Pediatric Cilia Videomicroscopic Examination Laboratory

About

Research Infrastructure

•   Sweat test device
•   Spirometer
•   Whole body plethysmography
•   CO diffusion capacity measurement
•   Lung cleaning index measurement
•   Cilia videomicroscope
•   Polyomnography beds and devices

Researchers

•    Prof Dr Nural Kiper
•    Prof D U Özçelik
•    Prof Dr D Doğru Ersöz
•    Prof Dr E Yalçın
•    Prof Dr N Emiarlioğlu
•    Dr Best Özsezen
•    Dr D Ademhan
•    Dr H Büyüknayır
•    Dr İ Güzelkaş
•    Dr B Sunman

Ongoing Projects

•   Examination of clinical and laboratory data in the diagnosis and follow-up of patients with primary ciliary dyskinesia
•   Evaluation of sleep breathing disorders in patients with primary ciliary dyskinesia

Completed Projects

• Evaluation of polysomnography findings in Down syndrome patients
•   Evaluation of polysomnography findings in patients followed up with the diagnosis of mucopolysaccharidosis
• Evaluation of polysomnography findings in patients followed up with the diagnosis of Prader willi syndrome
•   Thesis: Evaluation of polysomnography findings in children with neuromuscular diseases
•   Thesis: Evaluation of obstructive sleep apnea in children with hypothalamic obesity and exogenous obesity
• Evaluation of Cilia Structure and Functions by Cell Culture Method in Patients with Primary Ciliary Dyskinesia

Publications

•    Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU. Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children. Turk J Pediatr. 2019;61(1):20-25. doi: 10.24953/turkjped.2019.01.004. PMID: 31559717.
•    Emiralioğlu N, Karadağ B, Özçelik HU. Quality of Life Questionnaire for Turkish Patients with Primary Ciliary Dyskinesia. Turk Thorac J. 2017 Jan;18(1):19-22. doi: 10.5152/TurkThoracJ.2017.16049. Epub 2017 Jan 1. PMID: 29404153; PMCID: PMC5783167.
•    Emiralioğlu N, Özçelik U, Yalçın E, Doğru D, Kiper N. Diagnosis of cystic fibrosis with chloride meter (Sherwood M926S chloride analyzer®) and sweat test analysis system (CFΔ collection system®) compared to the Gibson Cooke method. Turk J Pediatr. 2016;58(1):27-33. doi: 10.24953/turkjped.2016.01.004. PMID: 27922233.

•    Dogru D, Çakır E, Şişmanlar T, Çobanoğlu N, Pekcan S, Cinel G, Yalçın E, Kiper N, Şen V, S Şen H, Ercan Ö, Keskin Ö, B Eltan S, Al Shadfan LM, Yazan H, Altıntaş DU, Şaşihüseyinoğlu Ş, Sapan N, Çekiç Ş, Çokuğraş H, A Kılınç A, R Gürsoy T, Aslan AT, Bingöl A, Başaran AE, Özdemir A, Köse M, Hangül M, Emiralioğlu N, Tuğcu G, Yüksel H, Yılmaz Ö, Orhan F, Gayretli Aydın ZG, Topal E, Tamay Z, Süleyman A, Can D, Bal CM, Çaltepe G, Özçelik U. Cystic fibrosis in Turkey: First data from the national registry. Pediatr Pulmonol. 2020 Feb;55(2):541-548. doi: 10.1002/ppul.24561. Epub 2019 Nov 11. PMID: 31710166.
•    Emiralioğlu N, Taşkıran EZ, Koşukcu C, Bilgiç E, Atilla P, Kaya B, Günaydın Ö, Yüzbaşıoğlu A, Tuğcu GD, Ademhan D, Eryılmaz Polat S, Gharibzadeh Hızal M, Yalçın E, Doğru D, Kiper N, Alikaşifoğlu M, Özçelik U. Genotype and phenotype evaluation of patients with primary ciliary dyskinesia: First results from Turkey. Pediatr Pulmonol. 2020 Feb;55(2):383-393. doi: 10.1002/ppul.24583. Epub 2019 Nov 25. PMID: 31765523.
•    Zengin Akkus P, Gharibzadeh Hizal M, Ilter Bahadur E, Ozmert EN, Eryilmaz Polat S, Ozdemir G, Karahan S, Yalcin E, Dogru Ersoz D, Kiper N, Ozcelik U. Developmental and behavioral problems in preschool-aged primary ciliary dyskinesia patients. Eur J Pediatr. 2019 Jul;178(7):995-1003. doi: 10.1007/s00431-019-03382-z. Epub 2019 Apr 27. PMID: 31030258.
•    Halbeisen FS, Shoemark A, Barbato A, Boon M, Carr S, Crowley S, Hirst R, Karadag B, Koerner-Rettberg C, Loebinger MR, Lucas JS, Maitre B, Mazurek H, Özçelik U, Martinů V, Schwerk N, Thouvenin G, Tschanz SA, Yiallouros P, Goutaki M, Kuehni CE. Time trends in diagnostic testing for primary ciliary dyskinesia in Europe. Eur Respir J. 2019 Oct 24;54(4):1900528. doi: 10.1183/13993003.00528-2019. PMID: 31273043.
•    Lucas JS, Gahleitner F, Amorim A, Boon M, Brown P, Constant C, Cook S, Crowley S, Destouches DMS, Eber E, Mussaffi H, Haarman E, Harris A, Koerner-Rettberg C, Kuehni CE, Latzin P, Loebinger MR, Lorent N, Maitre B, Moreno-Galdó A, Nielsen KG, Özçelik U, Philipsen LKD, Pohunek P, Polverino E, Rademacher J, Robinson P, Snijders D, Yiallouros P, Carr SB. Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials. ERJ Open Res. 2019 Feb 1;5(1):00147-2018. doi: 10.1183/23120541.00147-2018. PMID: 30723730; PMCID: PMC6355979.
•    Iyigun I, Alikasifoglu A, Gonc N, Ozon A, Eryilmaz Polat S, Hizal M, Kiper N, Ozcelik U. Obstructive sleep apnea in children with hypothalamic obesity: Evaluation of possible related factors. Pediatr Pulmonol. 2020 Dec;55(12):3532-3540. doi: 10.1002/ppul.25097. Epub 2020 Oct 6. PMID: 32986303.
•    Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU. Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children. Turk J Pediatr. 2019;61(1):20-25. doi: 10.24953/turkjped.2019.01.004. PMID: 31559717.
•    Emiralioğlu N, Karadağ B, Özçelik HU. Quality of Life Questionnaire for Turkish Patients with Primary Ciliary Dyskinesia. Turk Thorac J. 2017 Jan;18(1):19-22. doi: 10.5152/TurkThoracJ.2017.16049. Epub 2017 Jan 1. PMID: 29404153; PMCID: PMC5783167.

Links

About

Research Infrastructure

•   Sweat test device
•   Spirometer
•   Whole body plethysmography
•   CO diffusion capacity measurement
•   Lung cleaning index measurement
•   Cilia videomicroscope
•   Polyomnography beds and devices

Researchers

•    Prof Dr Nural Kiper
•    Prof D U Özçelik
•    Prof Dr D Doğru Ersöz
•    Prof Dr E Yalçın
•    Prof Dr N Emiarlioğlu
•    Dr Best Özsezen
•    Dr D Ademhan
•    Dr H Büyüknayır
•    Dr İ Güzelkaş
•    Dr B Sunman

Ongoing Projects

•   Examination of clinical and laboratory data in the diagnosis and follow-up of patients with primary ciliary dyskinesia
•   Evaluation of sleep breathing disorders in patients with primary ciliary dyskinesia

Completed Projects

• Evaluation of polysomnography findings in Down syndrome patients
•   Evaluation of polysomnography findings in patients followed up with the diagnosis of mucopolysaccharidosis
• Evaluation of polysomnography findings in patients followed up with the diagnosis of Prader willi syndrome
•   Thesis: Evaluation of polysomnography findings in children with neuromuscular diseases
•   Thesis: Evaluation of obstructive sleep apnea in children with hypothalamic obesity and exogenous obesity
• Evaluation of Cilia Structure and Functions by Cell Culture Method in Patients with Primary Ciliary Dyskinesia

Publications

•    Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU. Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children. Turk J Pediatr. 2019;61(1):20-25. doi: 10.24953/turkjped.2019.01.004. PMID: 31559717.
•    Emiralioğlu N, Karadağ B, Özçelik HU. Quality of Life Questionnaire for Turkish Patients with Primary Ciliary Dyskinesia. Turk Thorac J. 2017 Jan;18(1):19-22. doi: 10.5152/TurkThoracJ.2017.16049. Epub 2017 Jan 1. PMID: 29404153; PMCID: PMC5783167.
•    Emiralioğlu N, Özçelik U, Yalçın E, Doğru D, Kiper N. Diagnosis of cystic fibrosis with chloride meter (Sherwood M926S chloride analyzer®) and sweat test analysis system (CFΔ collection system®) compared to the Gibson Cooke method. Turk J Pediatr. 2016;58(1):27-33. doi: 10.24953/turkjped.2016.01.004. PMID: 27922233.

•    Dogru D, Çakır E, Şişmanlar T, Çobanoğlu N, Pekcan S, Cinel G, Yalçın E, Kiper N, Şen V, S Şen H, Ercan Ö, Keskin Ö, B Eltan S, Al Shadfan LM, Yazan H, Altıntaş DU, Şaşihüseyinoğlu Ş, Sapan N, Çekiç Ş, Çokuğraş H, A Kılınç A, R Gürsoy T, Aslan AT, Bingöl A, Başaran AE, Özdemir A, Köse M, Hangül M, Emiralioğlu N, Tuğcu G, Yüksel H, Yılmaz Ö, Orhan F, Gayretli Aydın ZG, Topal E, Tamay Z, Süleyman A, Can D, Bal CM, Çaltepe G, Özçelik U. Cystic fibrosis in Turkey: First data from the national registry. Pediatr Pulmonol. 2020 Feb;55(2):541-548. doi: 10.1002/ppul.24561. Epub 2019 Nov 11. PMID: 31710166.
•    Emiralioğlu N, Taşkıran EZ, Koşukcu C, Bilgiç E, Atilla P, Kaya B, Günaydın Ö, Yüzbaşıoğlu A, Tuğcu GD, Ademhan D, Eryılmaz Polat S, Gharibzadeh Hızal M, Yalçın E, Doğru D, Kiper N, Alikaşifoğlu M, Özçelik U. Genotype and phenotype evaluation of patients with primary ciliary dyskinesia: First results from Turkey. Pediatr Pulmonol. 2020 Feb;55(2):383-393. doi: 10.1002/ppul.24583. Epub 2019 Nov 25. PMID: 31765523.
•    Zengin Akkus P, Gharibzadeh Hizal M, Ilter Bahadur E, Ozmert EN, Eryilmaz Polat S, Ozdemir G, Karahan S, Yalcin E, Dogru Ersoz D, Kiper N, Ozcelik U. Developmental and behavioral problems in preschool-aged primary ciliary dyskinesia patients. Eur J Pediatr. 2019 Jul;178(7):995-1003. doi: 10.1007/s00431-019-03382-z. Epub 2019 Apr 27. PMID: 31030258.
•    Halbeisen FS, Shoemark A, Barbato A, Boon M, Carr S, Crowley S, Hirst R, Karadag B, Koerner-Rettberg C, Loebinger MR, Lucas JS, Maitre B, Mazurek H, Özçelik U, Martinů V, Schwerk N, Thouvenin G, Tschanz SA, Yiallouros P, Goutaki M, Kuehni CE. Time trends in diagnostic testing for primary ciliary dyskinesia in Europe. Eur Respir J. 2019 Oct 24;54(4):1900528. doi: 10.1183/13993003.00528-2019. PMID: 31273043.
•    Lucas JS, Gahleitner F, Amorim A, Boon M, Brown P, Constant C, Cook S, Crowley S, Destouches DMS, Eber E, Mussaffi H, Haarman E, Harris A, Koerner-Rettberg C, Kuehni CE, Latzin P, Loebinger MR, Lorent N, Maitre B, Moreno-Galdó A, Nielsen KG, Özçelik U, Philipsen LKD, Pohunek P, Polverino E, Rademacher J, Robinson P, Snijders D, Yiallouros P, Carr SB. Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials. ERJ Open Res. 2019 Feb 1;5(1):00147-2018. doi: 10.1183/23120541.00147-2018. PMID: 30723730; PMCID: PMC6355979.
•    Iyigun I, Alikasifoglu A, Gonc N, Ozon A, Eryilmaz Polat S, Hizal M, Kiper N, Ozcelik U. Obstructive sleep apnea in children with hypothalamic obesity: Evaluation of possible related factors. Pediatr Pulmonol. 2020 Dec;55(12):3532-3540. doi: 10.1002/ppul.25097. Epub 2020 Oct 6. PMID: 32986303.
•    Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU. Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children. Turk J Pediatr. 2019;61(1):20-25. doi: 10.24953/turkjped.2019.01.004. PMID: 31559717.
•    Emiralioğlu N, Karadağ B, Özçelik HU. Quality of Life Questionnaire for Turkish Patients with Primary Ciliary Dyskinesia. Turk Thorac J. 2017 Jan;18(1):19-22. doi: 10.5152/TurkThoracJ.2017.16049. Epub 2017 Jan 1. PMID: 29404153; PMCID: PMC5783167.

Links