrhagic fever diagnostics. PLoS Negl Trop Dis. 2017; 11(11):e0006075


20- Polat C, Matur F, Sözen M, Oktem MA. Türkiye’nin Orta ve Güney Anadolu illerindeki yabani kemiricilerde hantavirüs enfeksiyonlarının serolojik olarak taranması. Türk Mikrobiyol Cem Derg 2017; 47(1): 6-10.


21- Brinkmann A, Dinçer E, Polat C, Hekimoğlu O, Hacıoğlu S, Földes K, Özkul A, Öktem İMA, Nitsche A, Ergünay K. A metagenomic survey identifies Tamdy orthonairovirus as well as divergent phlebo-, rhabdo-, chu- and flavi-like viruses in Anatolia, Turkey. Ticks Tick Borne Dis. 2018; 9(5):1173-1183
22- Polat C, Sironen T, Plyusnina A, Karatas A, Sozen M, Matur F, Vapalahti O, Oktem IMA, Plyusnin A. Dobrava hantavirus variants found in Apodemus flavicollis mice in Kırklareli province, Turkey. J Med Virol 2018, 90(5): 810-8.


23- Polat C, Ergünay K, Irmak S, Erdin M, Brinkmann A, Çetintaş O, Çoğal M, Sözen M, Matur F, Nitsche A, Öktem İMA. A novel genetic lineage of Tula orthohantavirus in Altai voles (Microtus obscurus) from Turkey. Infect Genet Evol. 2019; 67:150-158.


24- Brinkmann A, Hekimoğlu O, Dinçer E, Hagedorn P, Nitsche A, Ergünay K. A cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia. Parasit Vectors. 2019;12(1):26.


25- Aligholipour Farzani T, Hanifehnezhad A, Földes K, Ergünay K, Yilmaz E, Hashim Mohamed Ali H, Ozkul A. Co-Delivery Effect of CD24 on the Immunogenicity and Lethal Challenge Protection of a DNA Vector Expressing Nucleocapsid Protein of Crimean Congo Hemorrhagic Fever Virus. Viruses. 2019;11(1). pii: E75.


26- Maes P, Adkins S, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, DeRisi JL, Digiaro M, Drebot M, Ebihara H, Elbeaino T, Ergünay K, et al. Taxonomy of the order Bunyavirales: second update 2018. Arch Virol. 2019; 164(3):927-941


27- Aligholipour Farzani T, Földes K, Hanifehnezhad A, Yener Ilce B, Bilge Dagalp S, Amirzadeh Khiabani N, Ergünay K, Alkan F, Karaoglu T, Bodur H, Ozkul A. Bovine Herpesvirus Type 4 (BoHV-4) Vector Delivering Nucleocapsid Protein of Crimean-Congo Hemorrhagic Fever Virus Induces Comparable Protective Immunity against Lethal Challenge in IFNα/β/γR-/- Mice Models. Viruses. 2019;11(3). pii: E237.


28- Akıner MM, Öztürk M, Başer AB, Günay F, Hacıoğlu S, Brinkmann A, Emanet N, Alten B, Özkul A, Nitsche A, Linton YM, Ergünay K. Arboviral screening of invasive Aedes species in northeastern Turkey: West Nile virus circulation and detection of insect-only viruses. PLoS Negl Trop Dis. 2019; 13(5):e0007334.


29- Emanet N, Kar S, Dinçer E, Brinkmann A, Hacıoğlu S, Farzani TA, Koçak Tufan Z, Polat PF, Şahan A, Özkul A, Nitsche A, Linton YM, Ergünay K. Novel Tick Phlebovirus Genotypes Lacking Evidence for Vertebrate Infections in Anatolia and Thrace, Turkey. Viruses. 2019; 11(8). pii: E703.


30- Bellikci-Koyu E, Sarer-Yurekli BP, Akyon Y, Aydin-Kose F, Karagozlu C, Ozgen AG, Brinkmann A, Nitsche A, Ergunay K, Yilmaz E, Buyuktuncer Z. Effects of Regular Kefir Consumption on Gut Microbiota in Patients with Metabolic Syndrome: A Parallel-Group, Randomized, Controlled Study. Nutrients. 2019; 11(9). pii: E2089.


31- Aligholipour Farzani T, Földes K, Ergünay K, Gurdal H, Bastug A, Ozkul A. Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse Models. Vaccines (Basel). 2019; 7(3). pii: E115.


32- Abudurexiti A, Adkins S, Alioto D, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Cháng C, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, Dèng F, Di Serio F, Digiaro M, Drebot MA, Duàn X, Ebihara H, Elbeaino T, Ergünay K, et al. Taxonomy of the order Bunyavirales: update 2019. Arch Virol. 2019; 164(7):1949-1965.


33- Dinçer E, Hacıoğlu S, Kar S, Emanet N, Brinkmann A, Nitsche A, Özkul A, Linton YM, Ergünay K. Survey and Characterization of Jingmen Tick Virus Variants. Viruses. 2019; 11(11). doi: 10.3390/v11111071.


34- Özbel Y, Oğuz G, Arserim SK, Erişöz Kasap Ö, Karaoglu B, Yilmaz A, Emanet N, Günay F, Hacioğlu S, Demirok MC, Töz S, Alten B, Nalçaci M, Özkul A, Ergünay K. The initial detection of Toscana virus in phlebotomine sandflies from Turkey. Med Vet Entomol. 2020; 34(4):402-410.


35- Ergünay K. Revisiting new tick-associated viruses: what comes next?. Future Virol. 2020; 15(1): doi:10.2217/fvl-2019-0149


36- Okar SV, Bekircan-Kurt CE, Hacıoğlu S, Erdem-Özdamar S, Özkul A, Ergünay K. Toscana virus associated with Guillain-Barré syndrome: a case-control study. Acta Neurol Belg. 2020; doi: 10.1007/s13760-020-01279-5.


37- Altay-Kocak A, Bozdayi G, Michel J, Polat M, Kanik-Yuksek S, Tezer H, Ozkul A, Ahmed K, Nitsche A, Ergunay K. Multi-assay investigation of viral etiology in pediatric central nervous system infections. J Infect Dev Ctries. 2020;14(6):572-579.


38- Kuhn JH, Adkins S, Alioto D, Alkhovsky SV, Amarasinghe GK, Anthony SJ, Avšič-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bartonička T, Basler C, Bavari S, Beer M, Bente DA, Bergeron É, Bird BH, Blair C, Blasdell KR, Bradfute SB, Breyta R, Briese T, Brown PA, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Buzkan N, Calisher CH, Cao M, Casas I, Chamberlain J, Chandran K, Charrel RN, Chen B, Chiumenti M, Choi IR, Clegg JCS, Crozier I, da Graça JV, Dal Bó E, Dávila AMR, de la Torre JC, de Lamballerie X, de Swart RL, Di Bello PL, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolja VV, Dolnik O, Drebot MA, Drexler JF, Dürrwald R, Dufkova L, Dundon WG, Duprex WP, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K,et al. 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2020; 165(12):3023-3072. doi: 10.1007/s00705-020-04731-2.


39- Ergünay K, Dinçer E, Kar S, Emanet N, Yalçınkaya D, Polat Dinçer PF, Brinkmann A, Hacıoğlu S, Nitsche A, Özkul A, Linton YM. Multiple orthonairoviruses including Crimean-Congo hemorrhagic fever virus, Tamdy virus and the novel Meram virus in Anatolia. Ticks Tick Borne Dis. 2020; 11(5):101448.


40- Földes K, Aligholipour Farzani T, Ergünay K, Ozkul A. Differential Growth Characteristics of Crimean-Congo Hemorrhagic Fever Virus in Kidney Cells of Human and Bovine Origin. Viruses. 2020 Jun 25;12(6). doi: 10.3390/v12060685.


41- Eyupoglu ND, Ergunay K, Acikgoz A, Akyon Y, Yilmaz E, Yildiz BO. Gut Microbiota and Oral Contraceptive Use in Overweight and Obese Patients with Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2020;105(12). doi: 10.1210/clinem/dgaa600.


42- Örsten S, Demirci-Duarte S, Ünalan-Altıntop T, Çakar A, Sancak B, Ergünay K, Özkuyumcu C. Low prevalence of hypervirulent Klebsiella pneumoniae in Anatolia, screened via phenotypic and genotypic testing. Acta Microbiol Immunol Hung. 2020;. doi: 10.1556/030.2020.01143.


43- Garrison AR, Alkhovsky Альховский Сергей Владимирович SV, Avšič-Županc T, Bente DA, Bergeron É, Burt F, Di Paola N, Ergünay K, Hewson R, Kuhn JH, Mirazimi A, Papa A, Sall AA, Spengler JR, Palacios G, Consortium IR. ICTV Virus Taxonomy Profile: Nairoviridae. J Gen Virol. 2020; 101(8):798-799.


44- Hanifehnezhad A, Kehribar EŞ, Öztop S, Sheraz A, Kasırga S, Ergünay K, Önder S, Yılmaz E, Engin D, Oğuzoğlu TÇ, Şeker UÖŞ, Yılmaz E, Özkul A. Characterization of local SARS-CoV-2 isolates and pathogenicity in IFNAR-/- mice. Heliyon. 2020; 6(9):e05116. doi: 10.1016/j.heliyon.2020.e05116.


45- Ergünay K, Polat C, Özkul A. Vector-borne viruses in Turkey: A systematic review and bibliography. Antiviral Res. 2020; 183:104934. doi: 10.1016/j.antiviral.2020.104934

.
46- Polat C, Ergin Ç, Akkaya Y, Oktem IMA. Investigation of Orthohantavirus seroprevalence in northern rural areas of Denizli province, Turkey. Jpn J Infect Dis 2020; 73(3): 201-204.

 

47- Unalan-Altintop, T., Vahabov, C., Ergunay, K., Kurt, O., Kav, T., Akyon, Y., Erguven, S Investigation of Dientamoeba fragilis and Blastocystis in patients from Turkey with ulcerative colitis and irritable bowel syndrome: Any relation with genotypes? Acta Tropica, 2022; 231, art. no. 106451.

 

48- Kamau J, Ergunay K, Webala PW, Justi SA, Bourke BP, Kamau MW, Hassell J, Chege MN, Mwaura DK, Simiyu C, Kibiwot S, Onyuok S, Caicedo-Quiroga L, Li T, Zimmerman DM, Linton YM. A Novel Coronavirus and a Broad Range of Viruses in Kenyan Cave Bats. Viruses. 2022 Dec 17;14(12):2820.

 

49- Kuhn JH, Adkins S, Alkhovsky SV, Avšič-Županc T, Ayllón MA, Bahl J, Balkema- Buschmann A, Ballinger MJ, Bandte M, Beer M, Bejerman N, Bergeron É, Biedenkopf N, Bigarré L, Blair CD, Blasdell KR, Bradfute SB, Briese T, Brown PA, Bruggmann R, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Candresse T, Carson J, Casas I, Chandran K, Charrel RN, Chiaki Y, Crane A, Crane M, Dacheux L, Bó ED, de la Torre JC, de Lamballerie X, de Souza WM, de Swart RL, Dheilly NM, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Drexler JF, Duprex WP, Dürrwald R, Easton AJ, Elbeaino T, Ergünay K, et al. 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2022 Dec;167(12):2857-2906.

 

50- Balaban HY, Aslan AT, Akdoğan-Kittana FN, Alp A, Dağ O, Ayar ŞN, Vahabov C, Şimşek C, Yıldırım T, Göker H, Ergünay K, Erdem Y, Büyükaşık Y, Şimşek H. Hepatitis E Virus Prevalence and Associated Risk Factors in High-Risk Groups: A Cross-Sectional Study. Turk J Gastroenterol. 2022 Jul;33(7):615-624.

 

51- Ergunay K, Mutinda M, Bourke B, Justi SA, Caicedo-Quiroga L, Kamau J, Mutura S, Akunda IK, Cook E, Gakuya F, Omondi P, Murray S, Zimmerman D, Linton YM. Metagenomic Investigation of Ticks From Kenyan Wildlife Reveals Diverse Microbial Pathogens and New Country Pathogen Records. Front Microbiol. 2022 Jul 1;13:932224.

 

52- Ahan RE, Hanifehnezhad A, Kehribar EŞ, Oguzoglu TC, Földes K, Özçelik CE, Filazi N, Öztop S, Palaz F, Önder S, Bozkurt EU, Ergünay K, Özkul A, Şeker UÖŞ. A Highly Potent SARS-CoV-2 Blocking Lectin Protein. ACS Infect Dis. 2022 Jul 8;8(7):1253-1264.

 

53- Papa A, Marklewitz M, Paraskevopoulou S, Garrison AR, Alkhovsky SV, Avšič- Županc T, Bente DA, Bergeron É, Burt F, Di Paola N, Ergünay K, Hewson R, Mirazimi A, et al. History and classification of Aigai virus (formerly Crimean-Congo haemorrhagic fever virus genotype VI). J Gen Virol. 2022 Apr;103(4):001734.

 

54- Dinçer E, Timurkan MÖ, Oğuz B, Şahindokuyucu İ, Şahan A, Ekinci M, Polat C, Ergünay K. Several Tick-Borne Pathogenic Viruses in Circulation in Anatolia, Turkey. Vector Borne Zoonotic Dis. 2022 Feb;22(2):148-158.

 

55- Gökahmetoğlu S, Polat C, Atalay MA, Sezgin GC, Ergör G, Aygen B, Gürsoy Ş, Abacıoğlu YH. Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turk J Gastroenterol 2022. doi: 10.5152/tjg.2022.21822.

 

56- Ergunay K, Dincer E, Justi SA, Bourke BP, Nelson SP, Liao HM, Timurkan MO, Oguz B, Sahindokuyucu I, Gokcecik OF, Reinbold-Wasson DD, Jiang L, Achee NL, Grieco JP, Linton YM. Impact of nanopore-based metagenome sequencing on tick- borne virus detection. Front Microbiol. 2023 May 30;14:1177651.

About

After Hacettepe University was founded in 1967, Virology Research Laboratory established by Prof. Dr. Şemsettin Ustaçelebi. Between 2008-2018 the director of the Virology Laboratory was Prof. Dr. Dürdal Us. Since 2018 the laboratory is conducted by  Prof. Dr. Ahmet Pınar. Our laboratory, which also provides Medical Virology subspecialty training, conducts scientific research on vector-borne viruses, rodent-borne viruses, viruses that cause neurological diseases and respiratory tract viruses. Studies focus on molecular and serological diagnosis, vector/reservoir-host interaction, epidemiology and ecology of pathogens, identification of new viruses and molecular evolution. The Virology part of the Medical Microbiology Specialization Training is also provided in our laboratory.

Research Infrastructure

    • Class II Biosafety Cabinet (2 Units)
    • Inverted Microscope (1 Unit)
    • Thermal Cycle Device (2 Units)
    • Microcentrifuge (2 Units)
    • Vortex (2 Units)
    • Heat Block (1 Unit)
    • Refrigerator +4 (4 Units)
    • Deep Freezer -20 (2 Units)
    • Deep Freezer -80 (1 Unit)
    • Computer (2 Units)

Researchers

•    Prof. Ahmet Pınar, M.D. Ph.D
•    Prof. Koray Ergünay, M.D. Ph.D
•    Assist Prof. Ceylan Polat, Ph.D.

Projects

1- GEIS Research Project Award “Identification and incrimination of mosquito and sand fly vectors of viral diseases and pathogens present in refugee zones of the Turkish and Jordanian borders with Syria” Alten B, Günay F, Ergünay K., et al . 2015 - Internationally supported scientific research project other than EU Framework Program/NIH/NSF/ERC scientific research projects.

2- Evaluation of seasonal distribution of Orthohantaviruses by rodent monitorization. Polat C, Erdin M, Kalkan O, Irmak S, Öktem MA, et al. 2015 TUBİTAK 1001 Project.

3- Lymphocytic choriomeningitidis virus: Host diversity and phylogeographic diffusion. Polat C, Öktem MA, Erdin M, Sironen T, et al. 2015

4-  Screening and Genotyping of Chronic Hepatitis C Acute Hepatitis Hematopoietic Stem Cell Transplantation Kidney Transplantation Hepatitis E Virus in High Risk Patient Groups, Balaban HY, Alp A., Hasçelik AG, Pürnak T, Ergünay K, Dağ O., et al ., Project Supported by Higher Education Institutions, 2019

5- Determination of Human Parechovirus Prevalence in Newborn and Pediatric Patients. Özdemir A, Aliyev F, Polat C, Çelik HT, Özsürekçi Y, Ergünay K, Pınar A. 2021 HÜBAP Career Support Project

6- Molecular Epidemiological Analysis of HIV-1 Infection in Anatolia and Examination of the Antiretroviral Drug Resistance Profile. Özdemir A, Uzun M, Polat C, Sönmezer MÇ, Demir T, İnkaya AÇ, Ergünay K, Ünal S, Pınar A. 2021 Gilead Ideas That Come to Life Project

7- RNA virome in Hyalomma scupense and Rhipicephalus bursa species. Özdemir A, Polat C, Ergünay K, Pınar A, Erdin M, Sironen T, et al. 2021.

8- EU Horizon CLIMOS Project 2021 Kasap ÖE, Oğuz G, Polat C, Alten B, Ergünay K

9- Investigation of Ganciclovir resistance in Cytomegalovirus strains detected in patients with primary and secondary immunodeficiency by genotypic methods. Fırtına A, Polat C, Alp A, İnkaya AÇ, Özsürekçi Y, Pınar A. 2022 HÜBAP Quick Support Project.

10- Genomic Characterization of Mosquito-Borne Flaviviruses Circulating in Turkey. Sewade WT, Kasap ÖE, Polat C, Alten B. 2022 Overseas Turks and Related Communities Doctoral Thesis Project.

Completed Projects

• Evaluation of the Relationship Between Intestinal Microbiota and Metabolic Parameters in Patients Undergoing Bariatric Surgery, BÜYÜKTUNCER DEMİREL Z. (Executive), ERGÜNAY K., DOĞRUMAN AL F., TURHAN T., YILDIZ BD, YOZGAT A., et al., Higher Education Institutions Supported Project , 2019 – 2020
• Vector Induced Viral Infections in Guillain-Barre Patients, ERGÜNAY K. (Coordinator), ERDEM ÖZDAMAR S., KURT C. E., Higher Education Institutions Supported Project, 2017 – 2020
• The Role of Intestinal Microbiota in the Pathogenesis of Various Diseases, AKYÖN YILMAZ Y. (Executive), BOZDAĞ G., ERDOĞDU C., YILDIZ O. B., DURSUN E., ERGÜNAY K., et al., Higher Education Institutions Supported Project, 2017 - 2020
• Hard Tick (Acari: Ixodidae) Fauna in Turkey, Geographical Distribution and Vectorial Roles Points, HEKİMOĞLU O. (Executive), ERGÜNAY K., Higher Education Institutions Supported Project, 2017 - 2019
• Evaluation and current findings of mosquito-borne Flaviviruses in Anatolia and Thrace in the last 10 years, ERGÜNAY K. (Executive), Higher Education Institutions Supported Project, 2017 – 2017
• Detection of Chikungunya virus in field-borne mosquitoes for the first time in addition to West Nile and mosquito Flaviviruses in the Mediterranean, Aegean and Thrace regions of Turkey, ERGÜNAY K. (Executive), Higher Education Institutions Supported Project, 2016 – 2016

Publications

1- Karadag-Oncel E, Gonc N, Altay O, Cengiz AB, Ozon A, Pinar A, Ceyhan M, Alikasifoglu A, Akyon Y, Kandemir N, Ozsurekci Y, Kara A. Prevalence of nasal carriage of methicillin-resistant Staphylococcus aureus in children with diabetes mellitus: Trends between 2005 and 2013. Am J Infect Control. 2015 Sep 1;43(9):1015-7. doi: 10.1016/j.ajic.2015.04.206. Epub 2015 Jun 3.

 

2-  Aydın NN, Ergünay K, Karagül A, Pınar A, Us D. Investigation of the Hepatitis E Virus Seroprevalence in Cases Admitted to Hacettepe University Medical Faculty Hospital Mikrobiyol Bul. 2015 Oct;49(4):554-64. doi: 10.5578/mb.9881

 

3- Kayman T, Polat C, Ergör G, Abacıoğlu H. Characterization of HCV genotype 4d infections in Kayseri, Turkey. Turk J Med Sci 2015; 45: 547-52.


4- Ergunay K, Tkachev S, Kozlova I, Ruzek D. A Review of Methods for Detecting Tick-Borne Encephalitis Virus Infection in Tick, Animal, and Human Specimens. Vector-Borne and Zoonotic Diseases. 2016; 16(1):4-12.


5- Polat C, Karatas A, Sözen M, Matur F, Abacioglu H, Oktem MA. Optimization of ELISA and Immunoblot Methods for the Detection of IgG Antibodies Against Old World Hantaviruses in Wild Rodents. Mikrobiyol Bul 2016; 50(2): 245-55.


6- Dincer E, Karapinar Z, Oktem M, Ozbaba M, Ozkul A, Ergunay K. Canine infections and partial S segment sequence analysis of Toscana virus in Turkey. Vector-Borne and Zoonotic Diseases. 2016; 16(9):611-8.


7- Ergunay K, Ayhan N, Charrel RN. Novel and emergent sandfly-borne phleboviruses in Asia Minor: a systematic review. Reviews In Medical Virology. 2017;27(2): doi: 10.1002/rmv.1898


8- Demir ZC, Bastug A, Bodur H, Ergunay K, Ozkul A. MicroRNA expression profiles in patients with acute Crimean Congo hemorrhagic fever reveal possible adjustments to cellular pathways. Journal of Medical Virology. 2017; 89(3):417-22.


9- Ergünay K, Litzba N, Brinkmann A, Günay F, Kar S, Öter K, Örsten S, Sarıkaya Y, Alten B, Nitsche A, Linton YM. Isolation and genomic characterization of Culex theileri flaviviruses in field-collected mosquitoes from Turkey. Infection, Genetics and Evolution. 2016; 46:138-47.


10- Ayhan N, Baklouti A, Prudhomme J, Walder G, Amaro F, Alten B, Moutailler S, Ergunay K, Charrel RN, Huemer H. Practical Guidelines for Studies on Sandfly-Borne Phleboviruses: Part I: Important Points to Consider Ante Field Work. Vector-Borne and Zoonotic Diseases. 2017;17(1):73-80.


11- Huemer H, Prudhomme J, Amaro F, Baklouti A, Walder G, Alten B, Moutailler S, Ergunay K, Charrel RN, Ayhan N. Practical Guidelines for Studies on Sandfly-Borne Phleboviruses: Part II: Important Points to Consider for Fieldwork and Subsequent Virological Screening. Vector-Borne and Zoonotic Diseases. 2017;17(1):81-90.


12- Altay Koçak A, Öcal M, Polat M, Kanık Yüksek S, Aktaş Tapısız A, Tezer H, Özkul A, Ergünay K, Bozdayı G, Ahmed K. Multicenter investigation of bufavirus in the etiology of viral central nervous system infections of adults and children. Mikrobiyoloji Bülteni. 2017; 51(2):191-4.


13- Tüney İ, Altay A, Ergünay K, Önder SÇ, Usubütün A, Salman MC, Bozdayi G, Karabulut E, Badur OS, Yüce K, Pinar A. HPV types and E6/E7 mRNA expression in cervical samples from Turkish women with abnormal cytology in Ankara, Turkey. Turkish Journal of Medical Sciences. 2017; 47(1):194-200.


14- Ergünay K, Litzba N, Brinkmann A, Günay F, Sarıkaya Y, Kar S, Örsten S, Öter K, Domingo C, Erisoz Kasap Ö, Özkul A, Mitchell L, Nitsche A, Alten B, Linton YM. Co-circulation of West Nile virus and distinct insect-specific flaviviruses in Turkey. Parasites and Vectors. 2017; 10(1):149.


15- Ergünay K, Brinkmann A, Litzba N, Günay F, Kar S, Öter K, Örsten S, Sarıkaya Y, Alten B, Nitsche A, Linton YM. A novel rhabdovirus, related to Merida virus, in field-collected mosquitoes from Anatolia and Thrace. Archives of Virology. 2017; 162(7):1903-11.


16- Dinçer E, Brinkmann A, Hekimoğlu O, Hacıoğlu S, Földes K, Karapınar Z, Polat PF, Oğuz B, Orunç Kılınç Ö, Hagedorn P, Özer N, Özkul A, Nitsche A, Ergünay K. Generic amplification and next generation sequencing reveal Crimean-Congo hemorrhagic fever virus AP92-like strain and distinct tick phleboviruses in Anatolia, Turkey. Parasites and Vectors. 2017;10(1):335


17- Hacioglu S, Dincer E, Tayer Isler C, Karapinar Z, Ataseven VS, Ozkul A, Ergunay K. A snapshot avian surveillance reveals West Nile virus and evidence of wild birds participating in Toscana virus circulation. Vector-Borne and Zoonotic Diseases. 2017; 17(10):698-708


18- Öncü C, Brinkmann A, Günay F, Kar S, Öter K, Sarıkaya Y, Nitsche A, Linton YM, Alten B, Ergünay K. West Nile virus, Anopheles flavivirus, a novel flavivirus as well as Merida-like rhabdovirus Turkey in field-collected mosquitoes from Thrace and Anatolia. Infect Genet Evol. 2018; 57:36-45.


19- Brinkmann A, Ergünay K, Radonić A, Kocak Tufan Z, Domingo C, Nitsche A. Development and preliminary evaluation of a multiplexed amplification and next generation sequencing method for viral hemorrhagic fever diagnostics. PLoS Negl Trop Dis. 2017; 11(11):e0006075


20- Polat C, Matur F, Sözen M, Oktem MA. Türkiye’nin Orta ve Güney Anadolu illerindeki yabani kemiricilerde hantavirüs enfeksiyonlarının serolojik olarak taranması. Türk Mikrobiyol Cem Derg 2017; 47(1): 6-10.


21- Brinkmann A, Dinçer E, Polat C, Hekimoğlu O, Hacıoğlu S, Földes K, Özkul A, Öktem İMA, Nitsche A, Ergünay K. A metagenomic survey identifies Tamdy orthonairovirus as well as divergent phlebo-, rhabdo-, chu- and flavi-like viruses in Anatolia, Turkey. Ticks Tick Borne Dis. 2018; 9(5):1173-1183
22- Polat C, Sironen T, Plyusnina A, Karatas A, Sozen M, Matur F, Vapalahti O, Oktem IMA, Plyusnin A. Dobrava hantavirus variants found in Apodemus flavicollis mice in Kırklareli province, Turkey. J Med Virol 2018, 90(5): 810-8.


23- Polat C, Ergünay K, Irmak S, Erdin M, Brinkmann A, Çetintaş O, Çoğal M, Sözen M, Matur F, Nitsche A, Öktem İMA. A novel genetic lineage of Tula orthohantavirus in Altai voles (Microtus obscurus) from Turkey. Infect Genet Evol. 2019; 67:150-158.


24- Brinkmann A, Hekimoğlu O, Dinçer E, Hagedorn P, Nitsche A, Ergünay K. A cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia. Parasit Vectors. 2019;12(1):26.


25- Aligholipour Farzani T, Hanifehnezhad A, Földes K, Ergünay K, Yilmaz E, Hashim Mohamed Ali H, Ozkul A. Co-Delivery Effect of CD24 on the Immunogenicity and Lethal Challenge Protection of a DNA Vector Expressing Nucleocapsid Protein of Crimean Congo Hemorrhagic Fever Virus. Viruses. 2019;11(1). pii: E75.


26- Maes P, Adkins S, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, DeRisi JL, Digiaro M, Drebot M, Ebihara H, Elbeaino T, Ergünay K, et al. Taxonomy of the order Bunyavirales: second update 2018. Arch Virol. 2019; 164(3):927-941


27- Aligholipour Farzani T, Földes K, Hanifehnezhad A, Yener Ilce B, Bilge Dagalp S, Amirzadeh Khiabani N, Ergünay K, Alkan F, Karaoglu T, Bodur H, Ozkul A. Bovine Herpesvirus Type 4 (BoHV-4) Vector Delivering Nucleocapsid Protein of Crimean-Congo Hemorrhagic Fever Virus Induces Comparable Protective Immunity against Lethal Challenge in IFNα/β/γR-/- Mice Models. Viruses. 2019;11(3). pii: E237.


28- Akıner MM, Öztürk M, Başer AB, Günay F, Hacıoğlu S, Brinkmann A, Emanet N, Alten B, Özkul A, Nitsche A, Linton YM, Ergünay K. Arboviral screening of invasive Aedes species in northeastern Turkey: West Nile virus circulation and detection of insect-only viruses. PLoS Negl Trop Dis. 2019; 13(5):e0007334.


29- Emanet N, Kar S, Dinçer E, Brinkmann A, Hacıoğlu S, Farzani TA, Koçak Tufan Z, Polat PF, Şahan A, Özkul A, Nitsche A, Linton YM, Ergünay K. Novel Tick Phlebovirus Genotypes Lacking Evidence for Vertebrate Infections in Anatolia and Thrace, Turkey. Viruses. 2019; 11(8). pii: E703.


30- Bellikci-Koyu E, Sarer-Yurekli BP, Akyon Y, Aydin-Kose F, Karagozlu C, Ozgen AG, Brinkmann A, Nitsche A, Ergunay K, Yilmaz E, Buyuktuncer Z. Effects of Regular Kefir Consumption on Gut Microbiota in Patients with Metabolic Syndrome: A Parallel-Group, Randomized, Controlled Study. Nutrients. 2019; 11(9). pii: E2089.


31- Aligholipour Farzani T, Földes K, Ergünay K, Gurdal H, Bastug A, Ozkul A. Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse Models. Vaccines (Basel). 2019; 7(3). pii: E115.


32- Abudurexiti A, Adkins S, Alioto D, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Cháng C, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, Dèng F, Di Serio F, Digiaro M, Drebot MA, Duàn X, Ebihara H, Elbeaino T, Ergünay K, et al. Taxonomy of the order Bunyavirales: update 2019. Arch Virol. 2019; 164(7):1949-1965.


33- Dinçer E, Hacıoğlu S, Kar S, Emanet N, Brinkmann A, Nitsche A, Özkul A, Linton YM, Ergünay K. Survey and Characterization of Jingmen Tick Virus Variants. Viruses. 2019; 11(11). doi: 10.3390/v11111071.


34- Özbel Y, Oğuz G, Arserim SK, Erişöz Kasap Ö, Karaoglu B, Yilmaz A, Emanet N, Günay F, Hacioğlu S, Demirok MC, Töz S, Alten B, Nalçaci M, Özkul A, Ergünay K. The initial detection of Toscana virus in phlebotomine sandflies from Turkey. Med Vet Entomol. 2020; 34(4):402-410.


35- Ergünay K. Revisiting new tick-associated viruses: what comes next?. Future Virol. 2020; 15(1): doi:10.2217/fvl-2019-0149


36- Okar SV, Bekircan-Kurt CE, Hacıoğlu S, Erdem-Özdamar S, Özkul A, Ergünay K. Toscana virus associated with Guillain-Barré syndrome: a case-control study. Acta Neurol Belg. 2020; doi: 10.1007/s13760-020-01279-5.


37- Altay-Kocak A, Bozdayi G, Michel J, Polat M, Kanik-Yuksek S, Tezer H, Ozkul A, Ahmed K, Nitsche A, Ergunay K. Multi-assay investigation of viral etiology in pediatric central nervous system infections. J Infect Dev Ctries. 2020;14(6):572-579.


38- Kuhn JH, Adkins S, Alioto D, Alkhovsky SV, Amarasinghe GK, Anthony SJ, Avšič-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bartonička T, Basler C, Bavari S, Beer M, Bente DA, Bergeron É, Bird BH, Blair C, Blasdell KR, Bradfute SB, Breyta R, Briese T, Brown PA, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Buzkan N, Calisher CH, Cao M, Casas I, Chamberlain J, Chandran K, Charrel RN, Chen B, Chiumenti M, Choi IR, Clegg JCS, Crozier I, da Graça JV, Dal Bó E, Dávila AMR, de la Torre JC, de Lamballerie X, de Swart RL, Di Bello PL, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolja VV, Dolnik O, Drebot MA, Drexler JF, Dürrwald R, Dufkova L, Dundon WG, Duprex WP, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K,et al. 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2020; 165(12):3023-3072. doi: 10.1007/s00705-020-04731-2.


39- Ergünay K, Dinçer E, Kar S, Emanet N, Yalçınkaya D, Polat Dinçer PF, Brinkmann A, Hacıoğlu S, Nitsche A, Özkul A, Linton YM. Multiple orthonairoviruses including Crimean-Congo hemorrhagic fever virus, Tamdy virus and the novel Meram virus in Anatolia. Ticks Tick Borne Dis. 2020; 11(5):101448.


40- Földes K, Aligholipour Farzani T, Ergünay K, Ozkul A. Differential Growth Characteristics of Crimean-Congo Hemorrhagic Fever Virus in Kidney Cells of Human and Bovine Origin. Viruses. 2020 Jun 25;12(6). doi: 10.3390/v12060685.


41- Eyupoglu ND, Ergunay K, Acikgoz A, Akyon Y, Yilmaz E, Yildiz BO. Gut Microbiota and Oral Contraceptive Use in Overweight and Obese Patients with Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2020;105(12). doi: 10.1210/clinem/dgaa600.


42- Örsten S, Demirci-Duarte S, Ünalan-Altıntop T, Çakar A, Sancak B, Ergünay K, Özkuyumcu C. Low prevalence of hypervirulent Klebsiella pneumoniae in Anatolia, screened via phenotypic and genotypic testing. Acta Microbiol Immunol Hung. 2020;. doi: 10.1556/030.2020.01143.


43- Garrison AR, Alkhovsky Альховский Сергей Владимирович SV, Avšič-Županc T, Bente DA, Bergeron É, Burt F, Di Paola N, Ergünay K, Hewson R, Kuhn JH, Mirazimi A, Papa A, Sall AA, Spengler JR, Palacios G, Consortium IR. ICTV Virus Taxonomy Profile: Nairoviridae. J Gen Virol. 2020; 101(8):798-799.


44- Hanifehnezhad A, Kehribar EŞ, Öztop S, Sheraz A, Kasırga S, Ergünay K, Önder S, Yılmaz E, Engin D, Oğuzoğlu TÇ, Şeker UÖŞ, Yılmaz E, Özkul A. Characterization of local SARS-CoV-2 isolates and pathogenicity in IFNAR-/- mice. Heliyon. 2020; 6(9):e05116. doi: 10.1016/j.heliyon.2020.e05116.


45- Ergünay K, Polat C, Özkul A. Vector-borne viruses in Turkey: A systematic review and bibliography. Antiviral Res. 2020; 183:104934. doi: 10.1016/j.antiviral.2020.104934

.
46- Polat C, Ergin Ç, Akkaya Y, Oktem IMA. Investigation of Orthohantavirus seroprevalence in northern rural areas of Denizli province, Turkey. Jpn J Infect Dis 2020; 73(3): 201-204.

 

47- Unalan-Altintop, T., Vahabov, C., Ergunay, K., Kurt, O., Kav, T., Akyon, Y., Erguven, S Investigation of Dientamoeba fragilis and Blastocystis in patients from Turkey with ulcerative colitis and irritable bowel syndrome: Any relation with genotypes? Acta Tropica, 2022; 231, art. no. 106451.

 

48- Kamau J, Ergunay K, Webala PW, Justi SA, Bourke BP, Kamau MW, Hassell J, Chege MN, Mwaura DK, Simiyu C, Kibiwot S, Onyuok S, Caicedo-Quiroga L, Li T, Zimmerman DM, Linton YM. A Novel Coronavirus and a Broad Range of Viruses in Kenyan Cave Bats. Viruses. 2022 Dec 17;14(12):2820.

 

49- Kuhn JH, Adkins S, Alkhovsky SV, Avšič-Županc T, Ayllón MA, Bahl J, Balkema- Buschmann A, Ballinger MJ, Bandte M, Beer M, Bejerman N, Bergeron É, Biedenkopf N, Bigarré L, Blair CD, Blasdell KR, Bradfute SB, Briese T, Brown PA, Bruggmann R, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Candresse T, Carson J, Casas I, Chandran K, Charrel RN, Chiaki Y, Crane A, Crane M, Dacheux L, Bó ED, de la Torre JC, de Lamballerie X, de Souza WM, de Swart RL, Dheilly NM, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Drexler JF, Duprex WP, Dürrwald R, Easton AJ, Elbeaino T, Ergünay K, et al. 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2022 Dec;167(12):2857-2906.

 

50- Balaban HY, Aslan AT, Akdoğan-Kittana FN, Alp A, Dağ O, Ayar ŞN, Vahabov C, Şimşek C, Yıldırım T, Göker H, Ergünay K, Erdem Y, Büyükaşık Y, Şimşek H. Hepatitis E Virus Prevalence and Associated Risk Factors in High-Risk Groups: A Cross-Sectional Study. Turk J Gastroenterol. 2022 Jul;33(7):615-624.

 

51- Ergunay K, Mutinda M, Bourke B, Justi SA, Caicedo-Quiroga L, Kamau J, Mutura S, Akunda IK, Cook E, Gakuya F, Omondi P, Murray S, Zimmerman D, Linton YM. Metagenomic Investigation of Ticks From Kenyan Wildlife Reveals Diverse Microbial Pathogens and New Country Pathogen Records. Front Microbiol. 2022 Jul 1;13:932224.

 

52- Ahan RE, Hanifehnezhad A, Kehribar EŞ, Oguzoglu TC, Földes K, Özçelik CE, Filazi N, Öztop S, Palaz F, Önder S, Bozkurt EU, Ergünay K, Özkul A, Şeker UÖŞ. A Highly Potent SARS-CoV-2 Blocking Lectin Protein. ACS Infect Dis. 2022 Jul 8;8(7):1253-1264.

 

53- Papa A, Marklewitz M, Paraskevopoulou S, Garrison AR, Alkhovsky SV, Avšič- Županc T, Bente DA, Bergeron É, Burt F, Di Paola N, Ergünay K, Hewson R, Mirazimi A, et al. History and classification of Aigai virus (formerly Crimean-Congo haemorrhagic fever virus genotype VI). J Gen Virol. 2022 Apr;103(4):001734.

 

54- Dinçer E, Timurkan MÖ, Oğuz B, Şahindokuyucu İ, Şahan A, Ekinci M, Polat C, Ergünay K. Several Tick-Borne Pathogenic Viruses in Circulation in Anatolia, Turkey. Vector Borne Zoonotic Dis. 2022 Feb;22(2):148-158.

 

55- Gökahmetoğlu S, Polat C, Atalay MA, Sezgin GC, Ergör G, Aygen B, Gürsoy Ş, Abacıoğlu YH. Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turk J Gastroenterol 2022. doi: 10.5152/tjg.2022.21822.

 

56- Ergunay K, Dincer E, Justi SA, Bourke BP, Nelson SP, Liao HM, Timurkan MO, Oguz B, Sahindokuyucu I, Gokcecik OF, Reinbold-Wasson DD, Jiang L, Achee NL, Grieco JP, Linton YM. Impact of nanopore-based metagenome sequencing on tick- borne virus detection. Front Microbiol. 2023 May 30;14:1177651.