Elektrokimyasal Arayüzeyler ve Biyomalzemeler Araştırma Grubu'nun temel araştırma alanları; sensörler, yarı iletkenler, elektrokromik cihazlar ve nano ölçekli elektronikler gibi biyomedikal ve enerji uygulamaları için hızla gelişen elektrokimya ve biyomalzeme alanlarına odaklanmaktadır. Şu anda ilgilenilen konular, teşhis, gıda güvenliği ve çevresel izleme alanları için yarı iletkenlerin ve kimyasal/ biyolojik sensörlerin tasarımı ve imalatıdır.
• Potansiyostat/Galvanostat (2 adet)
• Işık mikroskobu
• Plazma cihazı
• Spin coater
• Prof. Dr. Serdar Abacı
• Dr. Öğr. Üy. Gülçin Bolat
• Dr. Öğr. Gör. Öznur Akbal Vural
• Dr. Öğr. Gör. Yeşim Tuğçe Yaman
• Yük. Lis. Öğr. Hatice Büşra Karagöz
• Elektrokimyasal Tekniklerle Yarıiletken İnce Film Üretimi ve Uygulamaları, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Kapsamlı Araştırma Projesi, 2018-2021.
• Hastalıkların Erken Tespiti İçin İn Vitro Diyagnostik Sistemlerin Tasarımı ve Geliştirilmesi, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Doktora Tez Projesi, 2018-2021.
• Elektrokimyasal İmpedimetrik Sensörlerin Geliştirilmesi ve Uygulamaları, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Doktora Tez Projesi, 2018-2021.
• Gıda ve Su Örneklerinde Pestisitlerin Ultra Hassas Algılanması İçin Protein Temelli Yeni Nesil Nanosensörlerin Tasarımı, K. Araştırma, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Kapsamlı Araştırma Projesi, Yürütücü, 2019-devam ediyor.
• Azo Boyar Madde Sentezi ve Karakterizasyonu, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Hızlı Destek Projesi, Yürütücü, 2016-2017.
• Zirai Ürünlerde Pestisitlerin Hızlı Tayini için Elektrokimyasal Nanosensör, Tarımsal Araştırmalar ve Politikalar Genel Müdürlüğü, (TAGEM), AR-GE Projesi, Yürütücü, 2012- 2018.
• Peptit Nanopartikül Temelli Gerilim Duyarlı İlaç Taşıyıcı Sistemlerin Geliştirilmesi, Hızlı Destek, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Hızlı Destek Projesi, Yürütücü, 2017-2018.
• Kil Bazlı Nanokompozit Yapıların Elektrokimyasal Biyosensör Uygulamasının Geliştirilmesi, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Hızlı Destek Projesi, Yürütücü, 2018-2019.
• Dopamin Teşhisi İçin Düşük Maliyetli Yüksek Duyarlık ve Seçicilik Gösteren Sensörlerin Geliştirilmesi, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Hızlı Destek Projesi, Yürütücü, 2018-2019.
• Elektrokimyasal Tekniklerle Yarıiletken İnce Film Üretimi ve Uygulamaları, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Kapsamlı Araştırma Projesi, 2018-2021.
• Hastalıkların Erken Tespiti İçin İn Vitro Diyagnostik Sistemlerin Tasarımı ve Geliştirilmesi, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Doktora Tez Projesi, 2018-2021.
• Elektrokimyasal İmpedimetrik Sensörlerin Geliştirilmesi ve Uygulamaları, Hacettepe Üniversitesi Bilimsel Araştırmalar Birimi, Doktora Tez Projesi, 2018-2021.
. Oznur Akbal Vural., Yesim Tugce Yaman, Serdar Abaci, "Secondary metabolite‐entrapped, anti‐GPA33 targeted poly‐dopamine nanoparticles and their effectiveness in cancer treatment" Journal of Applied Polymer Science, 2022, 139(22), 52274.
. Yesim Tugce Yaman, Oznur Akbal Vural, Gulcin Bolat and Serdar Abaci, “Peptide nanotubes/self-assembled polydopamine molecularly imprinted biochip for the impedimetric detection of human Interleukin-6” Bioelectrochemistry, 2022, 145, 108053. https://doi.org/10.1016/j.bioelechem.2022.108053
. Yesim Tugce Yaman, Gulcin Bolat, Serdar Abaci, Turkan Busra Saygı, “Peptide nanotube functionalized molecularly imprinted polydopamine based single‐use sensor for impedimetric detection of malathion” Analytical and Bioanalytical Chemistry, 2021, 1-14. https://doi.org/10.1007/s00216-021-03737-2
. Gülçin Bolat, “İnsan serum albümin nanopartikül/surfaktant polimer temelli sensör ile metil paratiyonun enzimsiz elektroanalizi” Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2021, 9, 482- 499. doi: 10.29130/dubited.797428
. Gulcin Bolat, Oznur Akbal Vural, Yesim Tugce Yaman, Serdar Abaci, “Label-free impedimetric miRNA-192 genosensor platform using graphene oxide decorated peptide nanotubes composite” Microchemical Journal, 2021, 166, 106218. https://doi.org/10.1016/j.microc.2021.106218
. Oznur Akbal Vural, Yesim Tugce Yaman, Gulcin Bolat and Serdar Abaci, “Human Serum Albumin Gold Nanoparticle Based Impedimetric Sensor for Sensitive Detection of miRNA- 200c” Electroanalysis, 2021, 33, 925-935. https://doi.org/10.1002/elan.202060342
. Yesim Tugce Yaman, Gulcin Bolat, Turkan Busra Saygin, Serdar Abaci “Molecularly imprinted label-free sensor platform for impedimetric detection of 3-monochloropropane-1,2˗diol” Sensors and Actuators B: Chemical, 2021, 328, 128986. (SCI kapsamında dergi- Q1 dilimi) https://doi.org/10.1016/j.snb.2020.128986
. Gulcin Bolat, Oznur Akbal Vural, Yesim Tugce Yaman, Serdar Abaci, “Polydopamine nanoparticles-assisted impedimetric sensor towards label-free lung cancer cell detection” Materials Science and Engineering: C, 2021, 119, 111549. https://doi.org/10.1016/j.msec.2020.111549
. Gulcin Bolat “Investigation of poly (CTAB-MWCNTs) composite based electrochemical DNA biosensor and interaction study with anticancer drug Irinotecan” Microchemical Journal, 2020, 159, 105426. https://doi.org/10.1016/j.microc.2020.105426
• Gulcin Bolat, Yesim Tugce Yaman, Ceren Yardimci, Serdar Abaci, “Gold nanoparticles/graphene oxide based disposable sensor system for voltammetric detection of ceftizoxime” , Hittite Journal of Science & Engineering, 2020, 7, 89-97. https://doi.org/10.17350/HJSE19030000177
• Yesim Tugce Yaman, Oznur Akbal, Gulcin Bolat, Serdar Abaci, “One-pot synthesized gold nanoparticle-peptide nanotube modified disposable sensor for impedimetric recognition of miRNA 410” , Sensors and Atuators B: Chemical, 2020, 320, 128343. https://doi.org/10.1016/j.snb.2020.128343
• Gulcin Bolat, Yesim Tugce Yaman, Filiz Kuralay, Serdar Abaci, “Ultrathin polypyrrole films on self-assembled monolayers as an efficient ultramicroelectrode assay” , Journal of Applied Polymer Science, 2020, 49313. https://doi.org/10.1002/app.49313
• Oznur Akbal, Gulcin Bolat, Yesim Tugce Yaman, Serdar Abaci, “Folic acid conjugated Prussian blue nanoparticles: Synthesis, physicochemical characterization and targeted cancer cell sensing”, Colloids and Surfaces B: Biointerfaces, 2020, 187, 110655. https://doi.org/10.1016/j.colsurfb.2019.110655
• Beyhan Buse Yücebaş, Yesim Tugce Yaman, Gulcin Bolat, Erdoğan Özgür, Lokman Uzun, Serdar Abaci, “Molecular imprinted electrochemical sensor for selective detection of paraben”, Sensors and Actuators B: Chemical, 2020, 305, 127368. https://doi.org/10.1016/j.snb.2019.127368
• Oznur Akbal Vural, “Sericin-montmorillonite composite nanoparticles as drug delivery system in human liver cancer: development, drug release, cellular uptake and cytotoxicity”, Süleyman Demirel University Journal of Natural and Applied Sciences, 2020, 24:1, 169-177. https://doi.org/10.19113/sdufenbed.660323
• Oznur Akbal, Gulcin Bolat, Serdar Abaci, “Clay-protein nanocomposite based electrochemical sensor for the determination of ascorbic acid”, Süleyman Demirel University Journal of Natural and Applied Sciences, 2020, 24:1, 80-89. https://doi.org/10.19113/sdufenbed.562072
• Gulcin Bolat, “Investigation of poly (CTAB-MWCNTs) composite based electrochemical DNA biosensor and interaction study with anticancer drug Irinotecan”, Microchemical Journal, 2020, 159, 105426. https://doi.org/10.1016/j.microc.2020.105426
• Ozge Surucu, Serdar Abaci, “Electrochemical determination of β-lactoglobulin in whey proteins”, Journal of Food Measurement and Characterization, 2020, 14, 11-19. https://doi.org/10.1007/s11694-019-00262-w
• Juliane R. Sempionatto, Laís Canniatti Brazaca, Laura García-Carmona, Gulcin Bolat, Alan S. Campbell, Aida Martin, Guangda Tang, Rushabh Shah, Rupesh K. Mishra, Jayoung Kim, Valtencir Zucolotto, Alberto Escarpa, Joseph Wang, “Eyeglasses-based tear biosensing system: Non-invasive detection of alcohol, vitamins and glucose”, Biosensors and Bioelectronics, 2019, 137, 161-170. https://doi.org/10.1016/j.bios.2019.04.058
• Gulcin Bolat, Yesim Tugce Yaman, Serdar Abaci, “Molecularly imprinted electrochemical impedance sensor for sensitive dibutyl phthalate (DBP) determination”, Sensors and ActuatorsB: Chemical, 2019, 299, 127000. https://doi.org/10.1016/j.snb.2019.127000
• Sultan Gürsoy, Nilgün Dükar, Yesim Tugce Yaman, Serdar Abaci, Filiz Kuralay, “Electroactive polyglycine coatings for nanobiosensing applications: Label-free DNA hybridization, DNA-Antitumor agent interaction and antitumor agent determination”, Analytica Chimica Acta, 2019, 1072, 15-24.
• Jesse R. Qualliotine, Gulcin Bolat, Mara Beltrán-Gastélum, Berta Esteban Fernandez de Ávila, Joseph Wang, Joseph A. Califano, “Acoustic nanomotors for detection of human papillomavirus–associated head and neck cancer”, Otolaryngology–Head and Neck Surgery, 2019, 0194599819866407. https://doi.org/10.1177%2F0194599819866407
• Zehra Yazar Aydin, Soheil Malekghasemi, Serdar Abaci, “Underpotential co-deposition of ternary Cu-Te-Se semiconductor nanofilm on both flexible and rigid substrates”, Applied Surface Science, 2019, 470, 658-667. https://doi.org/10.1016/j.apsusc.2018.11.110
• Yesim Tugce Yaman, Oznur Akbal, Serdar Abaci, “Development of clay-protein based composite nanoparticles modified disposable sensor platform for electrochemical cytosensing application”, Biosensors and Bioelectronics, 2019, 132, 230-237. https://doi.org/10.1016/j.bios.2019.02.058
• Damla Kiziltan, Tayfun Vural, Cem Bayram, Serhat Ozturk, Betul Bozdogan, Yesim Tugce Yaman, Serdar Abaci, Emir Baki Denkbas, “Development of titania nanotube based electrochemical immunosensor for determination of prostate specific antigen”, Analytical Sciences, 2018, 34, 789-794. https://doi.org/10.2116/analsci.17P407
• Yesim Tugce Yaman, Gulcin Bolat, Ceren Yardimci, Serdar Abaci, “An ionic liquid/bismuth film-modified sensor for the electrochemical detection of cefixime”, Turkish Journal of Chemistry, 2018, 42, 826-838. https://doi.org/10.3906/kim-1710-17
• Yesim Tugce Yaman, Öznur Akbal, Gulcin Bolat, Betul Bozdogan, Emir Baki Denkbas, Serdar Abaci, “Peptide nanoparticles (PNPs) modified disposable platform for sensitive electrochemical cytosensing of DLD-1 cancer cells”, Biosensors and Bioelectronics, 2018, 104, 50-57. https://doi.org/10.1016/j.bios.2017.12.039
• Tayfun Vural, Yesim Tugce Yaman, Serhat Ozturk, Serdar Abaci, Emir Baki Denkbas, “Electrochemical immunoassay for detection of prostate specific antigen based on peptide nanotube-gold nanoparticle-polyaniline immobilized pencil graphite electrode”, Journal of Colloid & Interface Science, 2018, 510, 318-326. https://doi.org/10.1016/j.jcis.2017.09.079
• Gulcin Bolat, Yesim Tugce Yaman, Serdar Abaci, “Highly sensitive electrochemical assay for bisphenol A detection based on poly (CTAB)/MWCNTS modified pencil graphite electrodes”, Sensors and Actuators B: Chemical, 2018, 255, 140-148. https://doi.org/10.1016/j.snb.2017.08.001
• Betul Bozdoğan, Oznur Akbal, Ekin Celik, Mustafa Türk, Emir Baki Denkbas, “Novel layer-by-layer self-assembled peptide nanocarriers for siRNA delivery”, Royal Society of Chemistry Advanced, 2018, 7, 47592-47601. https://doi.org/10.1039/C7RA08460A
• Betul Bozdogan, Oznur Akbal, Tayfun Vural, Emir Baki Denkbas, “Synthesis and comparison of cross linked peptide nanoparticles based on diphenylalanine derivatives”, Journal of Applied Polymer Science, 2018, 135(9), 45930. https://doi.org/10.1002/app.45930
• Ebru Erdal, Murat Demirbilek, Yasan Yeh,Oznur Akbal,Laura Ruff, Damla Bozkurt, Ahmet Cabuk, Yasin Senal, Berrak Gumusderelioglu, Oktay Algın, Seyda Colak, Sadık Esener, Emir Baki Denkbas, “A comparative study of reseptor targeted magnetosome and HSA coated iron oxide nanoparticles as MRI contrast enhancing agent in animal cancer model”, Applied Biochemistry and Biotechnology, 2018, 185, 91-113. https://doi.org/10.1007/s12010-017-2642-x
• Oznur Akbal, Tayfun Vural, Soheil Malekghasemi, Betül Bozdoğan, Emir Baki Denkbas, “Saponin loaded montmorillonite-human serum albumin nanocomposites as drug delivery system in colorectal cancer therapy”, Applied Clay Science, 2018, 166, 214-222. https://doi.org/10.1016/j.clay.2018.09.021
• Gulcin Bolat, Serdar Abaci, “Non-enzymatic electrochemical sensing of malathion pesticide in tomato and apple samples based on gold nanoparticles-chitosan-ionic liquid hybrid nanocomposite”, Sensors, 2018, 18(3), 773. https://doi.org/10.3390/s18030773
• Gulcin Bolat, Serdar Abaci, Tayfun Vural, Betul Bozdogan, Emir Baki Denkbas, “Sensitive electrochemical detection of fenitrothion pesticide based on self-assembled peptide-nanotubes modified disposable pencil graphite electrode”, Journal of Electroanalytical Chemistry, 2018, 809, 88-95. https://doi.org/10.1016/j.jelechem.2017.12.060
• Ozge Surucu, Serdar Abaci, “Characterization, and application of azo dye (E)-N-phenyl-4-(thiazole-2-yldiazenyl) aniline (PDA) for biomedical sterilization”, Journal of the Mechanical Behavior of Biomedical Materials, 2018, 77, 408-413. https://doi.org/10.1016/j.jmbbm.2017.09.033
• Ozge Surucu, Gulcin Bolat, Serdar Abaci, “Electrochemical behavior and voltammetric detection of fenitrothion based on a pencil graphite electrode modified with reduced graphene oxide (RGO)/poly (E)-1-(4-((4-(phenylamino) phenyl) diazenyl) phenyl) ethanone (DPA) composite film”, Talanta, 2017, 168, 113–120. https://doi.org/10.1016/j.talanta.2017.03.033
• Zehra Yazar Aydin, Yesim Tugce Yaman, Merve Yasacan, Tamer Cirak, Serdar Abaci, “Anodic stripping voltammetric determination of vardenafil hydrochloride at pencil graphite electrode”, Journal of Iranian Chemical Society, 2017, 14(4), 803-810. https://doi.org/10.1007/s13738-016-1030-8
• Zehra Yazar Aydin, Serdar Abaci, “Characterization of CuTe nanofilms grown by underpotential deposition based on an electrochemical codeposition technique”, Journal of Solid State Electrochemistry, 2017, 21, 1417-1430. https://doi.org/10.1007/s10008-016-3496-9
• Ozge Surucu, Serdar Abaci, “Electrochemical studies on the interaction between (E)-4-((6-Methoxybenzo[d]thiazol-2-yl) diazenyl)-N-Phenylaniline (MBDPA) and bovine serum albumin”, Chemistry Select, 2017, 2, 707. https://doi.org/10.1002/slct.201601657
• Ozge Surucu, Serdar Abaci, “Organic electrochemistry: Basics and applications”, International Journal of Biosensors &Bioelectronics, 2017, 3, 270-271. https://doi.org /10.15406/ijbsbe.2017.03.00063
• Ozge Surucu, Serdar Abaci, “Electrochemical and nonenzymatic glucose biosensor based on MDPA/MWNT/PGE nanocomposite”, Materials Science and Engineering: C, 2017, 78, 539-545. https://doi.org/10.1016/j.msec.2017.04.124
• Zehra Yazar Aydin, Serdar Abaci, “Synthesis and characterization of Cu3Se2 nanofilms by an underpotential deposition based electrochemical codeposition technique”, Solid State Sciences, 2017, 74, 74-87. https://doi.org/10.1016/j.solidstatesciences.2017.10.011
• Oznur Akbal, Ebru Erdal, Tayfun Vural, Doğa Kavaz, Emir Baki Denkbas, “Comparison of protein- and polysaccharide-based nanoparticles for cancer therapy: synthesis, characterization, drug release, and interaction with a breast cancer cell line”, Artificial Cells, Nanomedicine and Biotechnology, 2017, 45(2), 193-203. https://doi.org/10.3109/21691401.2016.1170694
• Yesim Tugce Yaman, Serdar Abaci, “Sensitive adsorptive voltammetric method for determination of bisphenol a by gold nanoparticle/polyvinylpyrrolidone-modified pencil graphite electrode”, Sensors, 2016, 16(6), 756. https://doi.org/10.3390/s16060756
• Ozge Surucu, Gulcin Bolat, Ahmad El-Khouly, Miyase Gozde Gunduz, Rahime Simsek, Serdar Abaci, Filiz Kuralay, Cihat Safak, “Electrochemical detection of antioxidant activities of 1,4-dihydropyridine derivatives”, Hacettepe Journal of Biology and Chemistry, 2016, 44, 535–548. https://doi.org/10.15671/HJBC.2016.134
• Ozge Surucu, Serdar Abaci, Zeynel Seferoğlu, “Electrochemical characterization of azo dye(E)-1-(4-((4-(phenylamino)phenyl)diazenyl)phenyl)ethenone(DPA)”, Electrochimica Acta, 2016, 195, 175. https://doi.org/10.1016/j.electacta.2016.02.142
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