PAXIS Lab Research Group

About Research Infrastructure Researchers Ongoing Projects Completed Projects Publications

About

Research Infrastructure

• Oven (Static/Shaking)
• Precision Balance
• Ph Meter
• Thermoshaker
• Precision Balance
• Hot Water Bath
• Refrigerator
• Vortex
• Centrifuge
• Homogenizer
• Sonicator
• Muffle Furnace

Researchers

Assoc. Prof. Dr. Gözde KOŞARSOY AĞÇELİ
Sıla HOŞOĞLU (Master's Degree)
Lara AKAY (Undergraduate)
Eftalya İnci BALIKÇI (Undergraduate)

Ongoing Projects

• Effect of green synthesis nanoparticles on levan production from thermophilic microorganisms: Characterization and bioactivity (HACETTEPE UNIVERSITY SCIENTIFIC RESEARCH PROJECTS COORDINATION UNIT, Ongoing.)
• Determination of Drought Resistance Level with Photochemical and Antioxidant Defense Responses by Fullerenol and Green Synthesis Iron Nanoparticle Application in Aspir Carthamus tinctorius L Plant (HACETTEPE UNIVERSITY SCIENTIFIC RESEARCH PROJECTS COORDINATION UNIT, Ongoing.)

Completed Projects

• ZnO Produced by Microbial Methods Development of Polymer Nanocomposite Material from Nanoparticles and Curdlan Biopolymer
• Production of levan from microorganisms immobilized on Fe3O4 nanoparticles in molasses medium and determination of bioactivity of produced levan
• Microbial Synthesis, Characterization and Determination of Biocompatibility of Quantum Dots by In Vitro Studies
• Development of Biopolymeric Hydrogel Carrier System Obtained by Microbial Method, Characterization and Investigation of In Vitro and In Vitro Studies
• Determination of Antimicrobial Activity of Microbial Biopolymer Based Films Enriched with Different Essential Oils
• Determination of bioactivity of nanoparticles synthesized by biological means
• Investigation of microbial biopolymer production and use as antimicrobial surface
• Investigation of structural changes and bioactivity of new design polymer-metal based materials with physicochemical properties investigation

Publications

1. Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P., Jasrotia, R., Chauhan, P. K., & Ighalo, J. O. (2022). Multifunctional CuO nanoparticles with enhanced photocatalytic dye degradation and antibacterial activity. Sustainable Environmental Research, 32, 1-15.
2. Koşarsoy Ağçeli, G., & Günan Yücel, H. (2023). Levan production by Paenibacillus polymyxa immobilized on Fe3O4@ SiO2 nanoparticles using molasses medium with emphasis on the bioactivity. Journal of Polymers and the Environment, 31(12), 5355-5370.
3. Ağçeli, G. K. (2023). Similarities and differences of nano-sized levan synthesized by Bacillus haynesii at low and high temperatures: Characterization and bioactivity. International Journal of Biological Macromolecules, 253, 126804
4. Ağçeli, G. K., Hammamchi, H., Cihangir, N., & Aksu, Z. (2023). Biosynthesis of Zirconium dioxide nanoparticles by Streptomyces sp. HC1: Characterization and Bioactivity. Erzincan University Journal of Science and Technology, 16(1), 224-238.
5. Aracagök, Y. D., Ağçeli, G. K., & Kabalak, M. (2022). A New Approach for Dye Removal with a Polymer: Removal of Acid Orange 12 from Aqueous Solution with Shrimp Chitin. Commagene Journal of Biology, 6(2), 172-177
6. Dulta, K., Khongthaw, B., Singh, S., Thakur, A., Agçeli, G. K., & Thakur, K. (2023). Stropharia rugosoannulata Farlow ex Murrill (Wine Cap Stropharia or Garden Giant).
7. Ağçeli, G. K. (2024). Polymer and its nanocomposites as an antimicrobial coating for medical devices and implants. In Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants (pp. 161-180). Woodhead Publishing.
8. Dulta, K., Agçeli, G. K., Tangariya, P., Awasthi, Y. K., Sharma, R. B., Negi, T., ... & Negi, D. (2024). Potential of Nanotechnology for Improving Nutrient Efficiency of Temperate Horticulture Crops. In Novel Approach to Sustainable Temperate Horticulture (pp. 85-115). CRC Press.
9. Dulta, K., Kumar, K., Thakur, A., Singh, S., Agçeli, G. K., & Singh, D. (2024). 171Laetiporus sulphureus (Bull.) Murrill. In Edible and Medicinal Mushrooms of the Himalayas (pp. 171-187). CRC Press.
10. Ağçeli, G. K., Prakash, J., Dulta, K., & Chauhan, P. K. (2023). Silver-substituted nanoferrite-based composites for biomedical applications. In Magnetic Nanoferrites and their Composites (pp. 193-205). Woodhead Publishing.
11. A Novel Approach to Synthesize TiO2 Nanoparticles: Biosynthesis by Using Streptomyces sp. HC1, Ağçeli G., Hammachi H., Kodal S. P., Cihangir N., Aksu Z. Journal of Inorganic and Organometallic Polymers and Materials, 2020.
12. A Novel Approach of Synthesis Zinc Oxide Nanoparticles by Bergenia ciliata Rhizome Extract: Antibacterial and Anticancer Potential, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P. et al., J Inorg Organomet Polym, 2020.
13. Ecofriendly Synthesis of Zinc Oxide Nanoparticles by Carica papaya Leaf Extract and Their Applications, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P et al., Journal of Cluster Science, 2020.
14. Biogenic Production and Characterization of CuO Nanoparticles by Carica papaya Leaves and Its Biocompatibility Applications, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P et al., J Inorg Organomet Polym, 2021.
15. Development of Alginate-Chitosan Based Coating Enriched with ZnO Nanoparticles for Increasing the Shelf Life of Orange Fruits (Citrus sinensis L.), Dulta, K., Koşarsoy Ağçeli, G., Thakur, A et al., Journal of Polymers and the Environment, 2022.
16. Novel levan/bentonite/essential oil films: characterization and antimicrobial activity, Koşarsoy Ağçeli, G., Hammamchi, H., Cihangir, N., J Food Sci Technol, 2021.
17. Nano-sized biopolymer levan:Its antimicrobial,anti-biofilm and anti effects, Koşarsoy Ağçeli G., Cihangir N., Carbohydrate Research, 2020.
18. Development of ostrich eggshell and nano-levan-based edible biopolymer composite films: characterization and bioactivity, Koşarsoy Ağçeli, G., Polymer Bulletin, 2022.
19.    Synthesis, characterization and antimicrobial performance of novel nanostructured biopolymer film based on levan/clay/LL-37 antimicrobial peptide, Koşarsoy Ağçeli, G., Cihangir, N., Biocatalysis and Agricultural Biotechnology, 23, January 2020, 101421, https://doi.org/10.1016/j.bcab.2019.101421
20.    Mucormycosis: A Double Threat to COVID-19 Patients, Dulta, K., Kumar, K., Koşarsoy Ağçeli, G. P.K. Chauhan, Vinod Kumar, Pharmacologyonline, 2021.
21.    Koşarsoy Ağçeli G., Dulta K., Chauhan P., Chauhan P.K., Pal K. (2021) Progress in Nanomaterial Self-Assembly for Bio-scaffolds: Exclusive Biomedical Applications. In: Pal K. (eds) Bio-manufactured Nanomaterials. Springer, Cham. https://doi.org/10.1007/978-3-030-67223-2_17
22.    Koşarsoy Ağçeli G., Dulta K., Chauhan P., Chauhan P.K., Biological Synthesis of Nanomaterials and Their Advantages, Nanomaterials in Bionanotechnology, Taylor and Francis, eBook Published 18 August 2021, https://doi.org/10.1201/9781003139744
23.    Orujalipoor Ilghar,Polat Kinyas,Huang Yeng Chih, İde Semra,SEN MURAT,JENG U SER,KOSARSOY AGÇELI GÖZDE,CIHANGIR NILÜFER (2019). Partially sulfonated styrene-(ethylene-butylene)-styrene copolymers: Nanostructures, bio and electro-active properties. Materials Chemistry and Physics, 225, 399-405.,

About

Research Infrastructure

• Oven (Static/Shaking) • Precision Balance • Ph Meter • Thermoshaker • Precision Balance • Hot Water Bath • Refrigerator • Vortex • Centrifuge • Homogenizer • Sonicator • Muffle Furnace

Researchers

Assoc. Prof. Dr. Gözde KOŞARSOY AĞÇELİ Sıla HOŞOĞLU (Master's Degree) Lara AKAY (Undergraduate) Eftalya İnci BALIKÇI (Undergraduate)

Ongoing Projects

• Effect of green synthesis nanoparticles on levan production from thermophilic microorganisms: Characterization and bioactivity (HACETTEPE UNIVERSITY SCIENTIFIC RESEARCH PROJECTS COORDINATION UNIT, Ongoing.) • Determination of Drought Resistance Level with Photochemical and Antioxidant Defense Responses by Fullerenol and Green Synthesis Iron Nanoparticle Application in Aspir Carthamus tinctorius L Plant (HACETTEPE UNIVERSITY SCIENTIFIC RESEARCH PROJECTS COORDINATION UNIT, Ongoing.)

Completed Projects

• ZnO Produced by Microbial Methods Development of Polymer Nanocomposite Material from Nanoparticles and Curdlan Biopolymer • Production of levan from microorganisms immobilized on Fe3O4 nanoparticles in molasses medium and determination of bioactivity of produced levan • Microbial Synthesis, Characterization and Determination of Biocompatibility of Quantum Dots by In Vitro Studies • Development of Biopolymeric Hydrogel Carrier System Obtained by Microbial Method, Characterization and Investigation of In Vitro and In Vitro Studies • Determination of Antimicrobial Activity of Microbial Biopolymer Based Films Enriched with Different Essential Oils • Determination of bioactivity of nanoparticles synthesized by biological means • Investigation of microbial biopolymer production and use as antimicrobial surface • Investigation of structural changes and bioactivity of new design polymer-metal based materials with physicochemical properties investigation

Publications

1. Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P., Jasrotia, R., Chauhan, P. K., & Ighalo, J. O. (2022). Multifunctional CuO nanoparticles with enhanced photocatalytic dye degradation and antibacterial activity. Sustainable Environmental Research, 32, 1-15. 2. Koşarsoy Ağçeli, G., & Günan Yücel, H. (2023). Levan production by Paenibacillus polymyxa immobilized on Fe3O4@ SiO2 nanoparticles using molasses medium with emphasis on the bioactivity. Journal of Polymers and the Environment, 31(12), 5355-5370. 3. Ağçeli, G. K. (2023). Similarities and differences of nano-sized levan synthesized by Bacillus haynesii at low and high temperatures: Characterization and bioactivity. International Journal of Biological Macromolecules, 253, 126804 4. Ağçeli, G. K., Hammamchi, H., Cihangir, N., & Aksu, Z. (2023). Biosynthesis of Zirconium dioxide nanoparticles by Streptomyces sp. HC1: Characterization and Bioactivity. Erzincan University Journal of Science and Technology, 16(1), 224-238. 5. Aracagök, Y. D., Ağçeli, G. K., & Kabalak, M. (2022). A New Approach for Dye Removal with a Polymer: Removal of Acid Orange 12 from Aqueous Solution with Shrimp Chitin. Commagene Journal of Biology, 6(2), 172-177 6. Dulta, K., Khongthaw, B., Singh, S., Thakur, A., Agçeli, G. K., & Thakur, K. (2023). Stropharia rugosoannulata Farlow ex Murrill (Wine Cap Stropharia or Garden Giant). 7. Ağçeli, G. K. (2024). Polymer and its nanocomposites as an antimicrobial coating for medical devices and implants. In Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants (pp. 161-180). Woodhead Publishing. 8. Dulta, K., Agçeli, G. K., Tangariya, P., Awasthi, Y. K., Sharma, R. B., Negi, T., ... & Negi, D. (2024). Potential of Nanotechnology for Improving Nutrient Efficiency of Temperate Horticulture Crops. In Novel Approach to Sustainable Temperate Horticulture (pp. 85-115). CRC Press. 9. Dulta, K., Kumar, K., Thakur, A., Singh, S., Agçeli, G. K., & Singh, D. (2024). 171Laetiporus sulphureus (Bull.) Murrill. In Edible and Medicinal Mushrooms of the Himalayas (pp. 171-187). CRC Press. 10. Ağçeli, G. K., Prakash, J., Dulta, K., & Chauhan, P. K. (2023). Silver-substituted nanoferrite-based composites for biomedical applications. In Magnetic Nanoferrites and their Composites (pp. 193-205). Woodhead Publishing. 11. A Novel Approach to Synthesize TiO2 Nanoparticles: Biosynthesis by Using Streptomyces sp. HC1, Ağçeli G., Hammachi H., Kodal S. P., Cihangir N., Aksu Z. Journal of Inorganic and Organometallic Polymers and Materials, 2020. 12. A Novel Approach of Synthesis Zinc Oxide Nanoparticles by Bergenia ciliata Rhizome Extract: Antibacterial and Anticancer Potential, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P. et al., J Inorg Organomet Polym, 2020. 13. Ecofriendly Synthesis of Zinc Oxide Nanoparticles by Carica papaya Leaf Extract and Their Applications, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P et al., Journal of Cluster Science, 2020. 14. Biogenic Production and Characterization of CuO Nanoparticles by Carica papaya Leaves and Its Biocompatibility Applications, Dulta, K., Koşarsoy Ağçeli, G., Chauhan, P et al., J Inorg Organomet Polym, 2021. 15. Development of Alginate-Chitosan Based Coating Enriched with ZnO Nanoparticles for Increasing the Shelf Life of Orange Fruits (Citrus sinensis L.), Dulta, K., Koşarsoy Ağçeli, G., Thakur, A et al., Journal of Polymers and the Environment, 2022. 16. Novel levan/bentonite/essential oil films: characterization and antimicrobial activity, Koşarsoy Ağçeli, G., Hammamchi, H., Cihangir, N., J Food Sci Technol, 2021. 17. Nano-sized biopolymer levan:Its antimicrobial,anti-biofilm and anti effects, Koşarsoy Ağçeli G., Cihangir N., Carbohydrate Research, 2020. 18. Development of ostrich eggshell and nano-levan-based edible biopolymer composite films: characterization and bioactivity, Koşarsoy Ağçeli, G., Polymer Bulletin, 2022. 19.    Synthesis, characterization and antimicrobial performance of novel nanostructured biopolymer film based on levan/clay/LL-37 antimicrobial peptide, Koşarsoy Ağçeli, G., Cihangir, N., Biocatalysis and Agricultural Biotechnology, 23, January 2020, 101421, https://doi.org/10.1016/j.bcab.2019.101421 20.    Mucormycosis: A Double Threat to COVID-19 Patients, Dulta, K., Kumar, K.,  Koşarsoy Ağçeli, G. P.K. Chauhan, Vinod Kumar, Pharmacologyonline, 2021. 21.    Koşarsoy Ağçeli G., Dulta K., Chauhan P., Chauhan P.K., Pal K. (2021) Progress in Nanomaterial Self-Assembly for Bio-scaffolds: Exclusive Biomedical Applications. In: Pal K. (eds) Bio-manufactured Nanomaterials. Springer, Cham. https://doi.org/10.1007/978-3-030-67223-2_17 22.    Koşarsoy Ağçeli G., Dulta K., Chauhan P., Chauhan P.K., Biological Synthesis of Nanomaterials and Their Advantages, Nanomaterials in Bionanotechnology, Taylor and Francis, eBook Published 18 August 2021, https://doi.org/10.1201/9781003139744 23.    Orujalipoor Ilghar,Polat Kinyas,Huang Yeng Chih, İde Semra,SEN MURAT,JENG U SER,KOSARSOY AGÇELI GÖZDE,CIHANGIR NILÜFER (2019). Partially sulfonated styrene-(ethylene-butylene)-styrene copolymers: Nanostructures, bio and electro-active properties. Materials Chemistry and Physics, 225, 399-405.,