Physiology Department Research Laboratories

About Research Infrastructure Researchers Ongoing Projects Completed Projects Publications Links

About

Physiology Department Research Laboratories consist of molecular physiology and cell culture laboratory, isolated organ laboratory, hemorheology laboratory, neurophysiology laboratory, behavioral experiments laboratory, molecular imaging laboratory, operating room for experimental animals and a student laboratory. Research carried out in the laboratories of the Department of Physiology covers all areas of physiology, from studies at the molecular and cellular level to the functional integration of various organ systems. In the studies carried out in our laboratories, traditional research methods and many new cellular and molecular techniques are used together to elucidate the physiological mechanisms and physiopathological basis of diseases. In our department, research studies are carried out mainly on molecular physiology, electrophysiology, neurophysiology, hemorheology, mitochondrial physiology, cardiovascular physiology, neuroendocrinology and obesity.

Studies carried out include research conducted by faculty members as well as graduate and doctorate students and academic staff who have completed their specialization and doctorate education. Multidisciplinary studies are given great importance in our department and members of the department collaborate with different departments and universities during most of the research studies. The Department of Physiology also promotes researcher-oriented student training programs that will contribute to education, scientific research and dissemination of knowledge in physiological sciences. For this purpose, summer internships are organized in the laboratories of our Department in order to support the research infrastructure of undergraduate students, especially the students of the Faculty of Medicine.

Research Infrastructure

• Cold room and cooling system
• Laminar flow
• Fume hood
• Oil compressor
• Piston air compressor
• Oil compressor
• Vacuum compressor
• Day care room and cages
• Freezers 2-4 ⁰C; -20⁰C; -80⁰C
• pH meter
• Viscometer
• Oven
• Uncooled centrifuge flat and micro
• Aqueous spirometer
• Telethermometer
• MP30 Computerized data acquisition and analysis system
• Electrocardiograph
• Glass materials
• Surgical Supplies
• Faraday cage
• Eeg registration system
• Eeg warning system
• Mettler- Toledo brand S 2104 model pH meter
• 9157BN pH/ ATC electrode for Orion 420A pH meter
• Laser Optical Rotational Cell Analyzer
• Kon-plate type viscometer
• ROTEM Rotational Thromboelastogram
• MP 100 Bipopac computerized data acquisition analysis unit and modules
• MP 36 Biopac computerized data acquisition analysis unit
• Vibration-free table
• Injector pump
• Precision balance
• Vortex
• Stimulator Grass S88
• Homogenizer
• Elisa reader
• O2/CO2 tube and cap
• Isolated organ bath set and transducers
• Analytical balance
• Invert Microscope
• CO2 Incubator
• Snow Maker
• Deionized Water Device
• Shaking Water Bath
• Liquid Nitrogen Tank and Dewor Container
• Refrigerated Centrifuge
• Magnetic Stirrer
• UV Spectrophotometer
• Western Blot Imaging System
• Electrophoresis Power Supply and Systems
• Histoline semi-motorized frozen device
• Ultrasonic homogenizer
• Fluorescent attachment for microscope
• Leica dm2000led research microscope with fluorescent attachment
• Manual stereotaxic injector
• Microdrill
• Stereotaxic device
• Mixer (centrifuge)

Researchers

Prof. Dr. Bilge Pehlivanoğlu (Head of the Department)
Prof. Dr. Neslihan H. DİKMENOĞLU FALKMARKEN
Prof. Dr. Ayşen ERDEM
Prof. Dr. Meltem TUNCER
Doç. Dr. Esin İLERİ GÜREL
Doç. Dr. Okan ARIHAN
Doç. Dr. Hilal KORKMAZ
Dr. Öğr. Üyesi Serkan KARAİSMAİLOĞLU
Dr. Öğr. Üyesi Aslı Şan DAĞLI GÜL
Dr. Öğr. Üyesi Nazlı KARİMİ
Öğr. Gör. Dr. Ahmet Onur DAŞTAN
Öğr. Gör. Dr. Simay ALCAN
Öğr. Gör. Dr. Kamran HAGHIZADE
Uzm. Dr. Mustafa GÖRMÜŞ
Arş. Gör. Dr. Özbeyen ATALAY
Arş. Gör. Dr. Kübra BULUT
Arş. Gör. Dr. Ayşe Kübra IŞIK
Arş. Gör. Esra Nur ALKAN

Ongoing Projects

The Relationship Between Functional and Structural Connectivity and GJA1 Gene Single Nucleotide Polymorphisms in Alzheimer's Patients- Prof. Dr. Bilge PEHLİVANOĞLU
The Protective Effect of Dapagliflozin on Intestinal Ischemia-Reperfusion Injury- Assoc. Prof. Esin İLERİ GÜREL
The Effect of Caffeine and Glucose Consumption on Prefrontal Cortex Activity and Cognitive Performance- Assist. Prof. Serkan KARAİSMAİLOĞLU
The Measurement of CRP, IL-17, and IL-19 Levels in Serum and Saliva of Patients with Acne Vulgaris- Assist. Prof. Nazlı KARİMİ

Completed Projects

Investigation of the Antihypertensive Effect of Hesperidin and Aerobic Exercise in L-NAME Induced Hypertensive Rats - Prof. Dr. Ayşen Erdem
Comparison of the Effects of Mitochondria Transplantation and Exercise in an Experimental Parkinson's Disease Model - Prof. Dr. Meltem Tuncer
Effects of Mitotempo on Trigeminal Ganglion Mitochondrial Dysfunction in an Experimental Migraine Model - Prof. Dr. Meltem Tuncer
The Effect of Hacettepe Solution on Ischemia Reperfusion Injury with an Extracorporeal Circulation System - Prof. Dr. Bilge Pehlivanoğlu
Recognizing Social Hierarchy in Schizophrenia - Prof. Dr. Bilge Pehlivanoğlu
The Relationship Between Functional and Structural Connectivity and Gja1 Gene Single Nucleotide Polymorphisms in Alzheimer's Patients - Prof. Dr. Bilge Pehlivanoğlu
Effects of Low and High Doses of Caffeine on Anxiety Created Using Virtual Reality - Prof. Dr. Bilge Pehlivanoğlu
The Effect of Taurine on Tumor Size and Metastasis in Triple-Negative Breast Cancer Treated with Doxorubicin - Prof. Dr. Ayşen Erdem
Protective Effect of Intermittent Fasting on Biochemical, Histopathological and Behavioral Parameters in Diabetic Rats Exposed to Acrylamide - Prof. Dr. Ayşen Erdem
High-Resolution Microscopic Examination of Deep Structures of Tissue and Live Animals Using Multiphoton Microscopy - Prof. Dr. Ayşen Erdem
Anxiolytic Effect of Salvia heldreichiana (Footed Sage) in Single and Repeated Doses on Rats - Prof. Dr. Ayşen Erdem
The Effect of Platelet-Rich Fibrin on Colon Anastomosis - Prof. Dr. Ayşen Erdem
Investigation of the Synergistic Effects of Stattic and Paclitaxel on Proliferation and Metastasis in Triple-Negative Breast Cancer - Prof. Dr. Ayşen Erdem
The Effect of Empagliflozin on Doxorubicin-Induced Cardiomyopathy in Rats - Prof. Dr. Ayşen Erdem
The Effect of Empagliflozin on Sotalol-Induced QT Prolongation - Prof. Dr. Ayşen Erdem
Conducting "In Silico" Experiment Simulation in the Medical Faculty Physiology Student Laboratory - Prof. Dr. Ethem Gelir
Optical Monitoring of Cerebral Blood Flow and Metabolism During Carotid Endarterectomy - Prof. Dr. Ethem Gelir
The Effect of Short- and Long-Acting Somatostatin Analogues, Octreotide and Lanreotide, in Protecting Ovarian Damage in a Rat Ischemia-Reperfusion Model - Prof. Dr. Meltem Tuncer
The Effect of Melatonin and Metformin in Protecting Ovarian Damage in a Rat Ischemia-Reperfusion Model - Prof. Dr. Meltem Tuncer
Investigation of the Effects of Melatonin on Membrane ATPase Activities and Ultrastructurally on White and Gray Matter in Forebrain Ischemia-Reperfusion Injury - Prof. Dr. Meltem Tuncer
Demonstration of Transplacental Passage of Mitochondria Isolated from Rat Mesenchymal Stem Cells from Mother to Offspring - Prof. Dr. Meltem Tuncer
Imaging of the Biodistribution of Mitochondria After Mitochondrial Transplantation - Prof. Dr. Meltem Tuncer
Investigation of the Effects and Signaling Pathways of Isolated Mitochondria Transplantation in a COVID-19-Like Acute Respiratory Distress Syndrome Model in Rats - Prof. Dr. Meltem Tuncer
Effects of Mitochondrial Transplantation and Exercise in an Experimental Skeletal Muscle Atrophy Model Induced by Doxorubicin - Prof. Dr. Meltem Tuncer
The Effect of Melatonin on Cisplatin-Induced Neurotoxicity in Rats - Prof. Dr. Meltem Tuncer
Preparation, Characterization, and In Vivo Evaluation of the Efficacy of Orally Disintegrating Mini Tablet Formulations Containing Atomoxetine Using Quality by Design (QbD) System in the Treatment of Attention Deficit and Hyperactivity Disorder - Prof. Dr. Bilge Pehlivanoğlu
Investigation of the Effect of Fospropofol on Vascular Smooth Muscle - Prof. Dr. Bilge Pehlivanoğlu
Investigation of the Effect of Sulodexide on Vascular Smooth Muscle - Prof. Dr. Bilge Pehlivanoğlu
The Effect of Oxytocin on the Neural Response to Different Fearful Stimuli in Humans: The Role of Interpersonal Genetic Variations - Prof. Dr. Bilge Pehlivanoğlu
Investigation of the Effect of Body Weight on Motor Skills and Its Relationship with Central Dopamine and Dopamine Receptor Levels in a Rat Model of Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu
Investigation of the Role of the Complement System and Its Modulation by Catechin in the Neuroinflammation Process of Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu
Effect of Myosin Light Chain Kinase Inhibitor ML7-Loaded Nanofiber Polymers on Myometrial Contraction - Prof. Dr. Bilge Pehlivanoğlu
An Extracorporeal Circulation Model for Solving the Long Ischemia Problem During Transplantation and Replantation - Prof. Dr. Bilge Pehlivanoğlu
In Vivo Investigation of the Efficacy of Different Combinations of Quercetin, Silibinin, and Epigallocatechin Gallate in the Treatment of 4T1 Breast Cancer - Prof. Dr. Bilge Pehlivanoğlu
Preparation, Characterization, and In Vivo Evaluation of the Efficacy of Brain-Targeted, Wheat Germ Agglutinin (WGA)-Conjugated PLGA Nanoparticles in Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu
Evaluation of Systemic and Pulmonary Hypertension, Cardiac Functions, and the Factors Affecting Them in Pre- and Post-Adenoidectomy Periods in Children with Adenotonsillar Hypertrophy and Obstructive Sleep Apnea - Prof. Dr. Bilge Pehlivanoğlu
The Effect of Oxytocin on the Neural Response to Different Fearful Stimuli in Humans: The Role of Interpersonal Genetic Variations - Prof. Dr. Bilge Pehlivanoğlu (Bu madde 29 ile aynıdır)
Investigation of the Role of Telocyte Cells in the Fallopian Tube in the Pathogenesis of Ectopic Pregnancy - Prof. Dr. Bilge Pehlivanoğlu
Extraocular Muscle Regeneration with Decellularized Bovine Extraocular Muscle and PCL-Muscle Matrix Composite Tissue Scaffolds - Prof. Dr. Ayşen Erdem, Prof. Dr. Meltem Tuncer
Evaluation of the Effect of a Biological Conduit Model for Peripheral Nerve Defect Repair: A Nerve Conduit Model Containing De-Epithelialized Human Amniotic Membrane and Adipose-Derived Mesenchymal Stem Cell Layer on Nerve Healing - Prof. Dr. Ayşen Erdem, Prof. Dr. Meltem Tuncer
The Effect of Agmatine and L-Arginine on GLP-1 and PYY Secretion in Human NCI-H716 Cells: The Role of Calcium-Sensing Receptors (CaSR) - Doç. Dr. Esin İleri Gürel
Investigation of the Relationship Between Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB), Blood Glucose Level, and Hepatic Steatosis - Doç. Dr. Esin İleri Gürel
The Effect of Oral Caprylic Acid Administration on Acyl-Ghrelin and Growth Hormone Levels and Anxiety in Growing Rats - Doç. Dr. Esin İleri Gürel
The Effect of Methylprednisolone on Gentamicin-Induced Nephrotoxicity in Rats - Doç. Dr. Esin İleri Gürel
Investigation of the Biodistribution, Histopathological and Biochemical Effects of Silver Nanoparticles Functionalized by Coating with Three Different Biocompatible Polysaccharide Nanocomposites in Mice - Doç. Dr. Esin İleri Gürel
Investigation of Serum Obestatin and Ghrelin Levels in Girls Followed Up with a Diagnosis of Central Precocious Puberty - Doç. Dr. Esin İleri Gürel
Effects of Subacute Carvacrol Administration on Behavioral and Oxidative Stress Parameters During NAF Exposure - Doç. Dr. Okan Arıhan
Investigation of the Protective Effect of Carvacrol on Behavioral, Biochemical, and Metabolomic Parameters in Cadmium-Exposed Rats - Doç. Dr. Okan Arıhan
Investigation of the Anxiolytic Effect of Cocoa (Theobroma cacao) Applied at Different Doses and with Sucrose on Rats - Doç. Dr. Okan Arıhan
Investigation of the Effect of Isolated Mitochondria Transplantation on Renal Ischemia-Reperfusion Injury in Rats - Doç. Dr. Murat Timur Budak
Investigation of the Effect of Aromatase/Sirtuin-1 Interaction on miRNA Expression Levels in Cell Culture - Doç. Dr. Murat Timur Budak
The Role of Changes in Respiratory Functions, Exercise Capacity, and Quality of Life in Patients with Primary Ciliary Dyskinesia in Oxidant and Antioxidant Response - Doç. Dr. Murat Timur Budak
Effects of Silibinin on Langerhans Islets and Cognitive Functions in a Streptozotocin-Induced Rat Diabetes Model - Öğr. Gör. Dr. Aslı Şan Dağlı Gül
Investigation of the Effect of Salvia aytachii (Moon-shaped Sage) on Blood Glucose Levels in Streptozotocin-Induced Diabetic Rats - Öğr. Gör. Dr. Aslı Şan Dağlı Gül
Evaluation of the Effects of Different Cognitive Tasks on Sympathetic Responses: Implementation of a High-Precision, Low-Cost Complementary Method - Öğr. Gör. Dr. Nazlı Karimi
Investigation of the Expression Levels of Murf-1 and Atrogin-1 Genes and Redox Status in Atrophy Induced by Hydrogen Peroxide in Melatonin-Treated Mouse Myoblast Cell Line - Öğr. Gör. Dr. Nazlı Karimi

Publications

Savran OY, Tuncer M. “Possible role of novel mitochondrial subsets in migraine”. Life (Basel) 2025 15(8), 1273.
Yülek F, Akdere ÖE, Akbayrak SK, Gümüşderelioğlu M, Çaylı S, Alimoğulları E, Erdem A, Tuncer M, Atalay Ö. “Engineered Extraocular Muscle with Decellularized Tissue and Synthetic Biodegradable Polymers: Design, Properties, and In Vivo Studies” ACS Biomater Sci Eng 2025 SEP 8; 11(9):5482-5497.
Pehlivanoğlu B, Tuncer M, Doğan M. “Metformin Attenuates Spontaneous and Stimulated Myometrium Contractions in Rat Uterine Strips” Eurasian J Med 2025 57(3): 1-6.
Y. Karasu, M. Demeli Ertuş, D. Önal, B. Topçu, H. Eroğlu, B. Pehlivanoğlu. In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7. Eur Rev Med Pharmacol Sci 2024; 28 (5): 1891-1903. doi: 10.26355/eurrev_202403_35603.
Yildiz Y, Mutlu E, Arihan O, Yagcioglu AEA, Dikmenoglu Falkmarken NH. Investigation of hemorheological parameters in patients with major depressive disorder. Clin Hemorheol Microcirc. 2024;87(3):333-345. doi: 10.3233/CH-232061.
D. Önal, H. Korkmaz, G. Önal, B. Pehlivanoğlu. Body weight modulates the impact of oxytocin on chronic cold-immobilization stress response. Peptides 2024; 30;177:171202. doi: 10.1016/j.peptides.2024.171202.
Korkmaz H, Pehlivanoğlu B. Is Vitamin D a Crucial Molecule for Musculoskeletal and Cardiovascular Systems in Postmenopausal Women? Front Biosci (Landmark Ed). 2024; 29(8): 281. doi: 10.31083/j.fbl2908281.
Ö Atalay., ED Ozyilmaz, D Önal, D, B Pehlivanoğlu, TÇomoğlu. Development and In vivo Evaluation of Atomoxetine Hydrochloride ODMTs in a Nicotine-Induced Attention Deficit Hyperactivity Disorder (ADHD) Model in Rats. AAPS PharmSciTech 2024; 25, 173. https://doi.org/10.1208/s12249-024-02889-5.
Ors Yildirim N, Yildirim AK, Demeli Ertus M, Dastan AO, Pehlivanoglu B, Chi YW, Gianesini S, Doganci S, Yildirim V. Sulodexide Inhibits Arterial Contraction via the Endothelium-Dependent Nitric Oxide Pathway. J Clin Med. 2024; 13(8): 2332. doi: 10.3390/jcm13082332
Kubat GB, Tuncer M. Doxorubicin-dependent skeletal muscle atrophy: Exercise and mitochondrial dysfunction. Turkish Journal of Sports Medicine 2024 59(1): 39-43.
Kubat GB, Ulger O, Atalay O, Fatsa T, Turkel I, Ozerklig B, Celik E, Ozenc E, Simsek G, Tuncer M. The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy. Journal of Muscle Research and Cell Motility 2024 45:233–251. https://doi.org/10.1007/s10974-024-09676-6.
H Korkmaz, CD Deveci, Y Üstün, B Pehlivanoğlu. Comparison of plasma oxytocin level in women with natural and surgical menopause. Endocrine 2023;82(1):209-214. doi: 10.1007/s12020-023-03453-0.
Kartal Y, Tokat UM, Kelicen-Ugur P, Yılmaz S, Karahan S, Budak MT. Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells. Curr Mol Pharmacol. 2023;16(6):609-628. doi: 10.2174/1874467215666220510112118.
M Doğan, AM Sevgili, İ Kozanoğlu, B Pehlivanoğlu. Effect of acute or subchronic stress on T cell response in peripheral blood: Regulatory role of vitamin D. In J Exper Biol. 2023; 61. 14-24. doi: 10.56042/ijeb.v61i01.60922.
S Doğancı, ME İnce, M Demeli, N Örs-Yıldırım, B Pehlivanoğlu, AK Yıldırım, S Gianesini, YW Chi, V Yıldırım. Sulodexide Develops Contraction in Human Saphenous Vein via Endothelium-Dependent Nitric Oxide Pathway. J. Clin. Med. 2023, 12, 1019. https://doi.org/10.3390/jcm1203101.
Kubat, GB, Bouhamida, E, Ulger O, Turkel I, Pedriali G, Ramaccini D, Ekinci O, Ozerklig B, Atalay O, Patergnani S, Sahin BN, Morciano G, Tuncer M, Tremoli E, Pinton P. Mitochondrial Dysfunction and Skeletal Muscle Atrophy: Causes, Mechanisms, and Treatment Strategies. Mitochondrion 2023; 72:33-58. https://doi.org/10.1016/j.mito.2023.07.003
Tuncer M, Alcan S. Pyroptosis: a new therapeutic strategy in cancer. Mol Biol Rep 2023 50(7):6191-6200. https://doi.org/10.1007/s11033-023-08482-6.
Yılmaz MM, Akdere ÖE, Gümüşderelioğlu M, Bayrak GK, Koç S, Erdem A, Tuncer M, Atalay Ö, Kaplanoğlu GK, Akarca Dizakar SÖ, Calis M. Biological nerve conduit model with de-epithelialized human amniotic membrane and adipose-derived mesenchymal stem cell sheet for repair of peripheral nerve defects. Cell Tissue Res 2023; 391(3):505-522. https://doi.org/10.1007/s00441-022-03732-8.
Kayabekir M, Tuncer M. Effect of teeth clenching on handgrip force in adult men: role of periodontal mechanoreceptors. Acta Neurol Belg 2023; 123(5):1945-1956. https://doi.org/10.1007/s13760-023-02283-1.
Türkel I., Özerkliğ B.; Yılmaz M., Ülger Ö. Kubat GB., Tuncer M. Mitochondrial transplantation as a possible therapeutic option for sarcopenia. J Mol Med 2023 101(6): 645-669. https://doi.org/10.1007/s00109-023-02326-3.
Y Karasu, D Önal, S Zırh, N Yersal, H Korkmaz, Y Üstün, S Müftüoğlu, B Pehlivanoğlu. Role of telocytes in the pathogenesis of ectopic pregnancy. Eur Rev Med Pharmacol Sci. 2022; 26(1):110-119. doi: 10.26355/eurrev_202201_27754.
H. Korkmaz, A. Savrun, D. Önal, B. Pehlivanoğlu. Is the Relation between Waist Circumference and Anxiety Scores Gender Specific?Gazi Medical Journal 2022:33(3), 220-223. doi: 10.12996/gmj.2022.52.
M Demeli, S Bayrak, B. Pehlivanoğlu. Adenozinin Uyku-Uyanıklık Döngüsündeki Etkileri. Türk Uyku Tıbbı Dergisi 2022: 9 190-198. doi:10.4274/jtsm.galenos.2022.36349.
Kaya K, Gelir E, Karaismailoglu E, Karaismailoglu S. Disentangling the P300 Components of Evoked Potentials Elicited using Subliminal Oddball Tasks in Reward-Directed Motivation. Neurological Sciences and Neurophysiology 2022, 39(4):206-212. doi:10.4103/nsn.nsn_109_22.
Konar NM, Karaismailoglu S, Karaismailoglu E. Status and trends of personalized medicine research from 2000 to 2020: a bibliometric analysis. Curr Med Res Opin 2022, 38(5):837-846. doi: 10.1080/03007995.2022.2052515.
Kaya K, Zavriyev AI, Orihuela-Espina F, Simon MV, LaMuraglia GM, Pierce ET, Franceschini MA, Sunwoo J. Intraoperative Cerebral Hemodynamic Monitoring during Carotid Endarterectomy via Diffuse Correlation Spectroscopy and Near-Infrared Spectroscopy. Brain Sci. 2022 Aug 2;12(8):1025
Bayraktar UA, Arıhan O, Atalay Ö, Gök M, Çiçek Ç, Bodur E, Tuncer M. Melatonin is effective in attenuating cisplatin-induced neurotoxicity. J Biochem Mol Toxicol. 2022 Jul;36(7):e23075
Ozbilgic T, Suslu AE, Aykan HH, Pehlivanoglu B, Onal D, Kasikci M, Duzova A, Emiralioglu N, Yalcin EE, Ersoz DD, Kiper EN, Ozcelik HU. The impact of the Adenotonsillectomy on cardiac functions and oxidative stress. Int J Pediatr Otorhinolaryngol. 2022 Mar;154:111039. doi: 10.1016/j.ijporl.2021.111039
Konar NM, Karaismailoglu S, Karaismailoglu E. Status and trends of personalized medicine research from 2000 to 2020: a bibliometric analysis. Curr Med Res Opin. 2022 May;38(5):837-846. doi: 10.1080/03007995.2022.2052515.
Barış VÖ, Erdem A. Can ARNI Prevent Doxorubicin-Induced Cardiotoxicity? Anatol J Cardiol. 2022 Apr;26(4):342-343. doi: 10.5152/AnatolJCardiol.2021.1370
Kartal Y, Tokat UM, Kelicen-Ugur P, Yılmaz S, Karahan S, Budak MT. Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells. Curr Mol Pharmacol. 2022 May 10. doi: 10.2174/1874467215666220510112118
Barış VÖ, Dinçsoy AB, Gedikli E, Zırh S, Müftüoğlu S, Erdem A. Empagliflozin Significantly Prevents the Doxorubicin-induced Acute Cardiotoxicity via Non-antioxidant Pathways. Cardiovasc Toxicol. 2021 Sep;21(9):747-758. doi: 10.1007/s12012-021-09665-y.
Karaismailoglu E, Karaismailoglu S. Two novel nomograms for predicting the risk of hospitalization or mortality due to COVID-19 by the naïve Bayesian classifier method. J Med Virol. 2021 May;93(5):3194-3201. doi: 10.1002/jmv.26890
Arihan O, Nader E, Oto G, Kocak Y, Fort R, Connes P. Aqueous extract of chives (Allium schoenoprasum L.) plant impairs erythrocyte deformability in sickle cell patients. Clin Hemorheol Microcirc. 2021;79(2):357-361. doi: 10.3233/CH-201036
Barış VÖ, Dinçsoy B, Gedikli E, Erdemb A. Empagliflozin significantly attenuates sotalol-induced QTc prolongation in rats. Kardiol Pol. 2021 Jan 25;79(1):53-57. doi: 10.33963/KP.15666.
Tuncer M, Pehlivanoglu B, Sürücü SH, Isbir T. Melatonin Improves Reduced Activities of Membrane ATPases and Preserves Ultrastructure of Gray and White Matter in the Rat Brain Ischemia/Reperfusion Model. Biochemistry (Mosc). 2021 May;86(5):540-550. doi: 10.1134/S0006297921050035.
Oksuz E, Yasar S, Erten R, Arihan O, Oto G. Comparison of effects of high and low dose paracetamol treatment and toxicity on brain and liver in rats. North Clin Istanb. 2020 Nov 18;7(6):541-550. doi: 10.14744/nci.2020.54926
Arslanca T, Korkmaz H, Arslanca SB, Pehlivanoglu B, Celikel Ö. The Relationship between Vitamin D and Vasomotor Symptoms During the Postmenopausal Period. Clin Lab. 2020 Jul 1;66(7). doi: 10.7754/Clin.Lab.2019.191116
Acar I, Cetinkaya A, Lay I, Ileri-Gurel E. The role of calcium-sensing receptors in GLP-1 and PYY secretion after acute intraduodenal administration of L-tryptophan in rats. Nutr Neurosci. 2020 Jun;23(6):481-489.
Kubat GB, Ozler M, Ulger O, Ekinci O, Atalay O, Celik E, Safali M, Budak MT. The effects of mesenchymal stem cell mitochondrial transplantation on doxorubicin-mediated nephrotoxicity in rats. J Biochem Mol Toxicol. 2021 Jan;35(1):e22612. doi: 10.1002/jbt.22612
Kubat GB, Kartal Y, Atalay O, Ulger O, Ekinci O, Celik E, Safali M, Urkan M, Karahan S, Ozler M, Cicek Z, Budak MT. Investigation of the effect of isolated mitochondria transplantation on renal ischemia-reperfusion injury in rats. Toxicol Appl Pharmacol. 2021 Dec 15;433:115780. doi: 10.1016/j.taap.2021.115780
Kalyoncu Ş, Yilmaz B, Demİr M, Tuncer M, Bozdağ Z, Ince O, Bozdayi MA, Ulusal H, Taysi S. Melatonin attenuates ovarian ischemia reperfusion injury in rats by decreasing oxidative stress index and peroxynitrite. Turk J Med Sci. 2020 Oct 22;50(6):1513-1522 doi: 10.3906/sag-2004-135.
Demİr M, Yilmaz B, Kalyoncu Ş, Tuncer M, Bozdağ Z, Ince O, Bozdayi MA, Ulusal H, Taysi S. Metformin reduces ovarian ischemia-reperfusion injury in rats by improving oxidative/nitrosative stress. Taiwan J Obstet Gynecol. 2020 doi: 10.1016/j.tjog.2020.10.004 (in press)
Kalyoncu S, Yilmaz B, Demir M, Tuncer M, Bozdag Z, Ince O, Akif Bozdayi M, Ulusal H, Taysi S. Octreotide and lanreotide decrease ovarian ischemia–reperfusion injury in rats by improving oxidative and nitrosative stress. J Obstet Gynaecol Res. 2020 Oct;46(10):2050-2058. doi: 10.1111/jog.14379.
Korkmaz H, Önal D, Alışık M, Erel Ö, Pehlivanoğlu B. The impact of oxytocin on thiol/disulphide and malonyldialdehyde/glutathione homeostasis in stressed rats. Biol Chem. 2020 Oct 25;401(11):1283-1292. doi: 10.1515/hsz-2020-0190.
S Arisoy, O Sayiner, T Comoglu, D Onal, O Atalay, B Pehlivanoglu “In vitro and in vivo Evaluation of Levodopa-Loaded Nanoparticles for Nose to Brain Delivery” Pharm Dev Technol. 2020, 25(6) doi: 10.1080/10837450.2020.174025

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Research Infrastructure

Researchers

<ul> <li style="margin-bottom:11px">Prof. Dr. Bilge Pehlivanoğlu (Head of the Department)</li> <li style="margin-bottom:11px">Prof. Dr. Neslihan H. DİKMENOĞLU FALKMARKEN</li> <li style="margin-bottom:11px">Prof. Dr. Ayşen ERDEM</li> <li style="margin-bottom:11px">Prof. Dr. Meltem TUNCER</li> <li style="margin-bottom:11px">Doç. Dr. Esin İLERİ GÜREL</li> <li style="margin-bottom:11px">Doç. Dr. Okan ARIHAN</li> <li style="margin-bottom:11px">Doç. Dr. Hilal KORKMAZ</li> <li style="margin-bottom:11px">Dr. Öğr. Üyesi Serkan KARAİSMAİLOĞLU</li> <li style="margin-bottom:11px">Dr. Öğr. Üyesi Aslı Şan DAĞLI GÜL</li> <li style="margin-bottom:11px">Dr. Öğr. Üyesi Nazlı KARİMİ</li> <li style="margin-bottom:11px">Öğr. Gör. Dr. Ahmet Onur DAŞTAN</li> <li style="margin-bottom:11px">Öğr. Gör. Dr. Simay ALCAN</li> <li style="margin-bottom:11px">Öğr. Gör. Dr. Kamran HAGHIZADE</li> <li style="margin-bottom:11px">Uzm. Dr.  Mustafa GÖRMÜŞ</li> <li style="margin-bottom:11px">Arş. Gör. Dr. Özbeyen ATALAY</li> <li style="margin-bottom:11px">Arş. Gör. Dr. Kübra BULUT</li> <li style="margin-bottom:11px">Arş. Gör. Dr. Ayşe Kübra IŞIK</li> <li style="margin-bottom:11px">Arş. Gör. Esra Nur ALKAN</li> </ul>

Ongoing Projects

<ul> <li>The Relationship Between Functional and Structural Connectivity and GJA1 Gene Single Nucleotide Polymorphisms in Alzheimer's Patients- Prof. Dr. Bilge PEHLİVANOĞLU</li> <li>The Protective Effect of Dapagliflozin on Intestinal Ischemia-Reperfusion Injury- Assoc. Prof. Esin İLERİ GÜREL</li> <li>The Effect of Caffeine and Glucose Consumption on Prefrontal Cortex Activity and Cognitive Performance- Assist. Prof. Serkan KARAİSMAİLOĞLU</li> <li>The Measurement of CRP, IL-17, and IL-19 Levels in Serum and Saliva of Patients with Acne Vulgaris- Assist. Prof. Nazlı KARİMİ</li> </ul>

Completed Projects

<ul> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Antihypertensive Effect of Hesperidin and Aerobic Exercise in L-NAME Induced Hypertensive Rats - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Comparison of the Effects of Mitochondria Transplantation and Exercise in an Experimental Parkinson's Disease Model - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effects of Mitotempo on Trigeminal Ganglion Mitochondrial Dysfunction in an Experimental Migraine Model - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Hacettepe Solution on Ischemia Reperfusion Injury with an Extracorporeal Circulation System - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Recognizing Social Hierarchy in Schizophrenia - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Relationship Between Functional and Structural Connectivity and Gja1 Gene Single Nucleotide Polymorphisms in Alzheimer's Patients - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effects of Low and High Doses of Caffeine on Anxiety Created Using Virtual Reality - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Taurine on Tumor Size and Metastasis in Triple-Negative Breast Cancer Treated with Doxorubicin - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Protective Effect of Intermittent Fasting on Biochemical, Histopathological and Behavioral Parameters in Diabetic Rats Exposed to Acrylamide - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">High-Resolution Microscopic Examination of Deep Structures of Tissue and Live Animals Using Multiphoton Microscopy - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Anxiolytic Effect of Salvia heldreichiana (Footed Sage) in Single and Repeated Doses on Rats - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Platelet-Rich Fibrin on Colon Anastomosis - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Synergistic Effects of Stattic and Paclitaxel on Proliferation and Metastasis in Triple-Negative Breast Cancer - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Empagliflozin on Doxorubicin-Induced Cardiomyopathy in Rats - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Empagliflozin on Sotalol-Induced QT Prolongation - Prof. Dr. Ayşen Erdem</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Conducting "In Silico" Experiment Simulation in the Medical Faculty Physiology Student Laboratory - Prof. Dr. Ethem Gelir</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Optical Monitoring of Cerebral Blood Flow and Metabolism During Carotid Endarterectomy - Prof. Dr. Ethem Gelir</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Short- and Long-Acting Somatostatin Analogues, Octreotide and Lanreotide, in Protecting Ovarian Damage in a Rat Ischemia-Reperfusion Model - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Melatonin and Metformin in Protecting Ovarian Damage in a Rat Ischemia-Reperfusion Model - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effects of Melatonin on Membrane ATPase Activities and Ultrastructurally on White and Gray Matter in Forebrain Ischemia-Reperfusion Injury - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Demonstration of Transplacental Passage of Mitochondria Isolated from Rat Mesenchymal Stem Cells from Mother to Offspring - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Imaging of the Biodistribution of Mitochondria After Mitochondrial Transplantation - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effects and Signaling Pathways of Isolated Mitochondria Transplantation in a COVID-19-Like Acute Respiratory Distress Syndrome Model in Rats - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effects of Mitochondrial Transplantation and Exercise in an Experimental Skeletal Muscle Atrophy Model Induced by Doxorubicin - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Melatonin on Cisplatin-Induced Neurotoxicity in Rats - Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Preparation, Characterization, and In Vivo Evaluation of the Efficacy of Orally Disintegrating Mini Tablet Formulations Containing Atomoxetine Using Quality by Design (QbD) System in the Treatment of Attention Deficit and Hyperactivity Disorder - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Fospropofol on Vascular Smooth Muscle - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Sulodexide on Vascular Smooth Muscle - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Oxytocin on the Neural Response to Different Fearful Stimuli in Humans: The Role of Interpersonal Genetic Variations - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Body Weight on Motor Skills and Its Relationship with Central Dopamine and Dopamine Receptor Levels in a Rat Model of Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Role of the Complement System and Its Modulation by Catechin in the Neuroinflammation Process of Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effect of Myosin Light Chain Kinase Inhibitor ML7-Loaded Nanofiber Polymers on Myometrial Contraction - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">An Extracorporeal Circulation Model for Solving the Long Ischemia Problem During Transplantation and Replantation - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">In Vivo Investigation of the Efficacy of Different Combinations of Quercetin, Silibinin, and Epigallocatechin Gallate in the Treatment of 4T1 Breast Cancer - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Preparation, Characterization, and In Vivo Evaluation of the Efficacy of Brain-Targeted, Wheat Germ Agglutinin (WGA)-Conjugated PLGA Nanoparticles in Parkinson's Disease - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Evaluation of Systemic and Pulmonary Hypertension, Cardiac Functions, and the Factors Affecting Them in Pre- and Post-Adenoidectomy Periods in Children with Adenotonsillar Hypertrophy and Obstructive Sleep Apnea - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Oxytocin on the Neural Response to Different Fearful Stimuli in Humans: The Role of Interpersonal Genetic Variations - Prof. Dr. Bilge Pehlivanoğlu (Bu madde 29 ile aynıdır)</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Role of Telocyte Cells in the Fallopian Tube in the Pathogenesis of Ectopic Pregnancy - Prof. Dr. Bilge Pehlivanoğlu</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Extraocular Muscle Regeneration with Decellularized Bovine Extraocular Muscle and PCL-Muscle Matrix Composite Tissue Scaffolds - Prof. Dr. Ayşen Erdem, Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Evaluation of the Effect of a Biological Conduit Model for Peripheral Nerve Defect Repair: A Nerve Conduit Model Containing De-Epithelialized Human Amniotic Membrane and Adipose-Derived Mesenchymal Stem Cell Layer on Nerve Healing - Prof. Dr. Ayşen Erdem, Prof. Dr. Meltem Tuncer</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Agmatine and L-Arginine on GLP-1 and PYY Secretion in Human NCI-H716 Cells: The Role of Calcium-Sensing Receptors (CaSR) - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Relationship Between Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB), Blood Glucose Level, and Hepatic Steatosis - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Oral Caprylic Acid Administration on Acyl-Ghrelin and Growth Hormone Levels and Anxiety in Growing Rats - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Effect of Methylprednisolone on Gentamicin-Induced Nephrotoxicity in Rats - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Biodistribution, Histopathological and Biochemical Effects of Silver Nanoparticles Functionalized by Coating with Three Different Biocompatible Polysaccharide Nanocomposites in Mice - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of Serum Obestatin and Ghrelin Levels in Girls Followed Up with a Diagnosis of Central Precocious Puberty - Doç. Dr. Esin İleri Gürel</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effects of Subacute Carvacrol Administration on Behavioral and Oxidative Stress Parameters During NAF Exposure - Doç. Dr. Okan Arıhan</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Protective Effect of Carvacrol on Behavioral, Biochemical, and Metabolomic Parameters in Cadmium-Exposed Rats - Doç. Dr. Okan Arıhan</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Anxiolytic Effect of Cocoa (Theobroma cacao) Applied at Different Doses and with Sucrose on Rats - Doç. Dr. Okan Arıhan</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Isolated Mitochondria Transplantation on Renal Ischemia-Reperfusion Injury in Rats - Doç. Dr. Murat Timur Budak</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Aromatase/Sirtuin-1 Interaction on miRNA Expression Levels in Cell Culture - Doç. Dr. Murat Timur Budak</li> <li class="ds-markdown-paragraph" style="margin-top:7px">The Role of Changes in Respiratory Functions, Exercise Capacity, and Quality of Life in Patients with Primary Ciliary Dyskinesia in Oxidant and Antioxidant Response - Doç. Dr. Murat Timur Budak</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Effects of Silibinin on Langerhans Islets and Cognitive Functions in a Streptozotocin-Induced Rat Diabetes Model - Öğr. Gör. Dr. Aslı Şan Dağlı Gül</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Effect of Salvia aytachii (Moon-shaped Sage) on Blood Glucose Levels in Streptozotocin-Induced Diabetic Rats - Öğr. Gör. Dr. Aslı Şan Dağlı Gül</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Evaluation of the Effects of Different Cognitive Tasks on Sympathetic Responses: Implementation of a High-Precision, Low-Cost Complementary Method - Öğr. Gör. Dr. Nazlı Karimi</li> <li class="ds-markdown-paragraph" style="margin-top:7px">Investigation of the Expression Levels of Murf-1 and Atrogin-1 Genes and Redox Status in Atrophy Induced by Hydrogen Peroxide in Melatonin-Treated Mouse Myoblast Cell Line - Öğr. Gör. Dr. Nazlı Karimi</li> </ul>

Publications

<ul> <li style="text-align:justify">Savran OY, Tuncer M. “Possible role of novel mitochondrial subsets in migraine”. Life (Basel) 2025 15(8), 1273.</li> <li style="text-align:justify">Yülek F, Akdere ÖE, Akbayrak SK, Gümüşderelioğlu M, Çaylı S, Alimoğulları E, Erdem A, Tuncer M, Atalay Ö. “Engineered Extraocular Muscle with Decellularized Tissue and Synthetic Biodegradable Polymers: Design, Properties, and In Vivo Studies” ACS Biomater Sci Eng 2025 SEP 8; 11(9):5482-5497.</li> <li style="text-align:justify">Pehlivanoğlu B, Tuncer M, Doğan M. “Metformin Attenuates Spontaneous and Stimulated Myometrium Contractions in Rat Uterine Strips” Eurasian J Med 2025 57(3): 1-6.</li> <li style="text-align:justify">Y. Karasu, M. Demeli Ertuş, D. Önal, B. Topçu, H. Eroğlu, B. Pehlivanoğlu. In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7. Eur Rev Med Pharmacol Sci 2024; 28 (5): 1891-1903. doi: 10.26355/eurrev_202403_35603.</li> <li style="text-align:justify">Yildiz Y, Mutlu E, Arihan O, Yagcioglu AEA, Dikmenoglu Falkmarken NH. Investigation of hemorheological parameters in patients with major depressive disorder.  Clin Hemorheol Microcirc. 2024;87(3):333-345. doi: 10.3233/CH-232061.</li> <li style="text-align:justify">D. Önal, H. Korkmaz, G. Önal, B. Pehlivanoğlu. Body weight modulates the impact of oxytocin on chronic cold-immobilization stress response. Peptides 2024; 30;177:171202. doi: 10.1016/j.peptides.2024.171202.</li> <li style="text-align:justify">Korkmaz H, Pehlivanoğlu B. Is Vitamin D a Crucial Molecule for Musculoskeletal and Cardiovascular Systems in Postmenopausal Women? Front Biosci (Landmark Ed). 2024; 29(8): 281. doi: 10.31083/j.fbl2908281.</li> <li style="text-align:justify">Ö Atalay., ED Ozyilmaz, D Önal, D, B Pehlivanoğlu, TÇomoğlu. Development and In vivo Evaluation of Atomoxetine Hydrochloride ODMTs in a Nicotine-Induced Attention Deficit Hyperactivity Disorder (ADHD) Model in Rats. AAPS PharmSciTech 2024; 25, 173. https://doi.org/10.1208/s12249-024-02889-5.</li> <li style="text-align:justify">Ors Yildirim N, Yildirim AK, Demeli Ertus M, Dastan AO, Pehlivanoglu B, Chi YW, Gianesini S, Doganci S, Yildirim V. Sulodexide Inhibits Arterial Contraction via the Endothelium-Dependent Nitric Oxide Pathway. J Clin Med. 2024; 13(8): 2332. doi: 10.3390/jcm13082332</li> <li style="text-align:justify">Kubat GB, Tuncer M. Doxorubicin-dependent skeletal muscle atrophy: Exercise and mitochondrial dysfunction. Turkish Journal of Sports Medicine 2024 59(1): 39-43.</li> <li style="text-align:justify">Kubat GB, Ulger O, Atalay O, Fatsa T, Turkel I, Ozerklig B, Celik E, Ozenc E, Simsek G, Tuncer M. The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy. Journal of Muscle Research and Cell Motility 2024 45:233–251. https://doi.org/10.1007/s10974-024-09676-6.          </li> <li style="text-align:justify">H Korkmaz, CD Deveci, Y Üstün, B Pehlivanoğlu. Comparison of plasma oxytocin level in women with natural and surgical menopause. Endocrine 2023;82(1):209-214. doi: 10.1007/s12020-023-03453-0.</li> <li style="text-align:justify">Kartal Y, Tokat UM, Kelicen-Ugur P, Yılmaz S, Karahan S, Budak MT. Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells. Curr Mol Pharmacol. 2023;16(6):609-628. doi: 10.2174/1874467215666220510112118.</li> <li style="text-align:justify">M Doğan, AM Sevgili, İ Kozanoğlu, B Pehlivanoğlu. Effect of acute or subchronic stress on T cell response in peripheral blood: Regulatory role of vitamin D. In J Exper Biol. 2023; 61. 14-24. doi: 10.56042/ijeb.v61i01.60922.</li> <li style="text-align:justify">S Doğancı, ME İnce, M Demeli, N Örs-Yıldırım, B Pehlivanoğlu, AK Yıldırım, S Gianesini, YW Chi, V Yıldırım. Sulodexide Develops Contraction in Human Saphenous Vein via Endothelium-Dependent Nitric Oxide Pathway. J. Clin. Med. 2023, 12, 1019. https://doi.org/10.3390/jcm1203101.</li> <li style="text-align:justify">Kubat, GB, Bouhamida, E, Ulger O, Turkel I, Pedriali G, Ramaccini D, Ekinci O, Ozerklig B, Atalay O, Patergnani S, Sahin BN, Morciano G, Tuncer M, Tremoli E, Pinton P. Mitochondrial Dysfunction and Skeletal Muscle Atrophy: Causes, Mechanisms, and Treatment Strategies. Mitochondrion 2023; 72:33-58. https://doi.org/10.1016/j.mito.2023.07.003</li> <li style="text-align:justify">Tuncer M, Alcan S. Pyroptosis: a new therapeutic strategy in cancer. Mol Biol Rep 2023 50(7):6191-6200. https://doi.org/10.1007/s11033-023-08482-6.</li> <li style="text-align:justify">Yılmaz MM, Akdere ÖE, Gümüşderelioğlu M, Bayrak GK, Koç S, Erdem A, Tuncer M, Atalay Ö, Kaplanoğlu GK, Akarca Dizakar SÖ, Calis M. Biological nerve conduit model with de-epithelialized human amniotic membrane and adipose-derived mesenchymal stem cell sheet for repair of peripheral nerve defects. Cell Tissue Res 2023; 391(3):505-522. https://doi.org/10.1007/s00441-022-03732-8.</li> <li style="text-align:justify">Kayabekir M, Tuncer M. Effect of teeth clenching on handgrip force in adult men: role of periodontal mechanoreceptors. Acta Neurol Belg 2023; 123(5):1945-1956. https://doi.org/10.1007/s13760-023-02283-1.</li> <li style="text-align:justify">Türkel I., Özerkliğ B.; Yılmaz M., Ülger Ö. Kubat GB., Tuncer M. Mitochondrial transplantation as a possible therapeutic option for sarcopenia. J Mol Med 2023 101(6): 645-669. https://doi.org/10.1007/s00109-023-02326-3.</li> <li style="text-align:justify">Y Karasu, D Önal, S Zırh, N Yersal, H Korkmaz, Y Üstün, S Müftüoğlu, B Pehlivanoğlu. Role of telocytes in the pathogenesis of ectopic pregnancy. Eur Rev Med Pharmacol Sci. 2022; 26(1):110-119. doi: 10.26355/eurrev_202201_27754.</li> <li style="text-align:justify">H. Korkmaz, A. Savrun, D. Önal, B. Pehlivanoğlu. Is the Relation between Waist Circumference and Anxiety Scores Gender Specific?Gazi Medical Journal 2022:33(3), 220-223. doi: 10.12996/gmj.2022.52.</li> <li style="text-align:justify">M Demeli, S Bayrak, B. Pehlivanoğlu. Adenozinin Uyku-Uyanıklık Döngüsündeki Etkileri. Türk Uyku Tıbbı Dergisi 2022: 9 190-198. doi:10.4274/jtsm.galenos.2022.36349.</li> <li style="text-align:justify">Kaya K, Gelir E, Karaismailoglu E, Karaismailoglu S. Disentangling the P300 Components of Evoked Potentials Elicited using Subliminal Oddball Tasks in Reward-Directed Motivation. Neurological Sciences and Neurophysiology 2022, 39(4):206-212. doi:10.4103/nsn.nsn_109_22.</li> <li style="text-align:justify">Konar NM, Karaismailoglu S, Karaismailoglu E. Status and trends of personalized medicine research from 2000 to 2020: a bibliometric analysis. Curr Med Res Opin 2022, 38(5):837-846. doi: 10.1080/03007995.2022.2052515.</li> <li style="text-align:justify">Kaya K, Zavriyev AI, Orihuela-Espina F, Simon MV, LaMuraglia GM, Pierce ET, Franceschini MA, Sunwoo J. Intraoperative Cerebral Hemodynamic Monitoring during Carotid Endarterectomy via Diffuse Correlation Spectroscopy and Near-Infrared Spectroscopy. Brain Sci. 2022 Aug 2;12(8):1025</li> <li style="text-align:justify">Bayraktar UA, Arıhan O, Atalay Ö, Gök M, Çiçek Ç, Bodur E, Tuncer M. Melatonin is effective in attenuating cisplatin-induced neurotoxicity. J Biochem Mol Toxicol. 2022 Jul;36(7):e23075</li> <li style="text-align:justify">Ozbilgic T, Suslu AE, Aykan HH, Pehlivanoglu B, Onal D, Kasikci M, Duzova A, Emiralioglu N, Yalcin EE, Ersoz DD, Kiper EN, Ozcelik HU. The impact of the Adenotonsillectomy on cardiac functions and oxidative stress. Int J Pediatr Otorhinolaryngol. 2022 Mar;154:111039. doi: 10.1016/j.ijporl.2021.111039</li> <li style="text-align:justify">Konar NM, Karaismailoglu S, Karaismailoglu E. Status and trends of personalized medicine research from 2000 to 2020: a bibliometric analysis. Curr Med Res Opin. 2022 May;38(5):837-846. doi: 10.1080/03007995.2022.2052515.</li> <li style="text-align:justify">Barış VÖ, Erdem A. Can ARNI Prevent Doxorubicin-Induced Cardiotoxicity? Anatol J Cardiol. 2022 Apr;26(4):342-343. doi: 10.5152/AnatolJCardiol.2021.1370</li> <li style="text-align:justify">Kartal Y, Tokat UM, Kelicen-Ugur P, Yılmaz S, Karahan S, Budak MT. Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells. Curr Mol Pharmacol. 2022 May 10. doi: 10.2174/1874467215666220510112118</li> <li style="text-align:justify">Barış VÖ, Dinçsoy AB, Gedikli E, Zırh S, Müftüoğlu S, Erdem A. Empagliflozin Significantly Prevents the Doxorubicin-induced Acute Cardiotoxicity via Non-antioxidant Pathways. Cardiovasc Toxicol. 2021 Sep;21(9):747-758. doi: 10.1007/s12012-021-09665-y.</li> <li style="text-align:justify">Karaismailoglu E, Karaismailoglu S. Two novel nomograms for predicting the risk of hospitalization or mortality due to COVID-19 by the naïve Bayesian classifier method. J Med Virol. 2021 May;93(5):3194-3201. doi: 10.1002/jmv.26890</li> <li style="text-align:justify">Arihan O, Nader E, Oto G, Kocak Y, Fort R, Connes P. Aqueous extract of chives (Allium schoenoprasum L.) plant impairs erythrocyte deformability in sickle cell patients. Clin Hemorheol Microcirc. 2021;79(2):357-361. doi: 10.3233/CH-201036</li> <li style="text-align:justify">Barış VÖ, Dinçsoy B, Gedikli E, Erdemb A. Empagliflozin significantly attenuates sotalol-induced QTc prolongation in rats. Kardiol Pol. 2021 Jan 25;79(1):53-57. doi: 10.33963/KP.15666.</li> <li style="text-align:justify">Tuncer M, Pehlivanoglu B, Sürücü SH, Isbir T. Melatonin Improves Reduced Activities of Membrane ATPases and Preserves Ultrastructure of Gray and White Matter in the Rat Brain Ischemia/Reperfusion Model. Biochemistry (Mosc). 2021 May;86(5):540-550. doi: 10.1134/S0006297921050035.</li> <li style="text-align:justify">Oksuz E, Yasar S, Erten R, Arihan O, Oto G. Comparison of effects of high and low dose paracetamol treatment and toxicity on brain and liver in rats. North Clin Istanb. 2020 Nov 18;7(6):541-550. doi: 10.14744/nci.2020.54926</li> <li style="text-align:justify">Arslanca T, Korkmaz H, Arslanca SB, Pehlivanoglu B, Celikel Ö. 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