• Luminex
• Flow Cytometry
• Iseq
• Nextseq
• Ez1
• ABI 3100
• Elisa Reader
• Washer
• Thermal Cycler/-20
• Dr. Öğr. Üyesi Çağman Tan
• Dr. Öğr. Gör Sevil Oskay Halaçlı
• Arş. Gör. Dr. Hacer Neslihan Bildik
• Arş. Gör Begüm Özbek
• Arş. Gör İsmail Yaz
• 1003 Tübitak “Investigation of innate immunity defects, combined immunodeficiencies and primary immunodeficiencies with immune dysregulation by genetic and advanced immunological methods” Start: 01.08.2018 End: 01.02.2021
• Project Code: TOA-2020- 18791 Project Type: Priority A. Start Date: 14.05.2020 End Date: 16.05.2022 Duration: 24(month) Title: Hacettepe University Faculty of Medicine Hospital Internal Diseases wards of the new Corona virus Investigation of the immunological characteristics and genetic predispositions of patients hospitalized with COVID19.
• Project Code: TKB -2020-18135 Project Type: Career B. Start Date: 20.05.2020 End Date: 20.02.2021 Duration: 9(month) Title: STIM1 GENERAL FUNCTIONAL STUDY Project Code: TSA-2020-18443 Project Type : K. Research Start Date: 19.03.2020 End Date: 19.09.2022 Duration: 24(months) Title: Systemic Secukinumab Treatment in Ankylosing Spondylitis Patients The Relationship between Systemic and Tear Proinflammatory Cytokines and Ocular Surface Findings
• TSA-2019-17812 Project Type: K. Research Start Date: 11.06.2019 End Date: 11.06.2020 Status: Ongoing Duration: 6 (months) Title: Endometrial microbiata results of unexplained infertility patients and fertile patients Comparison of dometrial microbiata results with 16srRNA misequencing method
• Project Code: TYL-2019-17774 Project Type: M.Sc. Start Date: 13.05.2019 End Date: 13.05.2021 Working Period: 18(months) Title: LRBA in Adult Patients with Inflammatory Bowel Disease and Celiac Disease Diagnoses Investigation of Primary Immunodeficiency Associated with LPS Responsive Beige Like Anchor Deficiency
• Project Code: TSA-2019-17759 Project Type: K. Research Head. Date: 27.06.2019 End Date: 27.12.2021 Ending Period: 24(months) Title: Early Onset Inflammation Investigation of Children with Chronic Diarrhea Similar to Inflammatory Bowel Disease and Inflammatory Bowel Disease in Terms of Responsible Genes
• Project Code: TSA-2019-17276 Project Type: K. Research Start Date: 19.02.2019 End Date: 19.02.2021 Status: Walking Time: 18(months) Title: In Children with Familial Mediterranean Fever or Systemic Juvenile Idiopathic Arthritis Disease Evaluation of Cytokine Response with Dental and Periodontal Condition
• Project Code: THD-2017-15876 Project Type: Rapid Support Start Date: 28.11.2017 End Date: 15.10.2018 Position: Executive Status: Closed Period: 9(months) Title: HLA Allelic Polymorphism in Turkish Children with Kawasaki Disease Investigating
• Project Code: THD-2017-14742 Project Type: Rapid Support Start Date: 05.10.2017 End Date: 15.08.2019 Position: Researcher Status: Closed Period: 18(months) Title: IRF7 gene mutation in individuals with severe influenza virus infection investigating the existence
• Project Code: TSA-2017-15486 Project Type: K. Research Start Date: 10.11.2017 End Date: 21.04.2020 Position: Researcher Status: Closed Period: 24(months) Title: Target Gene by Next Generation Sequencing Method Detection of Gene Mutations Associated with Subacute Sclerosing Panencephalitis (SSPE) Disease Project Code: TSA-2017-15449
• Project Type: K. Research Start Date: 17.11.2017 End Date: 04.02.2019 Position: Researcher Status: Closing Time: 14(months) Title: Tear proin inflammatory and anti-inflammatory cytokine levels and growth factor concentrations in unilateral pterygium cases. investigating the change
• Project Code: TSA-2017-14152 Project Type: K. Research Start Date: 14.06.2017 End Date: 18.06.2019 Position: Researcher Status: Closing Period: 24(months) Title: Patients with bronchial ectasis other than cystic fibrosis in childhood Investigation of the relationship between vascular binding lectin gene polymorphism and clinical and laboratory findings of the disease.
• Project Code: THD-2017-13454 Project Type: Rapid Support Start Date: 23.03.2017 End Date: 02.04.2019 Position: Researcher Status: Closing Period: 18(months) Title: Periodontal status and clinic in patients with cystic fibrosis Evaluation of immunological microbiological data
• Project Code: THD-2017-13548 Project Type: Rapid Support Start Date: 20.02.2017 End Date: 22.12.2017 Position: Researcher Status: Closing Period: 6(months) Title: Tumor necrosis factor 308 GA and Investigation of terleukin 1 511 CT polymorphisms Project Code: THD-2017-13157
• Project Type: Quick Support Chief. Date: 24.03.2017 End Date: 26.03.2018 Position: Researcher Status: Closing Period: 6(months) Title: Evaluation of Periodontal Status in Various Types of Immunodeficiency Conditions and Determination of the Gingival Crevice Fluid Cytokine Profile
• Project Code: TB B -2016-12785 Project Type: B. Success Start Date: 22.11.2016 End Date: 10.03.2017 Position: Executive Status: Closing Period: 3 (months) Title: FAS and Polymorphisms in CASP8 Genes May Contribute to the Development of ALPS Phenotype: 25 Patients Considered Likely ALPS
• Project Code: TED-2016-10394 Project Type: Event Participation Start Date: 28.04.2016 End Date: 11.11.2016 Position: Researcher Status: Closing Time: 3 (months) Title: Halitosis and Immunological Treatment of Plaque-Associated Gingivitis Examining the Effect on the Parameters
• Project Code: THD-2016-5336 Project Type: Rapid Support Start Date: 27.06.2016 End Date: 31.07.2017 Position: Executive Status: Closed Period: 12(months) Title: DETERMINATION OF MOROCCO GENE EXPRESSION IN PATIENTS WITH POSSIBLE ALPS DIAGNOSIS Project Code: TSA-2016-9087 Project Type: K. Research Start Date: 19.04.2016 End Date: 27.10.2017 Position: Executive Status: Closing Period: 18(months) Title: Next Generation Sequencing of Primary Antibody Deficiency Genetic Diseases Scanning by Method
• Adenosine Deaminase Type II Deficiency: Severe Chronic Neutropenia, Lymphoid Infiltration in Bone Marrow, and Inflammatory Features, M Süleyman, Ç Tan, A Uner, Ç İnkaya, S Aytaç, Y Büyükaşık, K Boztug, Immunological Investigations, 1-9 2020
• Evaluation of periodontal status and cytokine/chemokine profile of GCF in patients with severe congenital neutropenia B Acar, DÇ Ayvaz, Ç Tan, B Özbek, İ Yaz, YD Yıldırım, C Özşin-Özler, Odontology, 1-9 2020
• Recurrent Oral Aphtha, Diarrhea, Pneumonia, And Respiratory Distress Since Infancy: STAT1 GOF defect ES Aytekin, Ç Tan, DC Ayvaz, N Kiper, I Tezcan Authorea Preprints 2020
• Recurrent Demyelinating Episodes as Sole Manifestation of Inherited CD59 Deficiency I Solmaz, ES Aytekin, D Çağdaş, C Tan, I Tezcan, R Gocmen, G Haliloglu, Neuropediatrics 51 (03), 206-210 2020
• Frequency of HLA Class I and Class II Alleles in Patients with CVID from Turkey B Ozbek, C Tan, I Yaz, C Kosukcu, S Esenboga, PG Cetinkaya, D Cagdas, Immunological Investigations, 1-9 2020
• Autoinflammation in addition to combined immunodeficiency: SLC29A3 gene defect D Çağdaş, N Sürücü, Ç Tan, B Kayaoğlu, RK Özgül, YZ Akkaya-Ulum, Molecular Immunology 121, 28-37 2020
• Impact of mannose‐binding lectin 2 gene polymorphisms on disease severity in noncystic fibrosis bronchiectasis in children D Dogru, SE Polat, Ç Tan, İ Tezcan, SS Yalçın, E Utine, B Oğuz, İ Yaz, Pediatric Pulmonology 55 (5), 1190-1198 2020
• A rare form of congenital neutropenia: VPS45 deficiency B Karaatmaca, D Cagdas, Ç Tan, S Aytaç, B Özbek, A Üner, F Gümrük, Scandinavian Journal of Immunology 91 (5), e12871 2020
• Elevated Interleukin‐17A expression in amlodipine‐induced gingival overgrowth SS Sume, E Berker, Y Ilarslan, O Ozer Yucel, C Tan, S Goyushov, Journal of Periodontal Research 2020
• Levels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis O Duruel, E Berker, C Özşin-Özler, M Gharibzadeh-Hızal, Ö Gürpınar, Cytokine 127, 154987 2020
• Lymphocyte Subgroups and KREC Numbers in Common Variable Immunodeficiency: A Single Center Study I Yaz, B Ozbek, YY Ng, PG Cetinkaya, SO Halacli, C Tan, M Kasikci, Journal of Clinical Immunology, 1-9 2020
• Characteristics of patients with C1 esterase inhibitor deficiency: a single center study. ES Aytekin, D Cagdas, C Tan, I Tezcan European annals of allergy and clinical immunology 2020
• In case of recurrent wheezing and bronchiolitis: Think again, it may be a primary immunodeficiency B Ozbek, DC Ayvaz, S Esenboga, SO Halacli, ES Aytekin, I Yaz, C Tan, Hemoglobin (g/dL) 9, 10.9-15.0 2020
• A Spectrum of Clinical Findings from ALPS to CVID: Several Novel LRBA Defects D Cagdas, SO Halaçlı, Ç Tan, B Lo, PG Çetinkaya, S Esenboğa, Journal of clinical immunology 39 (7), 726-738 2019
• Unusual Presentation of Autoimmune Polyglandular Syndrome Type 1 (aps1) D Vuralli, C Tan, H Gulsen, Y Unsal, DC Ayvaz, H Demir, A Ozon, 58th Annual ESPE 92
• Effects of oral prophylaxis including tongue cleaning on halitosis and gingival inflammation in gingivitis patients—a randomized controlled clinical trial B Acar, E Berker, Ç Tan, YD İlarslan, M Tekçiçek, İ Tezcan Clinical Oral Investigations 23 (4), 1829-1836 2019
• Tumor necrosis factor α‐308 G/A and interleukin 1 β‐511 C/T gene polymorphisms in patients with scarring acne G Akoglu, C Tan, DC Ayvaz, I Tezcan Journal of Cosmetic Dermatology 18 (1), 395-400 2019
• ADA deficiency: evaluation of the clinical and laboratory features and the outcome D Cagdas, PG Cetinkaya, B Karaatmaca, S Esenboga, C Tan, T Yılmaz, Journal of clinical immunology 38 (4), 484-493 2018
• Tumor necrosis factor α-308 G/A and interleukin 1 ß-511 C/T gene polymorphisms in patients with scarring acne. G Akoglu, C Tan, DC Ayvaz, I Tezcan A| A 1 (2), 3
• Outcome of Patients with Severe Combined Immunodeficiency/Combined Immunodeficiency due to ADA Deficiency DC Ayvaz, PG Cetinkaya, B Karaatmaca, S Esenboga, C Tan 2018
• Clinical and genetic features of IL12R beta 1 deficiency: Single center experience of 18 patients C Tan, D Cagdas-Ayvaz, A Metin, O Keskin, İ Tezcan, O Sanal Turkish J Pediatrics 2016
• Polymorphisms in FAS and CASP8 genes may contribute to the development of ALPS phenotype: a study in 25 patients with probable ALPS C Tan, RK Özgül, D Cagdas-Ayvaz, I Tezcan, Ö Sanal The Turkish journal of pediatrics 57 (2), 141 2016