• DISSOLUTION DEVICE (SOTAKS)
• ETUV (DEDEOĞLU)
• ETUV (SALVIS)
• OVEN (VACUUM)
• ETUV (Memmert)
• Heated shaker (EPTENDORF)
• Ultrasonic Bath (Sonorex)
• Ultrasonic Bath (Advantage Lab)
• HPLC HP1200 (AGILENT SYSTEM)
• SHIMADZU HPLC (With Fluorescent Detector)
• HPLC HP1260 (AGILENT SYSTEM)
• HPLC HP1200 (AGILENT SYSTEM)
• High Pressure Homogenizer (Microfluidics)
• MIXER (ULTRATURAX T25)
• LYOPHILIZER
• pH METER (SARTORIUS)
• pH Meter (Hanna)
• ROTAVAPOR
• MIXER (HEIDOLPH RZR 2021)
• MIXER (HEIDOLPH RZR 2021)
• MIXER (SILVERSON)
• CENTRIFUGAL (Sigma)
• CENTRIFUGE (Hettich)
• CENTRIFUGE (Hettich)
• CENTRIFUGE (Labofuge 200)
• CENTRIFUGAL (OHAUS)
• SPRAY-DRYER (BUCHI 290)
• HORIZONTAL SHAKER WITH WATER BATH (MEMMERT)
• HORIZONTAL SHAKER WITH WATER BATH (MEMMERT)
• HORIZONTAL SHAKER WITH WATER BATH (MEMMERT)
• WATER BATH (ŞİMŞEK LABORTEKNIK)
• LIBRA (SHIMADZU)
• LIBRA (SHIMADZU)
• ULTRA PRECISION SCALE (METTLER)
• ULTRASONIC PROBE (BANDELIN)
• SPECTROPHOTOMETER SHIMADZU UV-1700
• POLARIZED LIGHT MICROSCOPE (LEICA)
• Multi-point mixer with heater THERMO
• ULTRA FILTRATION DEVICE
• HIGH PRESSURE HOMOGENIZER
• Multi-point heater mixer (IKA)
• Vortex IKA
• Vortex IKA
• Vortex IKA
• Mechanical mixer (Heidolph)
• Pump (Milipore)
• Multi-point heater mixer (Tarrey Pines)
• Mixer (Falc)
• Magnetic Stirrer (Heidolph)
• Magnetic Stirrer (Heidolph)
• Vorteks Nuvemix
• Deep Freezer (- 20 °C) (Beko)
• Refrigerator (+4/-20 °C) (Sanyo)
• Refrigerator (Arcelik)
• MIXER (ULTRATURAX T18)
• ELISA PLATE READER
• PURE WATER DEVICE (MILLIPORE)
• VISCOMETER (HELIPATH)
• VISCOMETER (CONI PLATE)
• VISCOMETER SPINDLE
• REOMETER BROOKFIELD
• SURFACE TENSION DEVICE (Attension)
• PARTICLE SIZE ANALYSIS DEVICE (MALVERN-MASTERSIZER 2000)
• 3D Printer (FDM Type)
• Filament Machine (3Deve Composer 450)
• PARTICLE SIZE ANALYSIS DEVICE (MALVERN-NANOSIZER)
• TEXTURE ANALYZER XT-PLUS
• A refrigerator
• COLONY COUNTER (SuperCount)
• CLEAN AIR LAMINAR FLOW
• ULTRATURAX T18 (IKA)
• SHIMADZU PRECISION SCALE
• Multi-Point Magnetic Stirrer (Variomag)
• Multi-Point Magnetic Stirrer (Variomag)
• Multi-point heater mixer IKA
• 3D Printer (FDM Type)
• CENTRIFUGE (Hettich EBA21)
• Rotator (IsoLab)
• Vortex
• COULTER MODEL N4SD
• MULTI-POINT MIXER (VARIOMAG)
• MULTI POINT MIXER (THERMO) – Entering Water
• ELECTRO SPINNING DEVICE
• ETUV SALIS
• COOLER WATER BATH (POLYSCIENCE)
• Rotavapor (Buchi R-300)
• Heated Magnetic Stirrer (IsoTex SH-4C)
• GILSON PERISTALTIC PUMP
• HPLC HP1100 (AGILENT SYSTEM)
• HPLC HP1200 (AGILENT SYSTEM)
• Andersen Cascade Impactor
• Multi-Stage Liquid Impinger
• HPLC (SHIMADZU)
• IKA heater mixer
• Temperature Controlled Cabin
• Heated Magnetic Stirrer
• Heated Magnetic Stirrer
• Immersion Cooler
• Fine Vortex
• Microscope (Leica)
• PERFUSION SAMPLER
• ROTAVAPOR (IKA RV10)
• ROTAVAPOR (IKA RV10)
• DEIONIZED WATER DEVICE (MILLIPORE)
• ULTRASONIC BATH (ADVANTAGE LAB)
• Ultra Precision Balance Shimadzu
• WATER BATH WITH SHAKER (MEMMERT)
• ETUV Dedeoğlu
• ELGA ULTRASAF WATER DEVICE (Type 1)
• ELGA ULTRASAF WATER DEVICE (Type 2)
• LYOPHILIATOR LABCONCO
• AUTOCLAVE (HMC Hirayama)
• AUTOCLAVE (HMC Hirayama)
• RETSCH Ball Mill
• Heated Mixer IKA
• pH Meter Hanna
• pH Meter Sartorius
• SHIMADZU HPLC (with DAD and Fluorescent Detector)
• Vortex IKA
• High Pressure Homogenizer
• (Microfluidics)
• Millipore Integral-5 Ultra Pure Water Device (Type 1, Type 2)
• Deep Freeze (- 20 °C)
• LIBRA (SHIMADZU)
• LIBRA (SHIMADZU)
• Cutometer SEM 575
• Mexameter MX18
• Skin-pH-meter PH900
• TewameterTM 210
• Prof. Dr. Levent Öner (Öğretim Üyesi)
• Prof.Dr. Sema Çalış (Öğretim Üyesi)
• Prof. Dr. Sevda Şenel (Öğretim Üyesi)
• Prof.Dr. Selma Şahin (Öğretim Üyesi)
• Prof. Dr. İmran Vural (Öğretim Üyesi)
• Prof. Dr. Betül Arıca Yegin (Öğretim Üyesi)
• Prof. Dr. Erem Bilensoy (Öğretim Üyesi)
• Prof. Dr. R. Neslihan Gürsoy (Öğretim Üyesi)
• Prof. Dr. Sibel Pehlivan (Öğretim Üyesi)
• Prof. Dr. Hakan Eroğlu (Öğretim Üyesi)
• Dr.Öğr.Ü. Kıvılcım Öztürk Atar (Öğretim Üyesi)
• Dr.Öğr.Ü. Nazlı Erdoğdu (Öğretim Üyesi)
• Dr.Öğr.Ü. Tuğba Gülsün İnal (Öğretim Üyesi)
• Dr.Öğr.Ü. Selin Seda Timur (Öğretim Üyesi)
• Dr.Öğr.Ü. Yağmur Akdağ Çaylı (Öğretim Üyesi)
• Öğr. Gör. Dr. Cem Varan (Öğretim Elemanı)
• Öğr. Gör. Dr. Tuğba Çopur (Öğretim Elemanı)
• Arş. Gör. Dr. Eren Aytekin (Öğretim Elemanı)
• Arş. Gör. Dr. Nihan İzat (Öğretim Elemanı)
• Arş. Gör. Selin Parmaksız (Öğretim Elemanı)
• Arş. Gör. Esra Pezik (Öğretim Elemanı)
• Arş. Gör. Nihat Kurt (Öğretim Elemanı)
• Ecz. Aslıhan Arslan (Tez Öğrencisi)
• Ecz. Beril Taş (Tez Öğrencisi)
• Ecz. Caner Eryol (Tez Öğrencisi)
• Ecz. Emine Vural (Tez Öğrencisi)
• Ecz. Fatma Betül Arslan (Tez Öğrencisi)
• Ecz.Meryem Kaplan (Tez Öğrencisi)
• Ecz. Ceren Kılınç (Tez Öğrencisi)
• Ecz. Ahmet Batuhan Dinç (Tez Öğrencisi)
• Ecz. Ece Türkmen (Tez Öğrencisi)
• Ecz. Neslihan Batur (Tez Öğrencisi)
• Ecz. Elif Erdoğan (Tez Öğrencisi)
• Ecz. Ertan Özdemir (Tez Öğrencisi)
• Ecz. (B.U.) Müge Geneş (Tez Öğrencisi)
• Ecz.Şemsi Muratoğlu (Tez Öğrencisi)
• Ecz.Fatma Kır (Tez Öğrencisi)
• Ecz. Meryem Kılınçarslan (Tez Öğrencisi)
• Ecz. Fatıma Al-Sulaıtı (Tez Öğrencisi)
• Ecz. Yakup Gültekin (Tez Öğrencisi)
• Ecz. Gözde Barın (Tez Öğrencisi)
• Ecz. Ayşe Gençer (Tez Öğrencisi)
• Ecz.Ceren Duraloğlu (Tez Öğrencisi)
• Ecz. Pelinsu Korucu (Tez Öğrencisi)
• Ecz. Gülsüm Kabol (Tez Öğrencisi)
• Ecz. Betül Gür (Tez Öğrencisi)
• Ecz. Şeydanur Gülsever (Tez Öğrencisi)
• Ecz. Safiye Akkın (Tez Öğrencisi)
• Ecz. Nurbanu Demirtürk (Tez Öğrencisi)
• Ecz. Ece Çobanoğlu (Tez Öğrencisi)
• Ecz. Gülzeynep Atak (Tez Öğrencisi)
• Ecz. Şuayp Ak (Tez Öğrencisi)
• Ecz. Sümeyra Pancur (Tez Öğrencisi)
• Ecz. Halise Betül Aslan (Tez Öğrencisi)
• Ecz. Yeliz Fidan (Tez Öğrencisi)
• Ecz. Fadime Dilara Aydın (Tez Öğrencisi)
• Ecz. Stela Muçaj (Tez Öğrencisi)
• Ecz. Büşra Teke (Tez Öğrencisi)
• Ecz. Melih Zeki Kaya (Tez Öğrencisi)
• Ecz. Feyza Nur Kadıoğlu (Tez Öğrencisi)
• Ecz. Damla Güngör (Tez Öğrencisi)
• Ecz. Gizem Tezel (Tez Öğrencisi)
• Ecz. Damla Güngör (Tez Öğrencisi)
• Ecz. Betül Topçu (Tez Öğrencisi)
• Ecz. Tuğba Sevinç Çevik (Tez Öğrencisi)
• Ecz. Serenay Ceylan (Tez Öğrencisi)
• Ecz. Keishid Abtahi (Tez Öğrencisi)
• Ecz. Gizem Zeytinoğlu (Tez Öğrencisi)
• Ecz. Ziyneti Eke (Tez Öğrencisi)
• Ecz. Elif Bahar Yurttaş (Tez Öğrencisi)
• Ecz. Büsra Dudu Öztürk (Tez Öğrencisi)
• Ecz. Bilgesu Kasurka (Tez Öğrencisi)
• Ecz. Zeynep Merve Geyik (Tez Öğrencisi)
• Optimization of Solubility and Dissolution Properties of Formulations Containing Celecoxib Using Artificial Neural Network Design, TÜBİTAK 120S229
• Active Targeting of Irinotecan and STAT3 Inhibitor Loaded PLGA-PEG Nanoparticles to Small Cell Lung Cancer and In Vivo-In Vitro Evaluation, TÜBİTAK 217S449
• Development of Nanocarrier System Containing Immunotherapeutic Targeted to the Tumor Microenvironment for the Treatment of Non-Small Cell Lung Cancer and Evaluation in Vitro/In Vivo, TÜBİTAK 119R055
• Development of New Generation Targeted Nanobiotherapeutics for Use in the Treatment of Macular Edema, TÜBİTAK 2016S700
• In vitro-in vivo evaluation of the efficacy and safety of immunochemotherapeutic nanoplexes in the treatment of colon cancer, TÜBİTAK 217S610
• Development of Actively Targeted, Multi-Drug-Loaded Nanoparticles to Overcome Drug Resistance in the Treatment of Non-Hodgkin Lymphoma and Evaluation of In Vitro-In Vivo Efficacy and Safety, TÜBİTAK 220S051
• Design, Optimization and Evaluation of Memantine Loaded Nanosystems for Neurodegenerative Diseases, TÜBİTAK 219S811
• Design and Characterization of a Customizable Drug Delivery System for the Treatment of Uterine Cancer with a Three-Dimensional (3D) Printer, TÜBİTAK 119S809
• Development of a porin-based anti-Salmonella multivalent vaccine formulation for non-invasive inmmunisation, BVNCP3-21
• Development of a combined drug containing bioadhesive carrier system to be used in the topical treatment of dermal infections in the veterinary field, THD-2020-18516
• Development of a vaccine against toxoplasmosis with a new adjuvant system containing recombinant protein antigens, TDK-2020-18606
• Investigation of the Effect of Rifampicin on Drug Disposition in the Liver and Pharmacokinetic Modeling, TSA-2019-17756
• Development of orodispersible tablet formulations containing rasagiline, in vitro and in vivo evaluation, TDK-2018-17258
• Preformulation Studies on a Newly Synthesized 1,4-Dihydropyridine Derived Substance with Solubility Problem Effective in the Treatment of Hypertension, THD-2019-18409
• Development, Characterization, and Evaluation of Treatment Efficacy in IPF Cell Culture Model of Nintedanib and miR29b-Loaded Lipoplex Formulations for Use in Idiopathic Pulmonary Fibrosis IPF Treatment, 18783
• Effect of Myosin Light Chain Kinase Inhibitor (ML-7) Loaded Nanofiber Polymers on Myometrium Contraction, TDK-2020-18569
• Imaging the effect of cyclodextrin nanoparticle-based controlled ACPA release system on endometrial cancer in an in vivo animal model using quantum dot marking, TUK-2019-17748
• Development of Bone Marrow Targeted Endocannabinoid Loaded Nanoparticle Carrier System and In Vitro Analysis, TÜBİTAK 119S182
• "Designing and In Vitro - In Vivo Evaluation of Ocular Drug Delivery Platforms for the Delivery of Riboflavin to the Cornea with Non-Invasive (Epi-On) Technique in the Treatment of Keratoconus"
• "Development and Evaluation of Besifloxacin HCl Loaded Ocular Inserts for the Treatment of Bacterial Keratitis by Electrospinning Method 217S126"
• "Development and optimization of pH Sensitive mesoporous silica nanoparticles with different sizes for use in breast cancer treatment and evaluation of their efficacy by in vitro tests, THD-2016-12890"
• "Investigation of Influence of Diabetes on Drug Absorption and Permeability, 9962"
• "Antibiotic Containing Dry Powder Inhaler Formulation Design and Permeability Studies TDK-2017-14493"
• "In vivo evaluation of nanocrystalline formulations developed to provide dose proportionality of the antiloagulant rivaroxaban with a bioavailability study in rabbits THD- 2017-13071"
• "Nanopharmaceuticals Design and In Vitro Evaluation of Nanoscale Drug Delivery Systems for Active Targeting in Breast Cancer Treatment THD-2017-11642"
• "Nanopharmaceuticals Design and In Vivo/In Vivo Evaluation of Nanoscale Drug Delivery Systems for Active Targeting in Breast Cancer Treatment TDK-2017-15964"
• "Antibiotic Containing Dry Powder Inhaler Formulation Design and Permeability Studies TDK-2017-14493"
• "In vivo evaluation of nanocrystalline formulations developed to provide dose proportionality of the antiloagulant rivaroxaban with a bioavailability study in rabbits THD- 2017-13071"
• Investigation of possible antiproliferative and proapoptotic effects of cannabinoids mediated by CB receptors in non-small cell lung adenocarcinoma, TYL-2018-17387
• Investigation of the CB1 receptor-mediated antiproliferative and apoptotic effect of the controlled ACPA release system in endometrial cancer, TSA-2018-17032
• Investigation of antitumoral activity of paclitaxel loaded cyclodextrin nanoparticles, TSA-2017-14496
• Nanosponge: organic toxic molecules absorption, an innovative therapeutic approach to Chronical Kidney Disease, ERANET Incomera Project 9160037
• Investigation of the Effect of Cyclodextrin Nanoparticles on Different Cancer Cells with a Systems Biology Approach, TÜBİTAK 115S456
• Developing a Phytocosmetic Product Repairing Collagen Tissue in the Skin by Investigation of Mmps Inhibitory Activities, Antioxidant Capacities and SPF Values of Rumex Crispus Extracts and Secondary Metabolites, TÜBİTAK 214S147
• Tumor-Specific Drug Delivery with Targeted Amphiphilic Cyclodextrin Nanoparticles and In Vitro-In Vivo Evaluation, TÜBİTAK 112S538
• Development of Aprepitant Loaded Amphiphilic Cyclodextrin Nanoparticle and Nanocapsule Formulations for Increasing Oral Bioavailability and Evaluation of In Vitro-In Vivo, TÜBİTAK 216S773
• Preparation, Characterization and In Vitro Evaluation of Cyclodextrin Nanoparticle-Containing Formulations Carrying Anticancer and Antiviral Drugs for Local Chemotherapy of HPV-Related Cervical Cancer by Printing Technology, TÜBİTAK 114S793
• Şenel S, Oral mucosa for delivery of drugs, allergies and vaccines: where are we now? Current Drug Delivery, 2016. 13(2): 172 – 174.
• "Dencker, L., Tyden, E., Hellmann, K., Mochel, J., Senel, S., Vendrig, J.C., Lindeng, I.
• Schmerold, I., Position Paper: EUFEPS Network on Veterinary Medicines Initiative: An
• interdisciplinary forum to support Veterinary Pharmacology and promote the development of new pharmaceuticals for Animal Health, Eur. J. Pharm. sci. , 2016. 91: p. 1-7"
• "Ates, M., M.S. Kaynak, and S. Sahin, Effect of permeability enhancers on paracellular
• permeability of acyclovir. J Pharm Pharmacol, 2016. 68(6): p. 781-90."
• "Cetin, M. and S. Sahin, Microparticulate and nanoparticulate drug delivery systems for
• metformin hydrochloride. Drug Deliv, 2016. 23(8): p. 2796-2805."
• Gulsun, T. and S. Sahin, Development and Validation of a RP-HPLC Method for Simultaneous Determination of Metformin Hydrochloride, Phenol Red and Metoprolol Tartrate for Intestinal Perfusion Studies. Latin American J Pharmacy 2016. 35(1): p. 50-57.
• "Gurbuz, M.U., Öztürk K., Ertürk A.Ş., Yöyen-Ermiş, D., Esendağlı, G., Çalış, S., Tülü, M.
• Cytotoxicity and biodistribution studies on PEGylated EDA and PEG cored PAMAM dendrimers, Journal of Biomaterials Science, Polymer Edition, 2016. 27 (16): p. 1645-1658."
• "Devrim, B., A. Kara, İ. Vural, and A. Bozkır, Lysozyme-loaded lipid-polymer hybrid
• nanoparticles: preparation, characterization and colloidal stability. drug
• development and industrial pharmacy, 2016. 42(11): p. 1865-1876"
• "Erdoğar, N., Esendağlı, G., Nielsen, TT., Şen, M., Öner, L., Bilensoy, E. Design and optimization
• of novel paclitaxel-loaded folate-conjugated amphiphilic cyclodextrin nanoparticles, Int. J.
• Pharm., 2016. 509(1-2): p.375-390."
• "Yavuz, B., S. Bozdağ Pehlivan, B. Sümer Bolu, R. Nomak Sanyal, İ. Vural, and N. Ünlü.
• Dexamethasone–PAMAM dendrimer conjugates for retinal delivery: preparation,
• characterization and in vivo evaluation. Journal of Pharmacy and Pharmacology, 2016. 68(8):
• p. 1010-1020."
• Yıldız S., Aytekin E., Yavuz B., Bozdağ Pehlivan S., Ünlü N. Formulation studies for mirtazapine orally disintegrating tablets. Drug Development and Industrial Pharmacy, 2016. 42(6):p. 1008-1017
• "Haidar, M.K. and H. Eroglu, Nanofibers: New Insights for Drug Delivery and Tissue
• Engineering. Curr Top Med Chem, 2017. 17(13): p. 1564-1579."
• "Guler, G.K., H. Eroglu, and L. Oner, Development and formulation of floating tablet
• formulation containing rosiglitazone maleate using Artificial Neural Network. Journal of Drug Delivery Science and Technology, 2017. 39: p. 385-397."
• Erdoğar, N., Işık, G., Bilensoy, E., ”Amphiphilic Cyclodextrin Derivatives for Targeted Drug Delivery to Tumors” Curr Top Med Chem, 17:1-8 (2017)
• Erdoğar, N., Esendağlı, G., Nielsen, TT, Esendağlı-Yılmaz, G., Yöyen-Ermiş, D., Erdoğdu, B., Sargon, MF, Eroğlu, H., Bilensoy, E., Therapeutic Efficacy of Folate Receptor-Targeted Amphiphilic Cyclodextrin Nanoparticles as a Novel Vehicle For Paclitaxel Delivery In Breast Cancer, Journal of Drug Targeting, DOI 10.1080/1061186X.2017.1339194
• "Varan, G., Varan, C., Erdoğar, N., Hıncal, A.A., Bilensoy, E., Amphiphilic Cyclodextrin
• Nanoparticles, International Journal of Pharmaceutics Special Issue, 531(2):457-469, 2017 "
• Varan, C., Bilensoy, E., Cationic PEGylated polycaprolactone nanoparticles carrying postoperative docetaxel for glioma treatment, Beilstein Journal Of Nanotechnology, 2017, 2190-4286, 8, 1446-1456.
• Varan, G., Mellet, C.O., Benito, J.M., Bilensoy, E., Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery, Beilstein Journal Of Nanotechnology, 2017, 2190-4286, 8, 1457-1468.
• Orgul D., Eroglu H., and Hekimoglu H., Formulation and characterization of tissue scaffolds containing simvastatin loaded nanostructured lipid carriers for treatment of diabetic wounds. Journal of Drug Delivery Science and Technology, 2017. 41: p. 280-292
• Akdag Cayli, Y., S. Şahin, F. Buttini, A.G. Balducci, S. Montanari, I. Vural, and L. Oner, Dry powders for the inhalation of ciprofloxacin or levofloxacin combined with a mucolytic agent for cystic fibrosis patients. Drug Development and Industrial Pharmacy, 2017. 43(8): p. 1378-1389
• Gulsun, T., N. Ozturk, M. Kaynak, I. Vural, and S. Sahin, Preparation and evaluation of furosemide containing orally disintegrating tablets by direct compression. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 2017. 72(7): p. 389-394.
• Kaffashi, A., et al., Farnesylthiosalicylic acid-loaded lipid–polyethylene glycol–polymer hybrid nanoparticles for treatment of glioblastoma. Journal of Pharmacy and Pharmacology, 2017.
• Ozturk, N., A. Kara, and I. Vural, Evaluation of antitumor activity of a non-steroidal antiinflammatory drug, ibuprofen, by a targeted nanoparticulate system. Latin American Journal of Pharmacy, 2017. 36(1): p. 44-52
• Sekerdag, E., et al., A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles. Journal of Controlled Release, 2017. 261: p. 187-198.
• Timur, S.S., P. Bhattarai, R.N. Gursoy, I. Vural, and B.-A. Khaw, Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-1 in Human Breast Cancer. Pharmaceutical research, 2017. 34(2): p. 352-364.
• Yıldız, S., E. Aytekin, B. Yavuz, S. Bozdağ Pehlivan, İ. Vural, and N. Ünlü, Development and evaluation of orally disintegrating tablets comprising taste-masked mirtazapine granules.Pharmaceutical Development and Technology, 2017: p. 1-8
• Karabey-Akyurek, Y., et al., An Improved and Validated HPLC Method for the Determination of Methylprednisolone Sodium Succinate and its Degradation Products in Nanoparticles. Current Pharmaceutical Analysis, 2017(13(2)): p. 162-168.
• Karabey-Akyurek, Y., et al., Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model. Pharm Dev Technol, 2017. 22(8): p. 972-981.
• Demirturk, E., et al., Preparation and In Vitro/In Vivo Evaluation of Rofecoxib Containing Bovine Serum Albumin Microspheres. Latin American Journal of Pharmacy, 2017. 36: p. 6.
• "Timur SS, Şahin A, Aytekin E, Öztürk N, Polat KH, Tezel N, Gürsoy RN, Çalış S. Design and In
• in vitro Evaluation of Tenofovir–Loaded Vaginal Gels for the Prevention of HIV Infections. Pharmaceutical Development and Technology. 2017 May 11(just-accepted)::1-22."
• "Orunoğlu M, Kaffashi A, Bozdağ Pehlivan S, Şahin S, Söylemezoğlu F, Karlı Oğuz K, Mut M.
• “Effects of curcumin-loaded PLGA nanoparticles on the RG2 rat glioma model” Materials Science and Engineering C, 78, 32-38, (2017)"
• Sarigol, E., et al., Design and evaluation of gamma-sterilized vancomycin hydrochlorideloaded poly(varepsilon-caprolactone) microspheres for the treatment of biofilm-based medical device-related osteomyelitis. Pharm Dev Technol, 2017. 22(6): p. 706-714.
• Sarıgöl E, Ekizoğlu M, Bozdağ Pehlivan S, Bodur E, Sağıroğlu M, Calis S. “A Novel Local Drug Delivery System Utilizing Thermosensitive Gel System Combined with Enzyme, Antibiotic and Microspheres Against Periprosthetic Joint Infection” J Microencapsulation, 2017
• Ozturk, K., et al., Effective targeting of gemcitabine to pancreatic cancer through PEG-cored Flt-1 antibody-conjugated dendrimers. Int J Pharm, 2017. 517(1-2): p. 157-167.
• "Ozturk, K., et al., Preparation and in vitro evaluation of 5-fluorouracil-loaded PCL
• nanoparticles for colon cancer treatment. Pharm Dev Technol, 2017. 22(5): p. 635-641."
• Sema Çalış, Kıvılcım Öztürk-Atar, Tumor Targeting Strategies, Journal of Drug Research and Development, 3(1), 2017, Mini Review.
• Azeran, NS, Zazali, ND, Timur, SS, Özdoğan, AI, Ekizoğlu, M., Sheshala, R., Dua, K., Sahu, PS, Şenel, S., Moxifloxacin loaded chitosan gel formulations for the treatment of periodontal diseases, Journal of Polymer Materials, Vo. 34, 2017
• Sahin, A., et al., Evaluation of brain-targeted chitosan nanoparticles through blood-brain barrier cerebral microvessel endothelial cells. J Microencapsul, 2017: p. 1-8.
• Sahin, A., et al., A small variation in average particle size of PLGA nanoparticles prepared by nanoprecipitation leads to considerable change in nanoparticles' characteristics and efficacy of intracellular delivery. Artif Cells Nanomed Biotechnol, 2017: p. 1-11.
• Sahin, A., et al., Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles. Pharmazie, 2017. 79(2): p. 525-528
• Yuce, M. and Y. Capan, Development and Validation of HPLC analytical methods used for determination of assay, content uniformity and dissolution of immediate release candesartan cilexetil 32 mg tablets. Acta Poloniae Pharmaceutica - Drug Research, 2017. 74(2): p. 357-367.
• Wildoglu- Ciftci, Baysal I, Erikci A, Arica-Yegin B, Ucar G. Transforming growth factor-β3 (TGF-β3) loaded PLGA-b-PEG nanoparticles: Efficacy in preventing cardiac fibrosis induced by TGF-β1. J Drug Deliv Sci Technol. 2018;48:223-234.
• Demir H, Arica-Yegin B, Oner L. Application of an artificial neural network to predict dissolution data and determine the combined effect of pH and surfactant addition on the solubility and dissolution of the weak acid drug etodolac. J Drug Deliv Sci Technol. 2018;47:215-222.
• Erdoğar N., Esendağlı G., Nielsen TT, Esendağlı-Yılmaz G., Yöyen-Ermiş D., Erdoğdu B., Sargon MF,Eroğlu H., Bilensoy E., Therapeutic Efficacy of Folate Receptor-Targeted Amphiphilic CyclodextrinNanoparticles as a Novel Vehicle for Paclitaxel Delivery in Breast Cancer, Journal of Drug Targeting, 2018,26(1):66-74.
• Öztürk-Atar K., Eroğlu H., Çalış S., Novel advances in Targeted Drug Delivery, Journal of Drug Targeting,26(8), 633-642, 2018
• Nemutlu E., Eroğlu İ., Eroğlu H., Kır S. In Vitro Release Test of Nano-drug Delivery Systems Based on Analytical and Technological Perspectives, Current Analytical Chemistry, 14, 1-37, 2018.
• Kara A, Ozturk N, Esendagli G, Ozkose U.U, Gulyuz S, Yilmaz O et al. Development of novel selfassembled polymeric micelles from partially hydrolysed poly(2-ethyl-2oxazoline)-co-PEI-b-PCL block copolymer as nonviral vectors for plasmid DNA in vitro transfection. Artificial Cells, Nanomedicine, and Biotechnology. 2018;46(53):5264-73
• Gulsun T, Bornaa S.E, Vural I, Sahin S. Preparation and characterization of furosemide nanosuspension. Journal of Drug Delivery Science and Technology. 2018;45:93-100
• Yıldız S, Aytekin E, Yavuz B, Pehlivan S.B, Vural İ, Ünlü N. Development and evaluation of orally disintegrating tablets comprising taste-masked mirtazapine granules. Pharmaceutical Development and Technology. 2018;23(5):488-95
• Kaplan M, Demiröz F.T, Vural İ, Çelebi N. Development and characterization of gels and liposomes containing ovalbumin for nasal deliver. Journal of Drug Delivery Science and Technology. 2018;44:108- 17
• Demir Kabaş H, Gülsün İnal T, Şener E, Şahin S, Öner L. Preparation and characterization of Rivaroxaban nanocrystals prepared by combination of wet ball milling and high pressure homogenization methods. Latin American Journal of Pharmacy. 2018;37(12):2482-90.
• Gülsün İnal T, Akdağ Çaylı Y, İzat N, Çetin M, Öner L, Şahin S. Development and evaluation of Terbutaline sulfate orally disintegrating tablets by direct compression and freeze drying methods. JDDST. 2018;6:251-58.
• Timur S.S., Yalcın G., Cevik O., Andac C., Gursoy R.N. Molecular Dynamics, Thermodynamic and Mutational Binding Studies for Tumor Specific LyP-1 in Complex with p32. Journal of Biomolecular Structure & Dynamics, Apr;36(5):1134-1144, 2018.
• Sarıgöl, E., Ekizoğlu, M., Pehlivan, S. B., Bodur, E., Sağıroğlu, M., & Calis, S.. A thermosensitive gel loaded with an enzyme and an antibiotic drug for the treatment of periprosthetic joint infection. Journal of Drug Delivery Science and Technology, 2018; 43, 423-429
• Ozdogan, A I., Akça, G, Senel, S. Development and in vitro evaluation of chitosan based system for local delivery of atorvastatin for treatment of periodontitis. European Journal of Pharmaceutical Sciences. 2018; 124, 208–216.
• Şenel, S., Comoglu, T. Orally disintegrating tablets, fast-dissolving, buccal and sublingual formulations. Pharmaceutical Development and Technology. 2018; 23(5), pp. 431.
• Özdoğan, A.I., İlarslan, Y.D., Kösemehmetoğlu, K., Akca, G., Kutlu, H.B., Comerdov, E. et al. In vivo evaluation of chitosan based local delivery systems for atorvastatin in treatment of periodontitis, International Journal of Pharmaceutics. 2018; 550(1-2), pp. 470-476
• Akca, G., Özdemir, A., Öner, Z.G., Şenel, S. Comparison of different types and sources of chitosan for the treatment of infections in the oral cavity, Research on Chemical Intermediates. 2018; 44(8), pp. 4811- 4825.
• Senel, S. An overview on veterinary drug delivery. Controlled Release Society Indian Chapter. 2018; 9, p. 15-22.
• Ercan A, Çelebier M, Varan G, Öncül S, Nenni M, Kaplan O, Bilensoy E. Global omics strategies to investigate the effect of cyclodextrin nanoparticles on MCF-7 breast cancer cells. EUR. J. Pharm. sci. 2018;123:377-386.
• Varan G, Patrulea V, Borchard G, Bilensoy E. Cellular interaction and tumoral penetration properties of cyclodextrin nanoparticles on 3D breast tumor model. nanomaterials. 2018;8(2):1-18.
• Mohammad KH, Demirbolat GM, Timur SS, Gürsoy RN, Nemutlu E, Ulubayram K, Öner L, Eroglu H. Atorvastatin-loaded nanosprayed chitosan nanoparticles for peripheral nerve injury. Bioinspired, Biomimetic and Nanobiomaterials. https://doi.org/10.1680/jbibn.19.00006
• Timur SS, Yoyen-Ermis D, Esendagli G, Yonat S, Horzum U, Esendagli G, Gursoy RN. Efficacy of a novel LyP-1-containing self-microemulsifying drug delivery system (SMEDDS) for active targeting to breast cancer. EUR. J. Pharm. biopharma 2019;136:138-146.
• Yagmur Akdag Cayli, Selma Sahin, Emirhan Nemutlu, Levent Oner, Determination of N-acetylcysteine in thepresence of ciprofloxacin or levofloxacin in microparticulate dry powder inhalers. Turk J Chem. 2019:43: 846 – 856.
• Onur Pınarbaslı, Selma Sahin, Hakan Eroglu, Levent Oner. Preparation and Evaluation of Phosphate Binding Capacity of Micronized Lanthanum Carbonate Formulation. Journal of Drug Delivery Science and Technology 2019:53: 101183
• Timur, S. S., Yüksel, S., Akca, G., Şenel, S. Localized drug delivery with mono and bilayered mucoadhesive films and wafers for oral mucosal infections. International Journal of Pharmaceutics. 559. pp. 102-112, 2019.
• Tonbul H, Sahin A, Tavukcuoglu E, Esendagli G, Capan Y. Combination drug delivery with actively-targeted PLGA nanoparticles to T overcome multidrug resistance in breast cancer. Journal of Drug Delivery Science and Technology. 2019; 54, 101380
• Varan C., Şen M., Sandler N., Aktaş Y., Bilensoy E. Mechanical characterization and ex vivo evaluation of anticancer and antiviral drug printed bioadhesive film for the treatment of cervical cancer. Eur J Pharm Sci. 2019; 130:114-123
• Erdoğar N., Nemutlu E., İskit AB., Kara SC., Teksin ZŞ., Bilensoy E. Improved oral bioavailability of anticancer drug tamoxifen through complexation with water soluble cyclodextrins: in vitro and in vivo evaluation. J Inc. Phenom Macro. 2019
• Orhan E., Aka İ.Ö., Yüzbaşıoğlu M., Yavuz B., Bilensoy E., Uz A.K. The Effect of Quercus coccifera L. Extract on the Necrosis of Random-pattern Skin Flaps in Rats. Medical Bulletin of Haseki. 2019; 57(3): 249-254
• Nemutlu E., Eroğlu İ., Eroğlu H., Kır S. In Vitro Release Test of Nano-drug Delivery Systems Based on Analytical and Technological Perspectives, Current Analytical Chemistry, 2019; 15: 373-409.
• Öztürk-Atar K., Eroğlu H., Gürsoy R.N. Calis S., Current Advances in nanopharmaceuticals, Journal of Nanoscience and Nanotechnology, 2019; 19(7): 3686-3705.
• Karakucuk A., Teksin Z.S., Eroglu H., Celebi, N., Evaluation of improved oral bioavailability of ritonavir nanosuspension, European Journal of Pharmaceutical Sciences, 2019; 131:153-158
• Tezel G., Timur SS, Bozkurt İ., Türkoğlu OF, Eroğlu İ., Nemutlu E., Öner L., Eroğlu H. A Snapshot on the Current Status of Alzheimer's Disease, Treatment Perspectives, In-Vitro and In-Vivo Research Studies and Future Opportunities, Chemical and Pharmaceutical Bulletin,2019; 67:1030-1041
• Gökbulut E, Vural I, Aşıkoğlu M, Ozdemir M. Floating drug delivery system of itraconazole: in vitro and in vivo studies. Journal of Drug Delivery Science and Technology. 2019;49:491-501
• Al-Heibshy F.N.S, Başaran E, Arslan R, Oztürk N, Vural I, Demirel M. Preparation, characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated cyclodextrin-polyanhydride nanoparticles. Drug Development and Industrial Pharmacy. 2019;45(10):1635-1645
• Gülsün T, Akdağ Y, Izat N, Öner L, Şahin S. Effect of particle size and surfactant on the solubility, permeability and dissolution characteristics of deferasirox. JRes Pharm. 2019; 23(5): 851-859.
• Barenji R.V., Akdag Y., Yet B., Oner L. Cyber-physical-based PAT (CPbPAT) framework for Pharma 4.0. Int J Pharmaceut. 2019; DOI: 10.1016/j.ijpharm.2019.06.036.
• Akdag Y, Gulsun T, Izat N, Oner L, Sahin S. Comparison of Dissolution Profiles and Apparent Permeabilities of Commercially Available Metformin Hydrochloride Tablets in Turkey. Dissolut Technol. 2020;27(1):22-29.
• Akdag Y, Gulsun T, Izat N, Cetin M, Oner L, Sahin S. Characterization and Comparison of Deferasirox Fast Disintegrating/Dissolving Tablets Prepared by Direct Compression and Lyophilization Methods. J Drug Deliv Sci Technol. 2020;57:101760.
• Demirtürk E, Nemutlu E, Sahin S, Oner L. Development and Validation of an HPLC Method for Determination of Rofecoxib in Bovine Serum Albumin Microspheres. Turkish J Chemistry. 2020;44(3):647-655.
• Gulsun T, Akdag Y, Izat N, Cetin M, Oner L, Sahin S. Development and Characterization of Metformin Hydrochloride and Glyburide Containing Orally Disintegrating Tablets. Pharm Dev Technol. 2020;25(8):999-1009.
• Demir H, Gulsun T, Ozkan M.H, Nemutlu E, Sahin S, Oner L. Assessment of Dose Proportionality of Rivaroxaban Nanocrystals. AAPSSciTech. 2020;21(6):228.
• Haidar MK, Demirbolat GM, Timur SS, Gürsoy RN, Nemutlu E, Ulubayram K, Öner L, Eroğlu H. Atorvastatin-loaded Nanosprayed Chitosan Nanoparticles for Peripheral Nerve Injuries, Bioinspired Biomimetic and Nanobiomaterials. 2020;9(2), 74-84.
• Haidar MK, Timur SS, Demirbolat GM, Nemutlu E, Gürsoy RN, Ulubayram K, Öner L, Eroğlu H. Novel Electrospun Composite Nanofiber Formulation for Dual and Localized Delivery of Neuroprotective Drugs, Fibers and Polymers, 2020, Accepted, in press.
• Haidar MK, Timur SS, Kazanci A, Turkoglu OF, Gürsoy RN, Nemutlu E, Sargon MF, Bodur E, Gok M, Ulubayram K, Öner L, Eroğlu H. Composite Nanofibers Incorporating Alpha Lipoic Acid and Atorvastatin Provides Neuroprotection after Peripheral Nerve Injury in Rats, European Journal of Pharmaceutics and Biopharmaceutics, 2020;153:1-13.
• Tezel G, Timur SS, Kuralay F, Gursoy RN, Ulubayram K, Oner L, Eroglu H. Current Status of Micro/Nanomotors in Drug Delivery, Journal of Drug Targeting, 2020, https://doi.org/10.1080/1061186X.2020.1797052,
• Gurcan O, Uckun MO, Celikmez MC, Turkoglu OF, Eroglu H, Beskonaklı E. ve ark. Neuroprotective Efficiency of Cyclosporine After Traumatic Brain Injury in Rats. Turkish Neurosurgery. 2020; 30(4):507-512.
• Ozturk K, Arslan, FB, Tavukcuoglu E, Esendagli G, Calis S. Aggregation of chitosan nanoparticles in cell culture: Reasons and resolutions. International Journal of Pharmaceutics. 2020; 578, Article Number: 119119.
• Aytekin E, Ozturk N, Vural I, Polat HK, Cakmak HB, Calis S, ve ark. Design of ocular drug delivery platforms and in vitro - in vivo evaluation of riboflavin to the cornea by non-interventional (epi-on) technique for keratoconus treatment. Journal of Controlled Release. 2020; 324: 238-249.
• Polat HK, Bozdag Pehlivan S, Ozkul C, Calamak S, Ozturk N, Aytekin E ve ark. Development of besifloxacin HCl loaded nanofibrous ocular inserts for the treatment of bacterial keratitis: In vitro, ex vivo and in vivo evaluation. International Journal of Pharmaceutics. 2020; 585, Article Number: 119552.
• Yüksel S, Pekcan M, Puralı N, Esendağlı G, Tavukçuoğlu E, Rivero-Arredondo V ve ark. Development and in vitro evaluation of a new adjuvant system containing Salmonella Typhi porins and chitosan. Int J Pharm. 2020. 578. 119129.
• Şenel S. Nanotechnology and Animal Health. Pharm. Nanotechnol. 2020. 8. 1-14.
• Şenel S, Yüksel S. Chitosan-based particulate systems for drug and vaccine delivery in the treatment and prevention of neglected tropical diseases. Drug Deliv. Transl. Res. 2020. 10(6). 1644-1674.
• Şenel S. Current status and future of chitosan in drug and vaccine delivery. React Funct Polym. 2020. 147. 104452.
• Uzunoğlu B, Wilson C G, Sağıroğlu M, Yüksel S, Şenel S. Mucoadhesive bilayered buccal platform for antifungal drug delivery into the oral cavity. Drug Deliv. Transl. Res. 2020.
• Özdoğan AI, Akca G, Şenel S. Development and in vitro evaluation of gel formulation of atorvastatin solid dispersions. J Drug Deliv Sci Technol. 2020. 102199.
• Kayıran Çelebier S, Bozdaǧ Pehlivan S, Demirbilek M, Akinci M, Vural İ, Akdaǧ Y, ve ark. Development of an Anti-Inflammatory Drug-Incorporated Biomimetic Scaffold for Corneal Tissue Engineering. Journal of Ocular Pharmacology and Therapeutics. 2020;36(6):433-46.
• Caban-Toktas S, Sahin A, Lule S, Esendagli G, Vural I, Karlı Oguz K, ve ark. Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. International Journal of Pharmaceutics. 2020;578.
• Ozturk N, Kara A, Gulyuz S, Ozkose UU, Tasdelen MA, Bozkir A, ve ark. Exploiting ionisable nature of PEtOx-co-PEI to prepare pH sensitive, doxorubicin-loaded micelles. Journal of Microencapsulation. 2020:1-14.
• Varan C, Anceschi A, Sevli S, Bruni N, Giraudo L, Bilgiçe E, Korkusuz P ve ark. Preparation and characterization of cyclodextrin nanosponges for organic toxic molecule removal. International Journal of Pharmaceutics. 2020; 585
• Ünal S, Aktaş Y, Benito JM, Bilensoy E. Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization. International Journal of Pharmaceutics. 2020; 584
• Varan G, Akkın S, Demirtürk N, Benito JM, Bilensoy E. Erlotinib entrapped in cholesterol-depleting cyclodextrin nanoparticles shows improved antitumoral efficacy in 3D spheroid tumors of the lung and the liver. Journal of Drug Targeting. 2020, DOI: 10.1080/1061186X.2020.1853743
• Boyacıoğlu Ö, Bilgiç E, Varan C, Bilensoy E, Nemutlu E, Sevim D, ve ark. ACPA decreases non-small cell lung cancer line growth through CB1 receptor-mediated Akt/PI3K and JNK pathways in vitro, Cell Death Dis. 2020 https://doi.org/10.1038/s41419-020-03274-3
• Gencer A, Duraloglu C, Ozbay S, Ciftci TT, Yabanoglu-Ciftci S, Arica B. Recent advances in treatment of lung cancer: nanoparticle-based drug and siRNA delivery systems. Current Drug Delivery. 2020; 17
• Erdoğar N, Nemutlu E, İskit AB, Kara SC, Teksin ZŞ, Bilensoy E. Improved Oral Bioavailability of Anticancer Drug Tamoxifen Through Complexation with Water Soluble Cyclodextrins: In Vitro and In Vivo Evaluation. J Incl Phenom and Macrocycl Chem. 2020;96:81-91.
• Varol I, Kaplan O, Erdoğar N, Öncül S, Nielsen TT, Ercan A, Bilensoy E, Çelebier M. Q-TOF LC/MS-based Untargeted Metabolomics Approach to Evaluate the Effect of Folate-Conjugated Cyclodextrins on Triple-Negative Breast Cancer Cells. Curr Pharm Anal. 2020, E-pub Ahead of Print
• Varol I, Kaplan O, Erdoğar N, Öncül S, Nielsen TT, Ercan A. ve ark. Folate-Conjugated Cyclodextrins Directly Intervene the Energy Metabolism in Triple Negative Breast Cancer Cells: An Untargeted Metabolomics Study, Current Pharm. Analysis. 2020, (accepted October 2020) DOI: 10.2174/1573412917999201020205745
• Timur SS, Gürsoy RN. Design and in vitro evaluation of solid SEDDS for breast cancer therapy, Journal of Drug Delivery Science and Technology, ISSN: 1773-2247, Vol: 60, Page: 102023, 2020
• Bal E, Hanalıoğlu S, Köprü C, Köse S, Basak A, Bozdağ Pehlivan S, ve ark. Effect of mesenchymal stem cells therapy in experimental kaolin induced syringomyelia model, J Neurosurg Sc, 2020; Oct 15: Epub
• Aytekin E, Bozdağ Pehlivan S. Corneal Cross-Linking Approaches on Keratoconus Treatment Running Head: Is Epi-On Method a Step in the Right Direction, J DRUG DELIV SCI TEC, (In Press)
• Örgül D, Eroğlu H, Tiryaki M, Alpaslan Pinarli F, Hekimoğlu S. In-Vivo Evaluation of Tissue Scaffolds Containing Simvastatin Loaded Nanostructured Lipid Carriers and Mesenchymal Stem Cells in Diabetic Wound Healing, Journal of Drug Delivery Science and Technology, 2020, https://doi.org/10.1016/j.jddst.2020.102140.
• Ozturk-Atar K, Kaplan M, Calis S. Development and evaluation of polymeric micelle containing tablet formulation for poorly water-soluble drug: tamoxifen citrate. Drug Development and Industrial Pharmacy. 2020; 46(10): 1695-1704.
• Türkmen E, Şenel S. Applications of Phages in Antimicrobial Therapy. J Lit Pharm Sci. 2020.
• Öztürk N, Kara A, Vural İ. Formulation and in vitro evaluation of telmisartan nanoparticles prepared by emulsion-solvent evaporation technique. Turkish Journal of Pharmaceutical Sciences. 2020;17(5):492-9.
• Çelebier M, Nenni M, Kaplan O, Akgeyik E, Kaynak M.S, Altınöz S, Şahin S, Determination of the physicochemical properties of piroxicam. Turk J Pharm Sci. 2020;17(5):535-541.
• Akdag Y, Gulsun T, Izat N, Cetin M, Oner L, Sahin S, Evaluation of preparation methods for orally disintegrating tablets. MedScience. 2020; 9(1):259-263.
• Gulsun T, Sahin S, Evaluation of drug permeability methods recommended by health authorities. MedScience. 2020;9(1):255-258.
• Demir B, Timur SS, Gürsoy RN, Parfümler: Formülasyonları, Dünü, Bugünü ve Yarını, Hacettepe University Journal of the Faculty of Pharmacy 2020;40(1):20-33.
• Şenel S, Derici MK, Devrim B, Regulatory Aspects of Vaccines, FABAD J. Pharm. sci. 2020. 45 (2).
• Gencer A, Akgeyik E, Kaynak M.S, Celebier M, Sahin S, Assesment of pharmaceutical quality of extended release metoprolol tartrate tablets available in Turkish drug market. Eskişehir Technical University Journal of Science and Technology A- Applied Sciences and Engineering. 2020;9(2):179-189.
• Çopur T, Bozdağ Pehlivan S, Öner L, Migren Tedavisinde Nanoteknoloji Temelli İlaç Taşıyıcı Sistemler, Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, (Basımda)