In the laboratory units of the center, which has a multi-disciplinary structure, researches are carried out in the fields of stem cell, gene therapies, cellular therapies, tissue engineering and regenerative medicine in the presence of experienced researchers.
• Laminar Flow Cabins
• Thermo Hera safe class 2 cabin
• Metisafe Class 2 cabin
• Thermo Hera safe Class 2 cabin
• Thermo Hera Safe KS Class 2 cabin
• Biolab BH-EN2004
• Metisafe Class 2 cabin
• Thermo Hera Safe Class 2 cabin
• Centrifuges
• Eppendorf 5804
• Eppendorf 5804
• Eppendorf 5810 R
• Core NF800 R
• Eppendorf 5810 R
• Becman Coulter Microfuge 16
• Eppendorf 5810 R
• Eppendorf 5810
• Coolers:
• Arçelik (-20 C0) / Deep Freezer
• Arçelik (+4) / Refrigerator
• Sanyo (-20 C0) / Deep Freezer
• Vestel (+4) / Mini Refrigerator
• Panosonic (-) 40
• NÜVE DF590 (-) 80
• New Brunswick u410 (-) 80
• SANYO (-) 20
• SANYO (-) 80
• Rsbiotech Eclipse 400 (-80)
• Incubators
• Thermo Heracell150
• Eppendorf New Brunswick S41i
• Core EC160
• Core EC160
• Core EN120
• Core EC160
• New Brunswick GALAXY 170 R
• Panasonic
• Thermo Heracell150
• Microscopes
• LEICA DME
• OLYMPUS CX31
• OLYMPUS CKX41
• LEICA DM500
• OLYMPUS IX73
• OLYMPUS DP71 CKX41
• OLYMPUS DP71 CKX41
• LEICA DMI6000B
• OLYMPUS CKX41
• EVOS
• PCR Instruments
• EPPENDORF THERMAL CYCLER PCR DEVICE
• AB APPLIED BIOSTEM / GENE AMP 9700
• BioRAD T100
• Roche 480 Real-time PCR instrument
• Nitrogen Tanks
• CHART / LIQUID NITROGEN STORAGE CONTAINER
• CHART U EUROCYL 180/4 / NITROGEN CARRYING TANK
• CHART U EUROCYL 230 / 7.0 / NITROGEN CARRYING TANK
• CHART U EUROCYL 230 / 7.0 / NITROGEN CARRYING TANK
• CHART U EUROCYL 230 / 7.0 / NITROGEN CARRYING TANK
• CHART U EUROCYL 230 / 7.0 / NITROGEN CARRYING TANK
• CHART MVE 810 / LIQUID NITROGEN STORAGE CONTAINER
• STATE BOURNE / LIQUID NITROGEN STORAGE CONTAINER
• Other Devices
• GFL-1086 Water Bath
• WISESTIR MSH-20A Magnetic stirrer
• BioRad Transblot Western transfer system
• WISESTIR MSH-20A Magnetic stirrer
• NAHİTA 681/5 CODE: 50681500
• Mettler Toledo pH Meter
• Wisd Magnetic stirrer
• GFL / 3005 mixer
• APOLLO DIGITAL DRY HEATER-T
• Mise-stir MSH-20A Magnetic stirrer
• NANODROP
• CASY SCREEN AND INNOVATIS MAIN BODY
• Lonza Lucetta Luminometer
• BIO-RAD TRANS-BLOT TURBO TRANSFER SYSTEM
• FLUOCHEM FC3 gel imaging
• TECAN SUNRİSE Elisa reader
• NÜVE ST402 bath
• MİLLİPORE vacuum pump
• BD FACS ARIA 1 (15 years old device out of use. Maintenance and repair required.)
• BD Accuri C6 Plus
• Prof. Dr. Duygu ÇETİNKAYA - Pediatric Hematology, Stem Cell Sciences; Director of Stem Cell AU Center
• Prof. Dr. AYŞEN GÜNEL ÖZCAN- Stem Cell Sciences (President of the USA),
• Associate Professor. Fatma Visal OKUR- Pediatric Hematology, Stem Cell Sciences, Stem Cell AU Center Director Asst.
• Associate Professor. Betül ÇELEBİ SALTIK- Stem Cell Sciences
• Asst.Prof. Fatima AERTS KAYA- Stem Cell Sciences
• Assistant Professor Neşe ÜNVER- Pediatric Pathology, Stem Cell Sciences
• Lecturer Dr. Cansu ÖZDEMİR SAKA- Stem Cell AU Center
• Lecturer Dr. Burcu ÖZÇİMEN- Stem Cell Sciences, Stem Cell AU Center
• Lecturer Dr. Özge Burcu ŞAHAN- Stem Cell Sciences, Stem Cell AU Center
• Lecturer Dr. Esin ALPDÜNDAR BULUT- Pediatric Hematology; Stem Cell AU Center
• Lecturer. İrem AKAR- Basic Oncology, Stem Cell AU Center
• Associate Professor. Basri GÜLBAKAN- Pediatric Metabolism, Stem Cell Sciences
• Prof. Dr. Barış KUŞKONMAZ- Pediatric Hematology
• Prof. Dr. Şule ÜNAL- Pediatric Hematology
• Asst.Prof. Tekin AKSU- Pediatric Hematology
• Assoc. Dr. Ebru CAN KURT- Neurology
• Prof. Dr. Emirhan NEMUTLU-Analytical Chemistry (Pharm.)
• Prof. Dr. Petek KORKUSUZ- Histology-Embryology, Stem Cell Sciences
• Prof. Dr. Nuhan PURALI- Biophysics, Stem Cell AU Center
• Prof. Dr. Türkan ELDEM- Pharmaceutical Biotechnology, Stem Cell Sciences, Stem Cell AU Center
• Assoc. Dr. Dilara ZEYBEK- Histology-Embryology, Stem Cell Sciences
• Associate Professor. Ayça ARSLAN ERGÜL-Bilkent UNAM, Stem Cell AU Center
• Prof. Dr. İbrahim VARGEL- Plastic Surgery; Stem Cell Sciences
• Prof. Dr. Çetin KOCAEFE- Medical Biology, Stem Cell Sciences, Deputy Director of Stem Cell AU Center
• Prof. Dr. Banu ANLAR- Ped.Neurology, Stem Cell Sciences
• Prof. Dr. Köksal ÖZGÜL- Ped. Metabolism, Stem Cell Sciences
• Prof. Dr. Günay BALTA- Ped. Hematology, Stem Cell Sciences
• Prof. Dr. Fatih ÖZALTIN- Ped. Nephrology
• Prof. Dr. YASEMİN BALABAN- Gastroenterology
• Associate Professor. Ekim TAŞKIRAN- Medical Genetics, Stem Cell Sciences
• Prof. Dr. Aylin GÜRPINAR- Department of Biology General Biology
• Asst.Prof. Handan SEVİM- Department of Biology General Biology
• Asst.Prof. Parisa SHARAFİ-TOBB Medical Biology
• Lecturer See. Dr. Ayşegül MENDİ- Gazi Uni. Dentist. Medical Microbiology
• Lecturer See. Dr. Suray PEHLİVANOĞLU- Stem Cell AU Center
Students
• ESRA KOÇAK- Stem Cell Sciences, Stem Cell AU Center
• GÜLSENA TONYALI- Stem Cell Sciences, Stem Cell AU Center
• MERİÇ BİLGİÇ KÜÇÜKGÜVEN- Stem Cell Sciences, Stem Cell AU Center
• MUSTAFA KELEŞ- Stem Cell Sciences, Stem Cell AU Center
• AYŞENUR GÖK- Stem Cell Sciences, Stem Cell AU Center
• ÖZLEM ALTUNDAĞ- Stem Cell Sciences, Stem Cell AU Center
• ÖZGÜR DOĞUŞ EROL- Stem Cell Sciences, Stem Cell AU Center
• OKAN AKÇA- Stem Cell Sciences, Stem Cell AU Center
• RUMEYSA TUNCER- Stem Cell Sciences, Stem Cell AU Center
• MELİS BASIC- Stem Cell Sciences, Stem Cell AU Center
• MEHMET EMİN ŞEKER- Stem Cell Sciences, Stem Cell AU Center
• İREM AKAR- Stem Cell Sciences, Stem Cell AU Center
• ÖZGE BURCU ŞAHAN- Stem Cell Sciences, Stem Cell AU Center
• BİHTER MURATOĞLU- Stem Cell Sciences, Stem Cell AU Center
• CEREN YILMAZ- Stem Cell Sciences, Stem Cell AU Center
• BURCU PERVİN- Stem Cell Sciences, Stem Cell AU Center
• KEMAL KAYAŞLI- Stem Cell Sciences, Stem Cell AU Center
• Graduate Students (Last 5 Years)
• Sevil KÖSE- Stem Cell Sciences, Stem Cell AU Center
• Cansu ÖZDEMİR SAKA- Stem Cell Sciences, Stem Cell AU Center
• Ilgın ÇAĞNAN- Stem Cell Sciences, Stem Cell AU Center
• Beyza GÖKÇINAR YAĞCI- Stem Cell Sciences, Stem Cell AU Center
• Yağız ANASIZ- Stem Cell Sciences, Stem Cell AU Center
• Selda AYHAN- Stem Cell Sciences, Stem Cell AU Center
• Beren KARAOSMANOĞLU- Stem Cell Sciences, Stem Cell AU Center
• Gözde AYDIN- Stem Cell Sciences, Stem Cell AU Center
• Tülay KARAAĞAÇ AKYOL- Stem Cell Sciences, Stem Cell AU Center
• Sema AYGAR- Stem Cell Sciences, Stem Cell AU Center
• Gülen ESKEN- Stem Cell Sciences, Stem Cell AU Center
• İnci CEVHER ZEYTİN- Stem Cell Sciences, Stem Cell AU Center
• Gülsena TONYALI- Stem Cell Sciences, Stem Cell AU Center
• Selin ÖNEN- Stem Cell Sciences, Stem Cell AU Center
• Neslihan DÖNMEZ- Stem Cell Sciences, Stem Cell AU Center
• Nur Kübra ÇANKIRILI- Stem Cell Sciences, Stem Cell AU Center
• Aynura MAMMADOVA- Stem Cell Sciences, Stem Cell AU Center
• Dilara DALKIRAN- Stem Cell Sciences, Stem Cell AU Center
• Eylem BAYSAL- Stem Cell Sciences, Stem Cell AU Center
• Berna ALKAN-Stem Cell Sciences, Stem Cell AU Center
• Zübeyde Çağla Köprü- H.Ü Nanotechnology
• Emine KILIÇ- Kırıkkale Uni. Faculty of Science. Histology
• Zeynep ÇOŞKUN- Gazi University. Immunology
• Hakan ÖZDOĞAN- Ankara University. Biotechnology
• Aysun SARIKAYA- Sakarya Uni. Department of Biology, METU Biology,
• Barış ULUM- METU Biology, Stem Cell AU Center
• Taner TEKER- METU Biology, Stem Cell AU Center
• TÜBİTAK STAR Scholars and Other Students
• CEREN MUŞERREF ŞELTE- TÜBİTAK STAR Scholarship, METU Biology, 2nd year January 2021- June 2021
• NİLAY ÇOLAK- TÜBİTAK STAR Scholarship holder, HACETTEPE Biology, 2nd Class. March 2021-August 2021
• SEMANUR GÜR-TÜBİTAK STAR Scholarship holder HACETTEPE Biology 4th Class. December 2020- June 2021
• BUSE NURTEN ÖZEL- Cambridge University, Department of Obstetrics and Gynecology Doctorate student
• WIDENING_TÜBITAK UIDB: 1071. Horizon 2020. EU Joint Program JPND Neurodegenerative Disease Research JPND / 120N123. 2020 - 2023. Humanized high-throughput co-culture system for motor neuron diseases. Obtaining and Detailed Characterization of Induced Pluripotent Stem Cell for Creating a High Capacity Co-Culture System in Motor Neuron Diseases. Director: D. Uçkan Çetinkaya. Stem Cell AU Center.
• 219S675 TÜBİTAK 1001, 15/06/20 Genetic Modification of Griscelli Syndrome Induced Pluripotent Stem Cells and Development of Gene Therapy. Director: F. Aerts-Kaya. Stem Cell Sciences; Stem Cell AU Center.
• -HÜ-BAP-THD-2019-18451 (06.12.2019-). "Investigation of P65 and PKNOX2 Interactions in Mesenchymal Stem Cell Aging". Coordinator: A. Günel-Özcan. Stem Cell Sciences ;, Stem Cell AU Center.
• TÜBİTAK 1001 Program, SBAG - Health Sciences Research Support Group, ARDEB. Project No: 117S275, Discovery of New Aptamer Based Surface Markers in Acute Myeloblastic Leukemia (AML) Disease, Researcher, 15.03.2018 - 15.01.2021 (Ongoing). Coordinator: Coordinator: B. Gülbakan. Pad. Metabolism; Stem Cell AU Center.
• TUK-2019-17760 HÜ-BAP, 26/04/19 Preparation of CRISPR / Cas9 and lentiviral constructs for Griscelli Syndrome genetic modification. Director: F. Aerts-Kaya Stem Cell Sciences; Stem Cell AU Center.
• 318S073 TÜBİTAK 1002, 01/09/19 Investigation of the Role of Neuropeptide Y (NPY) in Hematopoietic Stem Cell Regulation. Director: F. Aerts-Kaya. Stem Cell Sciences; Stem Cell AU Center.
• TPHD (Ped Hem Association) 2020-. The role of T and NK cell functions and biomarkers in the diagnosis of primary and secondary hemophagocytic lymphohistiocytosis. Coordinator: T. Aksu. Pediatric Hematology; Stem Cell AU Center.
• TÜBİTAK 1001: Demonstration of Immune Modulatory Effect of Mesenchymal Stem Cells in Hemophagocytic Syndrome Patient Samples. Director: H. Sevim. Biology; Stem Cell AU Center.
• 220S338 TÜBİTAK 1002, 01/11/20 Hematopoietic Stem Cell gene therapy culture conditions and engraftment optimization. Director: F. Aerts-Kaya. Stem Cell Sciences; Stem Cell AU Center.
• Hacettepe University Scientific Research Unit Project THD-2019-18322 (2019-) Executive Methionine Metabolism in Human Fetal Adult and Cancer Stem Cells. Executive B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU Center.
• Hacettepe University Scientific Research Unit Project THD-2019-18405 (2019-) Investigation of the Effect of Executive Oleuropein on Breast Cancer Organoid Culture in Microfluidic System. Executive B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU Center.
• Hacettepe University Scientific Research Unit Project TYL-2020-18963 (2020-) Executive Evaluation of the Effects of Exosomes and Bacteria Isolated from Saliva Samples of Patients with Head and Neck Cancer on Healthy Bone Marrow Mesenchymal Stem Cells. Executive B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU Center.
• EU ERA-NET / TÜBİTAK 120N645. New Approaches to the Treatment of Rare Kidney Disease C3 Glomerulopathy. Coordinator: F. Özaltın. Pad. Nephrology; Stem Cell AU center.
• TÜBİTAK 1003 / Development of induced pluripotent stem cell technologies (UPKH Bank Prototype) 2014-2019. Coordinator: D.Uçkan Çetinkaya. Stem Cell AU Center.
• EU-FP7 HEALTH-2010-261387-CELL-PID, 2010-2016 (01/11/2010 - 30/04/2016) Advanced cell- Therapies for the treatment of Primary ImmunoDeficiency. Large Scale Integrated Project. 2010-2017 Executive. D. Uçkan-Çetinkaya. Stem Cell AU Center.
FP7 - European Union Project -COST ActioN, HOX / TALE Expression Profiles in Mesenchymal Stem Cells of Fanconi Aplastic Anemia and Whole Genome miRNA Microarray Expressions2010-2017. Coordinator: A.Günel-Özcan. Stem Cell AU Center
• E-Rare JTC2015. European Diamond-Blackfan Anemia Consortium (EuroDBA). 2016- 2019. Coordinator: Ş, Ünal. Ped.Hematology; Stem Cell AU Center
• TÜBİTAK 1001: Project No: 117S145, SBAG. 15/03/18 - 15/03/20 Modeling of Osteoclast Defect with Infantile Osteopetrosis Patient with Induced Pluripotent Stem Cells, Osteoclast and Hematopoietic Niche Relationship. 2018-2020. Reads F.Visal. Stem Cell AU Center.
• TÜBİTAK 1001. Fanconi Anemia HOX and TALE Transcription Factors in Bone Marrow Mesenchymal Stem Cells: Gene Expressions and Protein Interactions. 2015-2017. Executive. A.Günel-Özcan. Stem Cell Sciences; Stem Cell AU Center.
• TÜBİTAK 1001. 113S819. 15/04/14 - 15/10/15 Investigation of the Presence and Level of Endocannabinoids and Receptors in Human Hematopoietic Stem Cells and Bone Marrow-Originated Mesenchymal Stem Cells. 2014-2016. Executive: P. Fearless. Histology / Embsriology / Stem Cell AU Center
• TÜBİTAK 1001. Hematopoietic Niche Characterization In Human Bone Marrow With Metabolome And Transcriptome Profiling. 2014-2016. Coordinator: K. Özgül. Pad. Metabolism. Stem Cell AU center.
• TÜBİTAK 1001. Mesenchymal Stem Cell Application in Children with Malignant Infantile Osteopetrosis. 2013-2015. Executive: B.Tavil. Pad. Hematology; Stem Cell AU center.
• TÜBİTAK 1001. Characterization of Bone Marrow Mesenchymal Stem Cells (Mkh) in Myelodysplastic Syndrome (Mds) and Acute Myeloid Leukemia (Aml) Patients and a Comparative Analysis of Gene / Micro RNA (miRNA) Expression Profiles with Healthy Controls. 2012-2015. Coordinator: O. İlhan. Ankara Univ. Hematology; Stem Cell AU center
• TÜBİTAK 1002. Characterization of Human Bone Marrow Hematopoietic Stem / Precursor Cells by Metabolic Analysis. 2018-2019. Coordinator: D.Uçkan-Çetinkaya. Stem Cell AU Center
• Tübitak 1002 Characterization of Stromal Cell Population in Skeletal Muscle Tissue. 01.08.2015-01.08.2016. Prof. Dr. Çetin KOCAEFE Executive Medical Biology, Stem Cell AU center.
• TÜBİTAK 1002 / 114S057: Investigation of the Immune Modulator Effect of Mesenchymal Stem Cells in an In Vitro Model to Form a Basis for Hemophagocytic Syndrome Clinical Applications. 2014-2015. Coordinator: A.Gürpınar. Biology; Stem Cell AU center.
• TÜBİTAK 1001. Interactions Between Human Bone Marrow Mesenchymal Stem / Stromal Cells (Mkh / Msh) And Plasticity Of Human Blood-Derived Macrophages. 2015-2019. Executive: V. Cloud. Gazi Univ. Immunology; Stem Cell AU Center.
• TÜBİTAK 1001. The Potential of Using Boron Compounds and Boron Coated Titanium Alloys as Biomaterials in Dentistry Concluded. 2015-2018. Director: A. Ugur. Gazi Dentist. Microbiology; Stem Cell AU Center.
• TUBITAK 1001-214Z033 (01.05.2015 - 01.11.2017). "HOX and TALE Transcription Factors in Fanconi Anemia Bone Marrow Mesenchymal Stem Cells: Gene Expressions and Protein Interactions". Executive. A.Günel-Özcan. Stem Cell Sciences; Stem Cell AU center.
• TUBİTAK ARDEB 1000-115R183 (01.07.2016 - 01.01.2017). Hacettepe University Regenerative and Restorative Medicine R&D Strategy Document. Executive. İ.Vargel. Plastic surgery; Stem Cell AU Center.
• TUBİTAK 3501 113S815 (2014-2017) Vascular Tissue Engineering with Bioreactor: Vascular Layer Formation with Umbilical Cord Stem Cells and Matrix Proteins. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• BAP Hacettepe: Investigation of the Effect of THD-2019-17607 Topoisomerase 2 inhibitor Etoposide on Dicer Expression of Stromal Cells. December 2018- December 2019. Supervisor: C.Özdemir-Saka. Stem Cell AU Center
• Stem cell recovery from Tübitak 1001 Zebrafish brain. 2014-2018. Coordinator Assoc. Ayça ARSLAN ERGÜL Stem Cell AU Center
• HÜ-BAP THD-2015-6461 (2015-2015) Recovery of CD146 + Cells from Human Umbilical Cord Vein and Differentiation into Vascular Smooth Muscle Cells. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• TÜBITAK-TEYDEP. Development of a kit “Point-of-Care” for the pre-diagnosis of acute leukemia. 2014-2016. Coordinator: Hemosoft Ltd. HU Technopolis; Stem Cell AU Center.
• 2015/03 Turkish Society of Hematology 15/10/15 - 15/12/16 Investigation of the role of chemicals that induce and reduce endoplasmic reticulum (ER) stress in the proliferation and differentiation capacity of Mesenchymal Stem Cells. Coordinator: D.Uçkan Çetinkaya. Stem Cell AU Center.
• TÜBİTAK 3001. Project No: 114S237. Synergistic Effect of Mesenchymal Stem Cells and Defibrotid in Arterial Thrombosis Model in Rats. 2014-2015. Director: D. Dilli. SamiUlus Children's Hospital; Stem Cell AU Center ..
• TÜBİTAK 1002. Determination of Bone Marrow and Tissue-Originating Mesenchymal Stem Cells in Neurofibromatosis1 (NF) Patients. 2014-2015. Coordinator: Banu Anlar. Ped.neurology. Stem Cell AU Center.
• 214S071 TÜBİTAK 1001, 15/04/2015 - 12/04/2019 Griscelli Syndrome UPKH (Induced Pluripotent Stem Cell) development, characterization and lymphohematopoietic differentiation Executive. F.Aerts-Kaya. Stem Cell Sciences; Stem Cell AU center.
• TUBİTAK 1002 113S717 (2014-2015) The Role of Pericytes and Mesenchymal Stem Cell Derived Osteoblasts in Umbilical Cord Hematopoietic Stem Cell Differentiation. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• 118S738 TÜBİTAK 1002, 15/09/18 - 15/09/19 Investigation of the Optimization of Hematopoietic Stem Cells for Hypothermic Storage Conditions. Executive. F.Aerts-rock. Stem Cell Sciences; Stem Cell AU center.
• Hacettepe University Scientific Research Unit Project THD-2016-10504 (2016-2017) Characterization of Smooth Muscle Cells Differentiated from Human Umbilical Cord Vein CD146 + Cells and Their Interactions with Extracellular Matrix Proteins. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• 2017/2 TÜBİTAK BİDEB 2221, guest scientist support. 15/01/18 - 15/01/19 Development of hematopoietic stem cell gene therapy for inherited diseases. Coordinator F. Aerts-Kaya. Stem Cell Sciences. Stem Cell AU center.
• METU-BAP, 31/12 / 16-31 / 12/17 Investigation of the Role of Neuropeptide Y (NPY) in Hematopoietic Stem Cell Hibernation. Executive. T. Burn. METU Biology; Stem Cell AU center.
• BAP Hacettepe: Candidate Characterization Quality Control Test Preliminary Study for the Banking Process of Induced Pluripotent Stem Cell uPKH Production. 2018-2020. Executive. D.Uçkan-Çetinkaya; Stem Cell AU center.
• BAP Hacettepe: Title of the Project Investigation of RANTES and Receptors in the Human Bone Marrow Microenvironment. 014D07940001 HÜ-BAP project 01/10/2014 - 01/10/2016 .. Executive. D.Uçkan-Çetinkaya. Stem Cell AU Center.
• Hacettepe University BAP THD-2015-7289 (25.08.2015-09.05.2016). "Effect of In vivo GCSF Application on Bone Marrow Derived Mesenchymal Stem Cell miRNA Expression of Healthy Donors". Executive. A.Günel-Özcan. Stem Cell Sciences; Stem Cell AU center.
• BAP Hacettepe: THD-2018-17187 HÜ-BAP, 15/07 / 18- 2019. In vitro based metabolomics and analyzes in mesenchymal stem cell production. 2018-2019. D.Uçkan-Çetinkaya. Stem Cell AU center.
• BAP Hacettepe: Evaluation of histological healing of cartilage defects formed in rat knees by application of decellularized human placental stem cell PRP combinations in different control groups. 2018-2019. Executive. E. Turhan. Orthopedics; Stem Cell AU center
• BAP Hacettepe: The Relationship Between Angiogenic Factor Levels and GvHD Risk in Patients Undergoing Hematopoietic Stem Cell Transplantation. 2018-2020. Coordinator: F. V. Okur; Pad. Hematology; Stem Cell AU Center
• BAP HAcettepe. Characterization of Leukemia Initiating Cells in Acute Myeloid Leukemia Patient Samples. 2018. Project No: 17051 Coordinator: F. V. Okur. Pad. Hematology; Stem Cell AU Center
• BAP Hacettepe: Evaluation of Pluripotency Properties and In vitro Differentiation Potentials of Human Induced Pluripotent Stem Cells Developed with Episomal Vector, Project No: THD-2017-14504. 2017. Coordinator: F.V.Okur. Stem Cell AU Center.
• Hacettepe University BAP. THD-2016-12080 (13.12.2016-15.11.2019). "Effect of Induced Mesenchymal Stem Cells on Podocyte Chemical Damage Model". Executive. A.Günel-Özcan. Stem Cell Sciences; Stem Cell AU center.
• BAP Hacettepe. THD-2015-8178 (2015-2019) Establishment of an in-vitro mitochondria damage model with human bone marrow mesenchymal stem cells. 2015-2018. Executive. G. Ax. Pad. Hematology. Stem Cell AU Center.
• Hacettepe University Scientific Research Unit Project TKG-2017-15127 (2017-2017) Vascular graft formation: Combination of smooth muscle cells and fibroblasts differentiated from human umbilical cord vein CD146 + cells with human extracellular matrix proteins. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• Hacettepe University Scientific Research Unit Project TBI-2018-16951 (2018-2019) Tissue and organ development with organ on a chip technology. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• Hacettepe University Scientific Research Unit Project TYL-2019-17802 (2019-2019) Evaluation of Human Umbilical Cord Vein CD146 + Cells and Matrix Proteins From These Cells in In Vitro Biofilm Models. Coordinator: B. Çelebi-Saltık. Stem Cell Sciences; Stem Cell AU center.
• 013D02102001 HÜ-BAP project 01/10/2013 - 01/12/2017 Characterization of immune properties of CD271 + MSCs isolated from placenta, cord blood and bone marrow and investigation of immunohematopoiesis-supporting properties. Executive. F.Aerts-Kaya. Stem Cell Sciences; Stem Cell AU center ..
• THD-2018-17209 HÜ-BAP, 15/07/18 - 15/11/19 Investigation of the Role of Neuropeptide Y (NPY) in Hematopoietic Stem Cell Hibernation. Executive. F.Aerts-Kaya. Stem Cell Sciences; Stem Cell AU center.
• TYL-2018-17435 HÜ-BAP, 02/10/18 - 16/12/19 The role of Delta-Opioid Peptide D-Ala2-Leu5-Enkephalin in the survival of Hematopoietic Stem Cells and investigation of its antioxidative and antiapoptotic effects. Executive. F.Aerts-Kaya. Stem Cell Sciences; Stem Cell AU center.
• Bone marrow derived mesenchymal stem cells ameliorate inflammatory response in an in vitro model of familial hemophagocytic lymphohistiocytosis. Sevim H, Kocaefe YÇ, Onur MA, Uçkan-Çetinkaya D, Gürpınar ÖA. Stem Cell Res Ther. 2018 Jul 18; 9 (1): 198. doi: 10.1186 / s13287-018-0941-y.
• G-CSF treatment of healthy pediatric donors affects their hematopoietic microenvironment through changes in bone marrow plasma cytokines and stromal cells. Aerts-Kaya F, Kilic E, Köse S, Aydin G, Cagnan I, Asparagus B, Uckan-Cetinkaya D. Cytokine 2021.
• Bone marrow mesenchymal stem cell donors with a high body mass index display elevated endoplasmic reticulum stress and are functionally impaired. Ulum B, Teker HT, Sarikaya A, Balta G, Kuskonmaz B, Uckan-Cetinkaya D, Aerts-Kaya F.J Cell Physiol. 2018 Nov; 233 (11): 8429-8436. doi: 10.1002 / jcp.26804. Epub 2018 May 24.
• Osteopetrotic induced pluripotent stem cells derived from patients with different disease-associated mutations by nonintegrating reprogramming methods. Okur FV, Cevher I, Özdemir C, Kocaefe C and Uçkan Çetinkaya D. Stem Cell Research & Therapy (2019) 10: 211. doi.org/10.1186/s13287-019-1316-8
• DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic and acute myeloblastic leukemia. Ozdogan H, Gur Dedeoglu B, Oztemur Wetoglu Y, Aydos A, Kose S, Atalay A, Yegin ZA, Avcu F, Uckan Cetinkaya D, Ilhan O. Leuk Res. 2017 Dec; 63: 62-71. doi: 10.1016 / j.leukres.2017.10.006. Epub 2017 Oct 31.
• SUL-109 Protects Hematopoietic Stem Cells from Apoptosis Induced by Short-Term Hypothermic Preservation and Maintains Their Engraftment Potential. Aerts-Kaya FSF, Visser TP, Pervin B, Mammadova A, Özyüncü Ö, Wagemaker G, Uçkan-Çetinkaya FD. Biol Blood Marrow Transplant. 2020 Apr; 26 (4): 634-642. doi: 10.1016 / j.bbmt.2019.12.770. Epub 2020 Jan 7.
• Human bone marrow mesenchymal stem cells secrete endocannabinoids that stimulate in vitro hematopoietic stem cell migration effectively comparable to beta-adrenergic stimulation. KOSE, S., AERTS-KAYA, F. S. F., Kopru, C. Z., NEMUTLU, E., Koskonmaz, B., KARAOSMANOĞLU, B., TASKIRAN, E. Z. (2018). EXPERIMENTAL HEMATOLOGY, vol.57, 30-41.
• Bone marrow mesenchymal stem cells carrying fancd2 mutation differ from the other fanconi anemia complementation groups in terms of TGF-β1 Production.I Cagnan, A Gunel-Ozcan, F Aerts-Kaya et al. Stem Cell Reviews Reports, 2018
• PKNOX2 expression and regulation in the bone marrow mesenchymal stem cells of Fanconi anemia patients and healthy donors. Cagnan I, Cosgun E, Topic O, Uckan D, Gunel-Ozcan A. Mol Biol Rep. 2019 Feb; 46 (1): 669-678. doi: 10.1007 / s11033-018-4522-z
• PKNOX2 regulated by TGFbeta is a new candidate to explain bone marrow failure in fanconi anemia. Cagnan I., Ö Subject, D Uckan-Cetinkaya, A Gunel-Ozcan. Experimental Hematology. 2017
• Neuropeptide Y is involved in the regulation of quiescence of hematopoietic stem cells. Ulum B, Mammadova A, Özyüncü Ö, Uçkan-Çetinkaya D, Yanık T, Aerts-Kaya F. Neuropeptides. 2020 Apr; 80: 102029. doi: 10.1016 / j.npep.2020.102029. Epub 2020 Feb 19.
• Characterization of mesenchymal stem cells in mucolipidosis type II (I-cell disease). Köse S, Aerts Kaya F, Asparagus B, Uçkan Çetinkaya D.Turk J Biol. 2019 Jun 13; 43 (3): 171-178. doi: 10.3906 / bio-1902-20. eCollection 2019.
Automated washing of long-term cryopreserved peripheral blood stem cells promotes cell viability and preserves CD34 + cell numbers.Aerts-Kaya F, Koca G, Sharafi P, Sayla FÇ, Uçkan-Çetinkaya D, Özdemir E. Bon Marrow Transplant. 2018 Sep; 53 (9): 1225-1227. doi: 10.1038 / s41409-018-0192-7. Epub 2018 Apr 27.
Stem cells combined 3D electrospun nanofibrous and macrochannelled matrices: a preliminary approach in repair of rat cranial bones.İşoğlu İA, Bölgen N, Korkusuz P, Vargel İ, Çelik HH, Kılıç E, Güzel E, Çavuşoğlu T, Uçkan D, Piskin E Artif Cells Nanomed Biotechnol. 2019 Dec; 47 (1): 1094-1100. doi:
• Neurological Regulation of the Bone Marrow Niche. Aerts-Kaya F, Ulum B, Mammadova A, Köse S, Aydin G, Korkusuz P, Uçkan-Çetinkaya D.Adv Exp Med Biol. 2020; 1212: 127-153. doi: 10.1007 / 5584_2019_398.
• Dual Effect of Glucocorticoid-Induced Tumor Necrosis Factor-Related Receptor Ligand Carrying Mesenchymal Stromal Cells on Small Cell Lung Cancer: A Preliminary in vitro Study. Kopru CZ, Cagnan I, Akar I, Esendagli G, Korkusuz P, Gunel-Ozcan ACytotherapy. 2018 Jul; 20 (7): 930-940. doi: 10.1016 / j.jcyt.2018.05.002
The Effects of Hypericum perforatum L. on the Proliferation, Osteogenic Differentiation, and Inflammatory Response of Mesenchymal Stem Cells from Different Niches.Mendi A, Gökçınar Yağcı B, Saraç N, Kızıloğlu M, Uğur A, Uçkan D, Yılmaz D. Cells Tissues Organs. 2018; 205 (4): 208-216. doi: 10.1159 / 000491633. Epub 2018 Aug 17.PMID: 30121675
• Stem cell-based small-diameter vascular grafts in dynamic culture. Çelebi-Saltik B, Öseyaka MÖ, Gökçinar-Yagci B. Connect Tissue Res. 2019 Aug 13: 1-13. doi: 10.1080 / 03008207.2019.1651848.
• Generation of human umbilical cord vein CD146 + perivascular cell origined three-dimensional vascular construct. Gökçinar-Yagci B, Yersal N, Korkusuz P, Çelebi-Saltik B. Microvasc Res. 2018 Jul; 118: 101-112. doi: 10.1016 / j.mvr.2018.03.005.ü
• Transcriptome and proteome profiles of human umbilical cord vein CD146 + stem cells. Gökçinar-Yagci B, Karaosmanoglu B, Taskiran EZ, Çelebi-Saltik B. Mol Biol Rep. 2020 May; 47 (5): 3833-3856. doi: 10.1007 / s11033-020-05474-8
• A New Chapter for Mesenchymal Stem Cells: Decellularized Extracellular Matrices. Anase Y, Ozgul RK, Uckan-Cetinkaya D.Stem Cell Rev Rep. 2017 Oct; 13 (5): 587-597. doi: 10.1007 / s12015-017-9757-x.
• The Fibrogenic Activation Kinetics of Stromal Stem Cells in Three Different Skeletal Muscle Degeneration Models. Cansu Özdemir Saka, Duygu Akçay, Diğdem Yöyen Ermiş, Zihni Ekim Taşkiran, Güneş Esendağli, Yusuf Çetin Kocaefe. FEBS Open Bio, 2018
• Endocannabinoids modulate apoptosis in endometriosis and adenomyosis. Bilgic E, Guzel E, Kose S, Aydin MC, Karaismailoglu E, Akar I, Usubutun A, Korkusuz P. Acta Histochem. 2017 Jun; 119 (5): 523-532. doi: 10.1016 / j.acthis.2017.05.005. Epub 2017 May 23.PMID: 28549792.
• Comparison of different culture conditions for smooth muscle cell differentiation of human umbilical cord vein CD146 + perivascular cells. Gökçinar-Yagci B, Çelebi-Saltik B. Cell Tissue Bank. 2017 Dec; 18 (4): 501-511. doi: 10.1007 / s10561-017-9656-z.
• Isolation, characterization and comparative analysis of human umbilical cord vein perivascular cells and cord blood mesenchymal stem cells. Gökçinar-Yagci B, Özyüncü Ö, Çelebi-Saltik B. Cell Tissue Bank. 2016 Jun; 17 (2): 345-52. doi: 10.1007 / s10561-015-9542-5
• Microbial stresses on human umbilical cord stem cells. Kart D, Celebi-Saltik B. Curr Stem Cell Res Ther. 2020 Mar 9.doi: 10.2174 / 1574888X15666200309144334.
• Evaluation of the biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa on human umbilical cord CD146 + stem cells and stem cell-based decellularized matrix. Çankirili NK, Kart D, Çelebi-Saltik B. Cell Tissue Bank. 2020 Jun; 21 (2): 215-231. doi: 10.1007 / s10561-020-09815-6.
Skin Stem Cells, Their Niche and Tissue Engineering Approach for Skin Regeneration. Çankirili NK, Altundag O, Çelebi-Saltik B. Adv Exp Med Biol. 2020; 1212: 107-126. doi: 10.1007 / 5584_2019_380.
• Pericytes: Properties, Functions and Applications in Tissue Engineering. Gökçinar-Yagci B, Uçkan-Çetinkaya D, Çelebi-Saltik B. Stem Cell Rev Rep. 2015 Aug;11(4):549-59. doi: 10.1007/s12015-015-9590-z.
• Pericytes in Tissue Engineering. Çelebi-Saltik B. Adv Exp Med Biol. 2018;1109:125-137. doi: 10.1007/978-3-030-02601-1_10.
• Lactobacillus rhamnosus could inhibit Porphyromonas gingivalis derived CXCL8 attenuation. Mendi A, Köse S, Uçkan D, Akca G, Yilmaz D, Aral L, Gültekin SE, Eroğlu T, Kiliç E, Uçkan S. J Appl Oral Sci. 2016 Jan-Feb;24(1):67-75. doi: 10.1590/1678-775720150145. PMID: 27008259; PMCID: PMC4775012.
• Angiopoietins in the bone marrow microenvironment of acute lymphoblastic leukemia.Karakurt N, Aksu T, Koksal Y, Yarali N, Tunc B, Uckan-Cetinkaya D, Ozguner M.Hematology. 2016 Jul;21(6):325-31. doi: 10.1080/10245332.2015.1125078. Epub 2016 Mar 1.
• Additive effect of mesenchymal stem cells and defibrotide in an arterial rat thrombosis model. Dilli D, Kılıç E, Yumuşak N, Beken S, Uçkan Çetinkaya D, Karabulut R, Zenciroğlu AL.Arch Argent Pediatr. 2017 Jun 1;115(3):249-256. doi: 10.5546/aap.2017.eng.249.
• The Effect of Granulocyte Colony-Stimulating Factor on Immune-Modulatory Cytokines in the Bone Marrow Microenvironment and Mesenchymal Stem Cells of Healthy Donors.Ok Bozkaya I, Azik F, Tavil B, Koksal Y, Ozguner M, Tunc B, Uckan Cetinkaya D.Biol Blood Marrow Transplant. 2015 Nov;21(11):1888-94. doi: 10.1016/j.bbmt.2015.08.007. Epub 2015 Aug 8.
• Mesenchymal stem cell application in children with subacute sclerosing panencephalitis Kuşkonmaz B, Uçkan D, Yalnizoğlu D, Günel M, Karli Oğuz K, Konuşkan B, Anlar B Dev Med Child Neurol. 2015 Sep;57(9):880-3. doi: 10.1111/dmcn.12747. Epub 2015 Apr 6.
• Articular Cartilage Regeneration Utilizing Decellularized Human Placental Scaffold, Mesenchymal Stem Cells and Platelet Rich Plasma.Özdemir E, Emet A, Hashemihesar R, Yürüker ACS, Kılıç E, Uçkan Çetinkaya D, Turhan E.Tissue Eng Regen Med. 2020 Dec;17(6):901-908. doi: 10.1007/s13770-020-00298-w. Epub 2020 Oct 8.
• Stem Cell and Advanced Nano Bioceramic Interactions.Kose, S., Kankilic, B., GİZER, M., Dede, E. C. , Bayramli, E., KORKUSUZ, P., ... KORKUSUZ, F.(2018). NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE , vol.1077, 317-342.
• Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. Erbaba B, Burhan ÖP, Şerifoğlu N, Muratoğlu B, Kahveci F, Adams MM, Arslan-Ergül A Neurobiol Aging. 2020 Oct;94:164-175. doi:10.1016/j.neurobiolaging.2020.04.017. Epub 2020 May 12. PMID: 32629311.
• Expression Levels of SMAD Specific E3 Ubiquitin Protein Ligase 2 (Smurf2) and its Interacting Partners Show Region-specific Alterations During Brain Aging. Sasik MUT, Eravsar ETK, Kinali M, Ergul AA, Adams MM. Neuroscience. 2020 Jun 1;436:46-73. doi: 10.1016/j.neuroscience.2020.04.003. Epub 2020 Apr 8. PMID: 32278060.
• Effects of Syzygium aromaticum, Cinnamomum zeylanicum, and Salvia triloba extracts on proliferation and differentiation of dental pulp stem cells. Mendi A, Yağci BG, Kiziloğlu M, Saraç N, Yilmaz D, Uğur A, Uçkan D. J Appl Oral Sci. 2017 Sep-Oct;25(5):515-522. doi: 10.1590/1678-7757-2016-0522. PMID: 29069149;PMCID: PMC5804388.
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