Pediatric Metabolism Research Laboratory

About

Research Infrastructure

•   DNA Sequence Analysis Device
•   Microarray Washing Station
•   Hybridization Furnace
•   Oxygen Controlled Incubator
•   Incubator with Carbon Dioxide
•   -20 Deep freezer
•   With Inverted Microscope Camera
•   Safety cabin Class 2
•  -150 Freezer
•   Imaging Device
•   Thermal Cycler 4 units
•   Real Time Thermal Cycler
•   Fluorescence Reader
•   Microcentrifuges 4 units

Researchers

•    Prof.Dr.R. Köksal Özgül
•    Prof. Dr. Ali Dursun
•    Dr. Öğr . Üyesi Didem Yücel Yılmaz
•    Dr. Öğr. Gör. Selda Ayhan
•    Postdoctoral Researcher Neşe Vardar Acar
•    Rukiye Karatepe (Consultant: Prof.Dr.R. Köksal Özgül )
•    Can Koşukcu (Consultant: Prof.Dr.R. Köksal Özgül )
•    Mümine Küçükdemir (Consultant: Prof.Dr.R. Köksal Özgül )
•    Hacer Esra Gürses Cila (Consultant: Prof.Dr.R. Köksal Özgül )
•    Eda Özaydın (Consultant: Prof.Dr.Ali Dursun )
•    Damla Aygün (Consultant Dr. Öğr . Üyesi Didem Yücel Yılmaz)

Ongoing Projects

•   TÜBİTAK-118S427 1001 - Research Investigation of Autophagy Mechanism in Newly Defined Metabolic/Neurometabolic Diseases 01/12/2018 - 01/12/2021
•    TÜBİTAK-118S047 1003 - Priority Areas, Development of a Bedside Diagnostic System for Early Diagnosis and Follow-up of Phenylketonuria Consultant 15/09/2018 - 15/09/2020
•    TÜBİTAK-117R057 1001 - Developing a Sample Model of Bone Marrow Niche in Research In Vitro Culture Medium Executive 01/07/2018 - 01/07/2021
•    TÜBİTAK, 120Z784, 1002- Modeling of UNC79 Candidate Gene Associated with Synaptopathy and NALCN Channel Components Associated with it in Drosophila melanogaster and Investigation of Their Effects on Synapse Function 01/12/2020—01/07/2021

Completed Projects

•    217S548 Sample Model Development of Bone Marrow Niche in TÜBİTAK In Vitro Culture Medium
• 118S427 TÜBİTAK Investigation of Autophagy Mechanism in Newly Defined Metabolic/Neurometabolic Diseases
• 115S304 TÜBİTAK Investigation of the Role of Exosomes on Respiratory Tract Epithelial Cells in Cystic Fibrosis
•   315S132 TÜBİTAK Investigation of Natural Immunity Defects, Combined Immunodeficiencies and Primary Immunodeficiencies Caused by Immune Dysregulation by Genetic and Advanced Immunological Methods
•    216S891 TÜBİTAK Characterization of Human Bone Marrow Hematopoietic Stem/Precursor Cells by Metabolic Analysis
•    213S025 TÜBİTAK Bronchial Hyperactivity (BHR) and Genotype – Phenotype Relationship in Asthma
•   213S006 Hematopoietic Niche Characterization in Human Bone Marrow with TÜBİTAK Metabolome and Transcriptome Profiling
•   013 D09 103 001-307 Human Bone Marrow Hematopoietic Niche Characterization by Metabolome Analysis
•   THD-2019-17639 Investigation of the Relationship between Mitochondrial Dysfunction and Oxidative Stress in Metabolic Diseases
•   THD-2018-16383 Evaluation of the Relationship Between Androgen Receptor CAG Repeat Polymorphism and Pubertal Gynecomastia
•    THD-2017-13786 Evaluation of Complement Factor I Gene Polymorphism Frequency in Age-Related Macular Degeneration in Turkish Population
•    THD-2016-12181 Obtaining Decellularized Extracellular Matrix From Mesenchymal Stem Cells

Publications

Links

About

Research Infrastructure

•   DNA Sequence Analysis Device
•   Microarray Washing Station
•   Hybridization Furnace
•   Oxygen Controlled Incubator
•   Incubator with Carbon Dioxide
•   -20 Deep freezer
•   With Inverted Microscope Camera
•   Safety cabin Class 2
•  -150 Freezer
•   Imaging Device
•   Thermal Cycler 4 units
•   Real Time Thermal Cycler
•   Fluorescence Reader
•   Microcentrifuges 4 units

Researchers

•    Prof.Dr.R. Köksal Özgül
•    Prof. Dr. Ali Dursun
•    Dr. Öğr . Üyesi Didem Yücel Yılmaz
•    Dr. Öğr. Gör. Selda Ayhan
•    Postdoctoral Researcher Neşe Vardar Acar
•    Rukiye Karatepe (Consultant: Prof.Dr.R. Köksal Özgül )
•    Can Koşukcu (Consultant: Prof.Dr.R. Köksal Özgül )
•    Mümine Küçükdemir (Consultant: Prof.Dr.R. Köksal Özgül )
•    Hacer Esra Gürses Cila (Consultant: Prof.Dr.R. Köksal Özgül )
•    Eda Özaydın (Consultant: Prof.Dr.Ali Dursun )
•    Damla Aygün (Consultant Dr. Öğr . Üyesi Didem Yücel Yılmaz)

Ongoing Projects

•   TÜBİTAK-118S427 1001 - Research Investigation of Autophagy Mechanism in Newly Defined Metabolic/Neurometabolic Diseases 01/12/2018 - 01/12/2021
•    TÜBİTAK-118S047 1003 - Priority Areas, Development of a Bedside Diagnostic System for Early Diagnosis and Follow-up of Phenylketonuria Consultant 15/09/2018 - 15/09/2020
•    TÜBİTAK-117R057 1001 - Developing a Sample Model of Bone Marrow Niche in Research In Vitro Culture Medium Executive 01/07/2018 - 01/07/2021
•    TÜBİTAK, 120Z784, 1002- Modeling of UNC79 Candidate Gene Associated with Synaptopathy and NALCN Channel Components Associated with it in Drosophila melanogaster and Investigation of Their Effects on Synapse Function 01/12/2020—01/07/2021

Completed Projects

•    217S548 Sample Model Development of Bone Marrow Niche in TÜBİTAK In Vitro Culture Medium
• 118S427 TÜBİTAK Investigation of Autophagy Mechanism in Newly Defined Metabolic/Neurometabolic Diseases
• 115S304 TÜBİTAK Investigation of the Role of Exosomes on Respiratory Tract Epithelial Cells in Cystic Fibrosis
•   315S132 TÜBİTAK Investigation of Natural Immunity Defects, Combined Immunodeficiencies and Primary Immunodeficiencies Caused by Immune Dysregulation by Genetic and Advanced Immunological Methods
•    216S891 TÜBİTAK Characterization of Human Bone Marrow Hematopoietic Stem/Precursor Cells by Metabolic Analysis
•    213S025 TÜBİTAK Bronchial Hyperactivity (BHR) and Genotype – Phenotype Relationship in Asthma
•   213S006 Hematopoietic Niche Characterization in Human Bone Marrow with TÜBİTAK Metabolome and Transcriptome Profiling
•   013 D09 103 001-307 Human Bone Marrow Hematopoietic Niche Characterization by Metabolome Analysis
•   THD-2019-17639 Investigation of the Relationship between Mitochondrial Dysfunction and Oxidative Stress in Metabolic Diseases
•   THD-2018-16383 Evaluation of the Relationship Between Androgen Receptor CAG Repeat Polymorphism and Pubertal Gynecomastia
•    THD-2017-13786 Evaluation of Complement Factor I Gene Polymorphism Frequency in Age-Related Macular Degeneration in Turkish Population
•    THD-2016-12181 Obtaining Decellularized Extracellular Matrix From Mesenchymal Stem Cells

Publications

Links